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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Posttraumatic Stress Disorder PTSD Clear all
Completed Not applicable Interventional Results available

Recovery After Stress Toolkit (RESET) Study

NCT04838977
View directory record Official record
Conditions
Post-Traumatic Stress Disorder in Children, Post-Traumatic Stress Disorder in Adolescence
Interventions
RESET
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
8 Years to 17 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Cincinnati, Ohio • Houston, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Phase 1 Interventional

Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression

NCT00961454
View directory record Official record
Conditions
Major Depression, Anxiety Disorder, Post-Traumatic Stress Disorder, Substance Abuse Disorder
Interventions
Photobiomodulation with a super-luminous light emitting diode
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2009 · Synced Jun 26, 2026, 2:24 AM EDT
Completed No phase listed Observational

Patient Participation Beliefs and Post-Traumatic Stress Disorder (PTSD)

NCT01419223
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Brain Injuries, Traumatic
Interventions
Not listed
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2013 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional

Efficacy of 60-minute Versus 90-minute Sessions in Treating PTSD Using Prolonged Exposure

NCT01911585
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Phase 1 Interventional

Patient-Centered Collaborative Care for Preventing Post-Traumatic Stress Disorder After Traumatic Injury

NCT00270959
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy, Motivational Interviewing, FDA-Approved Anti-Anxiety Medications, Standard Care Control
Behavioral · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Phase 4 Interventional Results available

Atomoxetine in Veterans With Comorbid ADHD/PTSD

NCT02287038
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Atomoxetine 80 MG
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Ketamine and Prolonged Exposure in PTSD

NCT03960658
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
ketamine-enhanced prolonged exposure
Drug
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 21, 2021 · Synced Jun 26, 2026, 2:24 AM EDT
Recruiting Phase 3 Interventional

Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)

NCT06333990
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Quetiapine Fumarate, TAU
Drug
Lead sponsor
Foundation for Advancing Veterans' Health Research
Other
Eligibility
18 Years to 65 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Albuquerque, New Mexico • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional

Multisite Feasibility of Compassion Meditation for Veterans With Posttraumatic Stress Disorder (PTSD)

NCT04793698
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Compassion meditation, Applied relaxation
Other · Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Bedford, Massachusetts • Canandaigua, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Nicotine Patch Pretreatment for Smoking Cessation in PTSD

NCT00625131
View directory record Official record
Conditions
Stress Disorders, Posttraumatic, Tobacco Use Disorder
Interventions
Nicotine, Cognitive Behavioral Therapy for Smoking Cessation, Bupropion Sustained Release (SR), Placebo patch
Drug · Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2014 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional

Study to Promote Innovation in Rural Integrated Telepsychiatry

NCT02738944
View directory record Official record
Conditions
Bipolar Disorder, Posttraumatic Stress Disorder
Interventions
Telepsychiatry Collaborative Care, Telepsychiatry Enhanced Referral
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
13
States / cities
Marianna, Arkansas • Marshall, Arkansas • West Memphis, Arkansas + 10 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2020 · Synced Jun 26, 2026, 2:24 AM EDT
Recruiting Not applicable Interventional

Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

NCT05843695
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anxiety Disorders
Interventions
iTCBT-I, iTCBT-G, TAU
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Jun 26, 2026, 2:24 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Project BrEAtHe: A Culturally Tailored MBSR Intervention for Young Adult Black Men

NCT07009977
View directory record Official record
Conditions
Alcohol Abuse, Substance Abuse, Post Traumatic Stress Disorder
Interventions
self-guided mHealth app only, self-guided mHealth app + 'real-time' feedback
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Tai Chi Resilience Training Program on Objective and Subjective Measures of Post Traumatic Stress Disorder Severity

NCT04288830
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Tai Chi, Aerobic Exercise
Interventions
Tai Chi Moving Mindfulness Meditation and Resilience Training, Aerobic Exercise
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional

Pilot Study of PRX-03140 to Assess Safety for Use in Adult Subjects With Post Traumatic Stress Disorder

NCT01492699
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
PRX-03140
Drug
Lead sponsor
Alachua Government Services, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 24, 2014 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PTSD Training for PCPs in a Virtual World

NCT03898271
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Virtual World
Other
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Jun 26, 2026, 2:24 AM EDT
Recruiting Phase 2 Interventional

MDMA-Assisted Massed Exposure Therapy for PTSD

NCT07288151
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
3,4-Methylenedioxymethamphetamine (MDMA), Placebo, Massed Prolonged Exposure (PE)
Drug · Behavioral
Lead sponsor
Emory University
Other
Eligibility
21 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jun 26, 2026, 2:24 AM EDT
Recruiting Phase 1 Interventional

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

NCT07506395
View directory record Official record
Conditions
PTSD
Interventions
Psilocybin
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 26, 2026, 2:24 AM EDT
Not listed No phase listed Observational

Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort

NCT05855876
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
subanesthetic ketamine infusions and bilateral cervical sympathetic blocks
Procedure
Lead sponsor
Stella Center
Other
Eligibility
40 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Westmont, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 16, 2023 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional

Integrated Intervention Post-Sexual Assault

NCT04724746
View directory record Official record
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder, Sexual Assault
Interventions
Written Exposure and Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD

NCT02641496
View directory record Official record
Conditions
Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
Interventions
CBT-OSA, Sleep Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Oxytocin and Affect Processing in Posttraumatic Stress Disorder

NCT02546570
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Phase 4 Interventional Results available

Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy

NCT01087736
View directory record Official record
Conditions
PTSD, Alcohol Abuse, Alcoholism
Interventions
Topiramate, Placebo administration
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Jun 26, 2026, 2:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)

NCT01466127
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Jun 26, 2026, 2:24 AM EDT