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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: PrEP Uptake Clear all
Recruiting Not applicable Interventional

Pre-exposure Prophylaxis (PrEP) for Health

NCT04430257
View directory record Official record
Conditions
Substance Dependence, HIV (Human Immunodeficiency Virus)
Interventions
HIV and PrEP education, Motivational interviewing, Problem-solving and planning, Patient navigation, PrEP information, Referrals
Other · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Cambridge, Massachusetts • Lawrence, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 25, 2026, 11:56 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

An Effectiveness Trial of the PrEP for WINGS Study

NCT06853314
View directory record Official record
Conditions
HIV Infections, Alcohol Use Disorder, Violence, Gender-Based
Interventions
PrEP for WINGS, PrEP Decision Aid
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
307 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pharmacy-based Pre-exposure Prophylaxis

NCT04393935
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Pharmacy Delivered PrEP Intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Peer-Driven Intervention to Increase PrEP Uptake Among Minority MSM

NCT05161663
View directory record Official record
Conditions
HIV Infections
Interventions
Peer-driven intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 25, 2026, 11:56 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PrEP Awareness, Barriers and Facilitators for PrEP Uptake, and Dosing Mechanisms on Willingness to Take PrEP Among MSM

NCT04719364
View directory record Official record
Conditions
PrEP, Discrimination, Racial, Stigma, Social
Interventions
Not listed
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older · Male only
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Short-Term PrEP Uptake for MSM With Episodic High-Risk for HIV

NCT02495779
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
emtricitabine/tenofovir, CBT-based counseling
Drug · Behavioral
Lead sponsor
James Egan
Other
Eligibility
18 Years and older · Male only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Sep 25, 2026, 11:56 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

ED2PrEP - Patient Focused, Low-burden Strategies for PrEP Uptake Among Emergency Departments

NCT05588193
View directory record Official record
Conditions
HIV
Interventions
PVO, TSH
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
1,560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Electronic Health Record Data in a Risk Prediction Model to Increase HIV PrEP Intake in Primary Care

NCT05991869
View directory record Official record
Conditions
Pre-Exposure Prophylaxis
Interventions
Point-of-care decision support intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 25, 2026, 11:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exploring the Perspectives and Experiences of PrEP-eligible Black Women in Texas in Relation to Readiness for PrEP Uptake and Adherence

NCT05530993
View directory record Official record
Conditions
PrEP Uptake Perspectives, PrEP Uptake Experiences, PrEP Adherence Perspectives, PrEP Adherence Experiences
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Austin, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional

OPTIONS: A Patient-Centered HIV Prevention Decision Aid for PrEP Uptake for Women With Substance Use in Treatment Settings

NCT03651453
View directory record Official record
Conditions
HIV Infections, Substance Abuse
Interventions
Decision aid, Standard care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Demonstration Project

NCT04077151
View directory record Official record
Conditions
HIV/AIDS, Gender, Behavior and Behavior Mechanisms
Interventions
PrEP Demonstration Project
Behavioral
Lead sponsor
Hektoen Institute for Medical Research
Other
Eligibility
15 Years to 24 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study

NCT03652623
View directory record Official record
Conditions
HIV/AIDS, Gender, Behavior and Behavior Mechanisms
Interventions
TDF/FTC
Drug
Lead sponsor
Hektoen Institute for Medical Research
Other
Eligibility
15 Years to 24 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 31, 2024 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile-Based Application "MyChoices"

NCT03179319
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
Interventions
MyChoices
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Mobile Intervention to Improve Uptake of PrEP for Southern Black MSM

NCT03308097
View directory record Official record
Conditions
Hiv
Interventions
PrEP Mobile Messaging Intervention, Enhanced Standard of Care
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Sep 25, 2026, 11:56 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing PrEP Uptake for African American Women in the South by Empowering Women to Make Informed HIV Prevention and Sexual Health Choices

NCT07173816
View directory record Official record
Conditions
HIV Pre-exposure Prophylaxis
Interventions
EMPOWER
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional

Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM).

NCT03137342
View directory record Official record
Conditions
PrEP Uptake, Stimulant Abuse, Adherence, Medication
Interventions
Pepped on PrEP Package
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile-health (mHealth) Intervention to Support HIV Self-testing and PrEP Uptake Among Young Men Who Have Sex With Men

NCT04865341
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
IMB, Information-Only Control
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
17 Years to 24 Years · Male only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer Intervention Latino Immigrant MSM

NCT03922126
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
Peer counseling, HIV/STI self-testing kits
Other · Diagnostic Test
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Sep 25, 2026, 11:56 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

HIV Pre-Exposure Prophylaxis Among an Unrecognized Sexual Minority Population

NCT05815030
View directory record Official record
Conditions
Pre-Exposure Prophylaxis
Interventions
video informational/educational intervention
Other
Lead sponsor
The Alternative Sexualities Health Research Alliance
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rio Vista, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 25, 2026, 11:56 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using PrEP, Doing It for Ourselves

NCT06638892
View directory record Official record
Conditions
HIV Prevention, PrEP
Interventions
Using PrEP, Doing it for Ourselves (UPDOs), Standard of Care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

HealthMindr App to Increase Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex With Men (MSM)

NCT03763942
View directory record Official record
Conditions
HIV Infections
Interventions
HealthMindr App, Control App
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
658 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Social Media Based Peer-Led Intervention for HIV Prevention

NCT03213366
View directory record Official record
Conditions
HIV Prevention, PrEP Uptake
Interventions
E-PrEP- Peer-Led Intervention about PrEP, BxNow - General Health Campaign
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 29 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer Outreach and Navigation Intervention to Increase PrEP Uptake Among Women at High Risk for HIV

NCT03226873
View directory record Official record
Conditions
Pre-exposure Prophylaxis, HIV-1-infection
Interventions
Peer Navigation
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2018 · Synced Sep 25, 2026, 11:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervention to Enhance PrEP Uptake and Adherence in a Community-Based Setting

NCT02037594
View directory record Official record
Conditions
Human Immunodeficiency Virus (HIV)
Interventions
Sexual Health Counseling, Enhanced Adherence Intervention, PrEP Information (Active Control), Standard of Care Adherence Support (Active Control)
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years and older · Male only
Enrollment
438 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Sep 25, 2026, 11:56 AM EDT