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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:30 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 806 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pre Term Labor Clear all
Active, not recruiting No phase listed Observational

Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes

NCT03782610
View directory record Official record
Conditions
Patent Ductus Arteriosus, Preterm Infant, Bronchopulmonary Dysplasia, Neurodevelopmental Abnormality
Interventions
Not listed
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Up to 72 Hours
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
4
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 22, 2026, 4:30 AM EDT
Not listed Not applicable Interventional

Bilateral Infant Stimulation Study

NCT06353243
View directory record Official record
Conditions
Parent-Child Relations, Preterm Birth, Stress Reaction, Hospitalism in Children
Interventions
Bilateral alternating stimulation
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Not applicable Interventional Results available

Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation

NCT01220687
View directory record Official record
Conditions
Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
Interventions
iNO, Nitrogen
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Minute to 2 Minutes
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Not applicable Interventional Results available

Relationship Between EIT and Respiratory Status in Very Preterm Infants

NCT06609135
View directory record Official record
Conditions
Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia, Premature Lungs
Interventions
Sentec LuMon Device (EIT system), Sentec Digital Monitoring System (transcutaneous CO2 monitor)
Device
Lead sponsor
Lawrence Rhein
Other
Eligibility
5 Days and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 22, 2026, 4:30 AM EDT
Completed No phase listed Observational

Improving Prematurity-Related Respiratory Outcomes at Vanderbilt

NCT01460576
View directory record Official record
Conditions
Preterm Birth, Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 7 Days
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Jackson, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2017 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Phase 3 Interventional

Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight

NCT00114543
View directory record Official record
Conditions
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Aggressive Phototherapy 501-750g, Aggressive Phototherapy 751-1000g, Conservative Phototherapy 501-750g, Conservative Phototherapy 751-1000g
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
12 Hours to 36 Hours
Enrollment
1,974 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 22, 2026, 4:30 AM EDT
Recruiting Phase 2 Interventional

Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project

NCT06004674
View directory record Official record
Conditions
Adverse Pregnancy Outcome
Interventions
Lovenox 40mg
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

This Study Will Investigate the Effect of Single Oral Doses of Retosiban on Cardiac Repolarization, With Moxifloxacin as a Positive Control in Healthy Volunteers.

NCT01702376
View directory record Official record
Conditions
Obstetric Labour, Premature
Interventions
Retosiban 100 mg, Retosiban 800 mg, Placebo, Moxifloxacin 400 mg
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 45 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 12, 2017 · Synced Oct 22, 2026, 4:30 AM EDT
Withdrawn Not applicable Interventional

Dino Egg in Neonatal Intensive Care Unit

NCT03447405
View directory record Official record
Conditions
Premature Birth
Interventions
Dino Egg
Device
Lead sponsor
Jonathan Slaughter
Other
Eligibility
32 Weeks to 34 Weeks
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 22, 2026, 4:30 AM EDT
Not listed Not applicable Interventional

A Study to Evaluate the Efficacy of Seattle-PAP for the Respiratory Support of Premature Infants

NCT03085329
View directory record Official record
Conditions
Premature Birth
Interventions
Seattle-PAP, Conventional bubble nasal CPAP
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Up to 30 Weeks
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 22, 2017 · Synced Oct 22, 2026, 4:30 AM EDT
Recruiting No phase listed Observational

Preterm Lung Patient Registry

NCT00951366
View directory record Official record
Conditions
Bronchopulmonary Disease
Interventions
Patient Registry
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2099
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 22, 2026, 4:30 AM EDT
Terminated Not applicable Interventional Results available

Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women

NCT03715530
View directory record Official record
Conditions
Preterm Labor, Preterm Birth
Interventions
PAMG-1 immunoassay
Device
Lead sponsor
Mark Santillan
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nourishing Beginnings: Addressing Food Insecurity During Pregnancy

