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ClinicalTrials.gov public records Last synced Oct 8, 2026, 1:56 AM EDT

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Showing 313–336 of 1,255 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Posttraumatic Stress Disorder PTSD Clear all
Completed Early Phase 1 Interventional

A Pilot Study of SPG Block for PTSD

NCT05743543
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Sphenopalatine ganglion block
Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 8, 2026, 1:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Implementation of CPT for PTSD in Diverse Communities

NCT01702168
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Provider training: Cognitive Processing Therapy (CPT)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chelsea, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 8, 2019 · Synced Oct 8, 2026, 1:56 AM EDT
Not yet recruiting Early Phase 1 Interventional

Predictors & Mechanisms of Adolescent PTSD

NCT07537764
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Trauma Exposure
Interventions
Repeated imaginal exposure: Script Driven Imagery (SDI) task
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
14 Years to 18 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional Results available

Improving Function Through Primary Care Treatment of Posttraumatic Stress Disorder (PTSD)

NCT03581981
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Prolonged Exposure for Primary Care (PE-PC), Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Decatur, Georgia • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brazilian Jiu Jitsu vs. Yoga for Treating Symptoms of PTSD

NCT06497400
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Brazilian Jiu Jitsu, Hatha Yoga, Waitlist
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 44 Years · Male only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Evaluation of the Pregnant Moms' Empowerment Program

NCT05011825
View directory record Official record
Conditions
Violence, Depression, Posttraumatic Stress Disorder, Parenting, Infant Development, Child Behavior
Interventions
Pregnant Moms' Empowerment Program
Behavioral
Lead sponsor
University of Notre Dame
Other
Eligibility
16 Years to 55 Years · Female only
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Notre Dame, Indiana • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Oct 8, 2026, 1:56 AM EDT
Not listed Not applicable Interventional

Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD

NCT01663337
View directory record Official record
Conditions
PTSD, Alcohol Abuse, Alcohol Dependence
Interventions
Cognitive Processing Therapy (CPT), Relapse Prevention (RP)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Phase 3 Interventional Results available

Enhancing Exposure Therapy for Post Traumatic Stress Disorder (PTSD): Virtual Reality and Imaginal Exposure With a Cognitive Enhancer

NCT01352637
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
DCS (D-Cycloserine ) + Prolonged Imaginal Exposure, DCS (D-Cycloserine ) + Virtual Reality Exposure, Placebo + Prolonged Imaginal Exposure, Placebo (sugar pill) + Virtual Reality Exposure
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
5
States / cities
Long Beach, California • Los Angeles, California • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Safety & Efficacy Study Using Topiramate in Posttraumatic Stress Disorder

NCT00204386
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Topiramate
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 30, 2007 · Synced Oct 8, 2026, 1:56 AM EDT
Not yet recruiting Not applicable Interventional

Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) for Treatment of Post-Traumatic Stress Disorder (PTSD)

NCT07526285
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 8, 2026, 1:56 AM EDT
Not listed No phase listed Observational

Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort

NCT05855876
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
subanesthetic ketamine infusions and bilateral cervical sympathetic blocks
Procedure
Lead sponsor
Stella Center
Other
Eligibility
40 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Westmont, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 17, 2023 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Phase 3 Interventional Results available

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

NCT03537014
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Therapy, midomafetamine HCl, Placebo
Behavioral · Drug
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
11
States / cities
North Hollywood, California • San Francisco, California • Boulder, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 8, 2026, 1:56 AM EDT
Recruiting Not applicable Interventional

The ED-AWARENESS-2 Trial

NCT05534243
View directory record Official record
Conditions
Awareness, Mechanical Ventilation, Intubation Complication, PTSD
Interventions
Standard neuromuscular blocker practices, Education
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
3,090 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Iowa City, Iowa • Minneapolis, Minnesota • Camden, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional Results available

Trauma-Focused Equine-Assisted Therapy (TF-EAT) for Veterans With PTSD

NCT03068325
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
EAT-PTSD
Other
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional Results available

Telemedicine Management of Chronic Insomnia

NCT01686438
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Post-Traumatic Stress Disorders
Interventions
Cognitive behavioral therapy for insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional

Pain Management Using Mobile Technology in Veterans With PTSD and TBI

NCT02237885
View directory record Official record
Conditions
Chronic Pain, Posttraumatic Stress Disorders, Traumatic Brain Injury
Interventions
NeuroSky MindWave Mobile
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional

Safety and Efficacy of Cognitive Behavior Therapy for People With Post-traumatic Stress and Cardiovascular Illness

NCT00364910
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive behavioral therapy (CBT), Educational session and treatment as usual
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
New York, New York • Queens, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2017 · Synced Oct 8, 2026, 1:56 AM EDT
Recruiting Not applicable Interventional

Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation

NCT06544408
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
Cool B70 AP Coil - Active (dl-PFC), Cool B70 AP Coil- Sham (dl-PFC), Cool D-B80 AP Coil - Active (dm-PFC), Cool D-B80 AP Coil - Sham (dm-PFC), Cool B70 Treatment Coil - Active Only
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 8, 2026, 1:56 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)

NCT07396935
View directory record Official record
Conditions
Trauma, Posttraumatic Stress Disorder
Interventions
Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
7 Years to 14 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 8, 2026, 1:56 AM EDT
Recruiting Not applicable Interventional

TMS for PTSD in Youth

NCT07401225
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
MagPro R30 with robotic arm
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
12 Years to 20 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 8, 2026, 1:56 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery

NCT06222268
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder, Suicide, Cannabis Use
Interventions
Cannabidiol (CBD) only, Placebo only, Delta-9-tetrahydrocannabinol (THC) only, THC:CBD 1:1
Drug
Lead sponsor
Leslie Lundahl
Other
Eligibility
18 Years to 60 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Technology-Based Tools to Enhance Quality of Care in Mental Health Treatment

NCT01915160
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
eTF-CBT, TF-CBT
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
8 Years to 15 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Not applicable Interventional Results available

Tobacco Cessation for Veterans With Post Traumatic Stress Disorder (PTSD)

NCT00908882
View directory record Official record
Conditions
Tobacco Use Cessation, Post Traumatic Stress Disorders
Interventions
Motivation Interviewing Counseling
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 16, 2015 · Synced Oct 8, 2026, 1:56 AM EDT
Completed Phase 4 Interventional Results available

Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments

NCT01490697
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Mifepristone, d-Cycloserine, Placebo-matching Mifepristone, Placebo-matching d-Cycloserine (DCS)
Drug
Lead sponsor
Roger K. Pitman, MD
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 29, 2017 · Synced Oct 8, 2026, 1:56 AM EDT