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ClinicalTrials.gov public records Last synced Sep 15, 2026, 4:52 PM EDT

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Showing 1–24 of 73 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Povidone Iodine Clear all
Terminated Not applicable Interventional

Chlorhexidine and/or Betadine Prep in Pediatric Arm Surgery Following Trauma

NCT04225065
View directory record Official record
Conditions
Arm Fracture, Surgical Site Infection
Interventions
Chlorhexidine, Betadine
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
Up to 10 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Phase 1Phase 2 Interventional Results available

PVP-I Nasal Sprays and SARS-CoV-2 Nasopharyngeal Titers (for COVID-19)

NCT04347954
View directory record Official record
Conditions
COVID-19
Interventions
Povidone-Iodine 2%, Povidone-Iodine 0.5%, Isotonic saline 0.9%
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2021 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

SHIELD Study: Using Naso-oropharyngeal Antiseptic Decolonization to Reduce COVID-19 Viral Shedding

NCT04478019
View directory record Official record
Conditions
COVID-19, SARS-CoV 2
Interventions
10% Povidone-iodine nasal decolonization swab plus 0.12% CHG oral rinse
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 13, 2022 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dental Office Prevention Strategies for Children

NCT02004990
View directory record Official record
Conditions
Dental Plaque
Interventions
Single cleansing procedure of 10% Povidone Iodine
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
6 Years to 13 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Sep 15, 2026, 4:52 PM EDT
Active, not recruiting Phase 4 Interventional

PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)

NCT05763602
View directory record Official record
Conditions
Surgical Site Infection
Interventions
povidone-iodine topical ointment
Drug
Lead sponsor
Loreen Herwaldt
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
6
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Iowa City, Iowa + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 15, 2026, 4:52 PM EDT
Not yet recruiting Phase 4 Interventional

Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized Study

NCT04200729
View directory record Official record
Conditions
Acute, Perforated Appendicitis
Interventions
Irrigation with PVI, Usual care
Drug · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
2 Years to 17 Years
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 15, 2026, 4:52 PM EDT
Recruiting Phase 4 Interventional

Nasal Antisepsis for C. Auris Prevention

NCT06282510
View directory record Official record
Conditions
Candida Auris Infection, Colonization, Asymptomatic
Interventions
Povidone Iodine Topical
Drug
Lead sponsor
Mary K Hayden
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Chicago, Illinois • Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Phase 1 Interventional Results available

Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty

NCT04075526
View directory record Official record
Conditions
Osteoarthritis
Interventions
Povidone iodine, Vancomycin powder, Conventional
Drug · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
2,129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
14
States / cities
Rancho Mirage, California • Denver, Colorado • Weston, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.

NCT03349515
View directory record Official record
Conditions
Strabismus
Interventions
Provodine-Iodine Solution, Group B will receive three drops in each eye of ophthalmic balanced salt solution.
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
1 Year to 17 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 15, 2019 · Synced Sep 15, 2026, 4:52 PM EDT
Recruiting Phase 3 Interventional

Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections

NCT06363877
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Povidone-Iodine, Normal Saline
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chlorhexidine Gluconate Versus Povidone Iodine at Cesarean Delivery: a Randomized Controlled Trial

NCT01975805
View directory record Official record
Conditions
Pregnancy, Cesarean Section
Interventions
Chlorhexidine Gluconate, Povidone Iodine
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2013 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients

NCT04364802
View directory record Official record
Conditions
COVID-19, SARS-CoV 2
Interventions
Povidone-Iodine Nasal Spray and Gargle
Drug
Lead sponsor
Nikita Gupta
Other
Eligibility
18 Years to 99 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis

NCT02202577
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Chlorhexidine - Isopropyl alcohol, Povidone-Iodine Scrub and Paint
Drug
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
932 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-Iodine

NCT05934253
View directory record Official record
Conditions
Antiseptic, Anesthesia, Local
Interventions
Chloroprocaine ophthalmic gel 3%
Drug
Lead sponsor
Harrow Inc
Industry
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Brandon, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 15, 2026, 4:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Infection Rates Between Two Surgical Sites

NCT01263262
View directory record Official record
Conditions
Corneal Toxicity, Ototoxicity, Surgical Site Infection
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2013 · Synced Sep 15, 2026, 4:52 PM EDT
Not yet recruiting Phase 3 Interventional Accepts healthy volunteers

Povidone Iodine for Caries Prevention

NCT07741409
View directory record Official record
Conditions
Dental Caries
Interventions
Povidone Iodine 5% Soln,Top,Kit, Probiotics, Placebo
Drug · Dietary Supplement
Lead sponsor
Jeffrey A. Banas
Other
Eligibility
1 Year to 3 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 15, 2026, 4:52 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Betadine vs Sterile Water for Periurethral Preparation

NCT07044726
View directory record Official record
Conditions
Catherization, Urinary Tract Infection Bacterial
Interventions
Povidone-Iodine, Sterile water
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Not applicable Interventional Results available

Bacterial Resistance in Patients Receiving Post-Intravitreal Injection Antibiotics

NCT02223338
View directory record Official record
Conditions
Bacterial Resistance
Interventions
Ciprofloxacin, Standard Aseptic Technique
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Phase 2 Interventional Results available

Povidone-Iodine Oral Rinse Study

NCT05239598
View directory record Official record
Conditions
COVID-19
Interventions
Mouth rinse
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 15, 2026, 4:52 PM EDT
Terminated Phase 4 Interventional

ChloraPrep Versus Betadine for Elective Knee Replacement Surgery

NCT01184196
View directory record Official record
Conditions
Arthroplasty, Knee Replacement, Replacement, Total Knee, Total Knee Replacement
Interventions
Swab area with Betadine, Swab area with ChloraPrep
Drug
Lead sponsor
Central DuPage Hospital
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winfield, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2013 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Phase 4 Interventional

Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study)

NCT04018482
View directory record Official record
Conditions
Age-related Macular Degeneration, Diabetic Retinopathy, Diabetic Macular Edema
Interventions
Povidone Iodine, Hypochlorous Acid
Other
Lead sponsor
California Retina Consultants
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Sep 15, 2026, 4:52 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN)

NCT05127525
View directory record Official record
Conditions
Diabetic Macular Edema, Branch Retinal Vein Occlusion, Glaucoma/Closed Angle Glaucoma
Interventions
IRX-101, Control
Drug
Lead sponsor
iRenix Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 23, 2022 · Synced Sep 15, 2026, 4:52 PM EDT
Completed Not applicable Interventional Results available

Dilute Betadine Soak and Scrub for Foot and Ankle Surgery

NCT03926208
View directory record Official record
Conditions
Postoperative Infection, Postoperative Complications
Interventions
Soak and Scrub, Clorhexadine scrub
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Sep 15, 2026, 4:52 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Topical 10% Povidone-Iodine in Preventing White Spots

NCT06616207
View directory record Official record
Conditions
White Spot Lesions, Gingival Inflammation and Bleeding
Interventions
Placebo, Povidone-iodine solution
Drug
Lead sponsor
University of Washington
Other
Eligibility
10 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 15, 2026, 4:52 PM EDT