NCT05341960
View directory record Official record
Conditions
Pregnancy Related, Food Insecurity, Premature Birth, Pregnancy Complications
Interventions
Food Delivery, Financial Support
Behavioral · Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older · Female only
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Not applicable Interventional Results available

Effect of Colostrum on Mucosal Immunity in Very Low Birth Weight (VLBWs) Premature Infants

NCT01776268
View directory record Official record
Conditions
Prematurity
Interventions
Oral priming
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 1 Year
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 22, 2026, 4:30 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Treatment of Chorioamnionitis After Delivery

NCT00814905
View directory record Official record
Conditions
Chorioamnionitis
Interventions
saline, ampicillin gentamicin, ampicillin gentamicin clindamycin
Drug
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 22, 2026, 4:30 AM EDT
Not yet recruiting Phase 2 Interventional

Pressure Targeting During High Flow Therapy in Premature Infants

NCT07418502
View directory record Official record
Conditions
Preterm Infants, Respiratory Distress Syndrome (Neonatal), BPD - Bronchopulmonary Dysplasia
Interventions
Pressure Targeted High Flow, CPAP
Procedure
Lead sponsor
University of Texas at Austin
Other
Eligibility
7 Days to 40 Weeks
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Diego, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 22, 2026, 4:30 AM EDT
Completed No phase listed Observational

Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes

NCT01975792
View directory record Official record
Conditions
Women Admitted to Labor and Delivery for the Management of Preterm Labor and/or Preterm Premature Rupture of Membranes (PPROM)
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Not applicable Interventional Results available

Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function

NCT04295564
View directory record Official record
Conditions
Neonatal, Premature Birth, Respiratory Distress Syndrome
Interventions
Additional 2 weeks of CPAP
Other
Lead sponsor
Cynthia McEvoy
Other
Eligibility
1 Day to 12 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 22, 2026, 4:30 AM EDT
Withdrawn Not applicable Interventional

Vaginal Progesterone as a Treatment for Women Active Preterm Labor

NCT01206998
View directory record Official record
Conditions
Labor, Premature
Interventions
Vaginal progesterone gel, Placebo vaginal gel
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2012 · Synced Oct 22, 2026, 4:30 AM EDT
Recruiting No phase listed Observational

Predictive Value of Lung Ultrasound for Respiratory Decompensation in Late Preterm Neonates

NCT07216053
View directory record Official record
Conditions
Pre-Term, Respiratory Distress of Newborn, Premature
Interventions
Point of care lung ultrasound
Diagnostic Test
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
34 Weeks to 36 Weeks
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preemie Prep For Parents (P3): Home Antenatal Prematurity Education

NCT04093492
View directory record Official record
Conditions
Premature Birth, Decision Making, Prenatal Care, Resuscitation, Infant, Premature
Interventions
Preemie Prep for Parents (P3) Outpatient Mobile Intervention, ACOG links
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Not listed
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Antenatal Micronutrient Supplementation and Infant Survival

NCT00860470
View directory record Official record
Conditions
Infant Mortality, Preterm Birth, Low Birth Weight, Neonatal Mortality, Perinatal Mortality
Interventions
Iron (27 mg) - folic acid (600 ug), Multiple micronutrient
Dietary Supplement
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
12 Years to 45 Years · Female only
Enrollment
44,567 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Phase 3 Interventional Results available

Comparison of Aerosol Delivery of Infasurf to Usual Care in Spontaneously Breathing RDS Patients

NCT03058666
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Aerosolized Calfactant, Solarys
Drug · Device
Lead sponsor
ONY
Industry
Eligibility
1 Hour to 24 Hours
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
22
States / cities
Mobile, Alabama • Phoenix, Arizona • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 22, 2026, 4:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Virtual Patient Advocate for Preconception Care for African American Women

NCT01812824
View directory record Official record
Conditions
Preconception Care
Interventions
Intervention (Virtual Patient Advocate)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2017 · Synced Oct 22, 2026, 4:30 AM EDT