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Showing 265–288 of 366 matching trials from the live ClinicalTrials.gov search.
Conditions
Pulmonary Hypertension
Interventions
Macitentan, Placebo
Drug
Lead sponsor
Actelion
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
6
States / cities
Louisville, Kentucky • Boston, Massachusetts • Ann Arbor, Michigan + 3 more
Conditions
Pre-hypertension
Interventions
carvedilol phosphate, lisinopril, carvedilol phosphate and lisinopril, placebo and placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
19 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Pre-Eclampsia
Interventions
recombinant human relaxin
Drug
Lead sponsor
Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
2
States / cities
Lexington, Kentucky • Cincinnati, Ohio
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Magnesium Sulfate in Obese Preeclamptics

NCT02835339
Conditions
Preeclampsia
Interventions
Magnesium sulfate 4g loading dose, 1g/hr infusion, Magnesium sulfate 6g loading dose, 2g/hr infusion
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Completed No phase listed Observational Accepts healthy volunteers

Novel Biomarkers of Preeclampsia, Aquaporin, Fatty Acid, and S110B

NCT03567551
Conditions
Preeclampsia
Interventions
Women w/ Preeclampsia w/o Visual Disturbances or Headache, Women w/ Preeclampsia w/ Visual Disturbances or Headaches, Women w/o Preeclampsia
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
20 Years to 65 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Completed No phase listed Observational Accepts healthy volunteers Results available

Platelet Count Trends in Pre-eclamptic Parturients

NCT00787241
Conditions
Obstetric Labor Complications, Preeclampsia, Thrombocytopenia
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
445 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2003
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Predictors of Aspirin Failure in Preeclampsia Prevention

NCT05709483
Conditions
Preeclampsia
Interventions
Aspirin
Drug
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Terminated Not applicable Interventional Results available

PROtecting Maternal Brains From Injury and Stroke

NCT05726279
Conditions
Preeclampsia, Maternal Hypertension
Interventions
NIRS based personalized blood pressure management
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Vitamin D Supplementation

NCT02513823
Conditions
Elevated Blood Pressure, Endothelial Dysfunction
Interventions
2,000 International Units (IU)of vitamin D3
Dietary Supplement
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Conditions
Hypertension
Interventions
iHealth Wireless Blood Pressure Monitor
Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Memphis, Tennessee
Terminated No phase listed Observational Accepts healthy volunteers

Endothelial Progenitor Cells in Umbilical Cord Blood in Preeclampsia and IUGR

NCT00634855
Conditions
Preeclampsia, IUGR
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Preeclampsia
Interventions
2% buffered hypertonic saline administration
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
2
States / cities
Baltimore, Maryland
Conditions
Preeclampsia Postpartum
Interventions
Aspirin 81Mg Ec Tab
Drug
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Long Beach, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Utilization of Somatic Tissue Oxygen Saturation Monitoring in Pregnant Women

NCT03196141
Conditions
Pre-Eclampsia
Interventions
StO2 and EndoPAT
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting No phase listed Observational Accepts healthy volunteers

The Preeclampsia Registry

NCT06377878
Conditions
Preeclampsia, Eclampsia, HELLP Syndrome, Toxemia, Hypertensive Disorder of Pregnancy
Interventions
Not listed
Lead sponsor
Preeclampsia Foundation
Other
Eligibility
13 Years and older
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2040
U.S. locations
1
States / cities
Melbourne, Florida
Terminated Phase 4 Interventional Results available

Postpartum Hypertension Study

NCT05139238
Conditions
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Pregnancy-Induced Hypertension in Postpartum, Hypertensive Emergency
Interventions
Labetalol, Nifedipine
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia

NCT02147626
Conditions
Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
Interventions
Web-based educational and motivational modules, Information and Screening Group
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Preeclampsia
Interventions
Not listed
Lead sponsor
Catalin S Buhimschi, MD
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
346 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Hypertension, Pre Diabetes
Interventions
MegaNatural-BP SR 150Mg Tablet, Placebo Capsule
Dietary Supplement · Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
40 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Terminated No phase listed Observational Accepts healthy volunteers

CONNEQT Pulse Validation Study

NCT06002971
Conditions
Pregnancy Related, Pre-Eclampsia, Gestational Hypertension
Interventions
Blood pressure measurement
Device
Lead sponsor
Mount Carmel Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Preeclampsia Postpartum
Interventions
Remote Patient Monitoring
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Cardiovascular Disease
Interventions
ALT-711 (alagebrium chloride)
Drug
Lead sponsor
Synvista Therapeutics, Inc
Industry
Eligibility
50 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Accepts healthy volunteers Results available

Thoracic Ultrasonography for Pulmonary Edema in Patients With Pre-Eclampsia

NCT02357264
Conditions
Pre-eclampsia
Interventions
Ultrasound
Device
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Brooklyn, New York
Completed Not applicable Interventional Accepts healthy volunteers

Exercise in Pregnancy for Reduction of Blood Pressure in Obese Patients

NCT01261884
Conditions
Hypertension, Pregnancy, Preeclampsia, Exercise
Interventions
Exercise support, Exercise intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Hershey, Pennsylvania