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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:45 AM EDT

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Showing 433–456 of 806 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pre Term Labor Clear all
Completed No phase listed Observational Accepts healthy volunteers

Development of Standards for the New Ballard Maturation Score

NCT01203449
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Pregnancy
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
1,090 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 1996
U.S. locations
11
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Presenting Survival Information as Text or Pictograph During Periviable Birth Counseling

NCT04859114
View directory record Official record
Conditions
Premature Birth
Interventions
Format of outcome data presentation, Displayed chance of survival
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,052 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 24, 2023 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Not applicable Interventional

Parent Training for Parents of Toddlers Born Very Premature:

NCT05217615
View directory record Official record
Conditions
Parenting, Problem Behavior, Premature Birth, Parenting Intervention
Interventions
ezParent, Coaching calls, Active Control
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
20 Months and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 23, 2026, 8:45 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor

NCT00306462
View directory record Official record
Conditions
Premature Birth, Premature Labor
Interventions
Magnesium sulfate, Oral Nifedipine or placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2009 · Synced Oct 23, 2026, 8:45 AM EDT
Withdrawn No phase listed Observational

Hypercapnia and Its Association With Long-term Respiratory Morbidities in Premature Infants With Chronic Lung Disease

NCT02996162
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Massimo Root Monitoring System, ISA-Infrared Sidestream Gas Analyzer
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Days to 1 Year
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 23, 2026, 8:45 AM EDT
Not listed Not applicable Interventional

PREMOD2 With Near Infrared Spectroscopy Sub-study

NCT03145142
View directory record Official record
Conditions
Hypoxia, Brain, Premature Birth
Interventions
Umbilical cord milking, Delayed Cord Clamping
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome

NCT02477423
View directory record Official record
Conditions
Premature Birth of Newborn, Enterocolitis, Necrotizing
Interventions
Ampicillin, Gentamicins, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
Up to 6 Hours
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Phase 3 Interventional Results available

Surfactant Positive Airway Pressure and Pulse Oximetry Trial

NCT00233324
View directory record Official record
Conditions
Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
Interventions
Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%, Supplemental oxygen with target saturation of 91 to 95%
Drug · Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
24 Weeks to 27 Weeks
Enrollment
1,316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2016
U.S. locations
22
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 23, 2026, 8:45 AM EDT
Completed No phase listed Observational

The Neu-Prem Trial: Neuromonitoring of Preterm Newborn Brain During Birth Resuscitation

NCT02605733
View directory record Official record
Conditions
Neurologic Manifestations, Premature Birth, Hypoxia-Ischemia, Brain
Interventions
EEG, NIRS
Device
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 72 Hours
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 23, 2026, 8:45 AM EDT
Recruiting Not applicable Interventional

Maternal Stress on Human Milk and Infant Outcomes

NCT04821544
View directory record Official record
Conditions
Postpartum Depression, Preterm Labor
Interventions
Mindfulness-based intervention (with a focus on self-compassion; MBSC), Vitamin D
Behavioral · Dietary Supplement
Lead sponsor
University of Idaho
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Coeur d'Alene, Idaho
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Feasibility of Integrating Maternal Nutrition Interventions Into an Existing MNCH Platform in Bangladesh

NCT02745249
View directory record Official record
Conditions
Poor Fetal Growth, Small-for-gestational Age, Premature Birth
Interventions
Maternal Nutrition Behavior change
Behavioral
Lead sponsor
International Food Policy Research Institute
Other
Eligibility
18 Years to 45 Years
Enrollment
3,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Oct 23, 2026, 8:45 AM EDT
Recruiting Not applicable Interventional

Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey

NCT06822647
View directory record Official record
Conditions
Cervical Insufficiency, Preterm Birth, Cervical Length Measurement
Interventions
Cervical Length Measurement at the Beginning of the Anatomy Survey, Cervical Length Measurement at the End of the Anatomy Survey
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
Female only
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Not applicable Interventional

Donor Human Milk and Neurodevelopmental Outcomes in Very Low Birthweight (VLBW) Infants

NCT01232725
View directory record Official record
Conditions
Neurodevelopmental Outcomes of VLBW Infants
Interventions
Donor Human Milk
Dietary Supplement
Lead sponsor
Tarah T Colaizy
Other
Eligibility
Up to 24 Months
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 4, 2017 · Synced Oct 23, 2026, 8:45 AM EDT
Terminated Phase 4 Interventional

Metformin and Esomeprazole in Preterm Pre-eclampsia

NCT06359015
View directory record Official record
Conditions
Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
Interventions
Metformin, Esomeprazole
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 23, 2026, 8:45 AM EDT
Completed No phase listed Observational

Maternal Oral Therapy to Reduce Obstetric Risk Kids

NCT03423836
View directory record Official record
Conditions
Periodontitis, Autism, Premature Infants
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
1 Day and older
Enrollment
331 participants
Timeline
2007 – 2013
U.S. locations
4
States / cities
Birmingham, Alabama • Chapel Hill, North Carolina • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 23, 2026, 8:45 AM EDT
Active, not recruiting Phase 3 Interventional

Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes

NCT06273891
View directory record Official record
Conditions
Premature Rupture of Membrane
Interventions
Erythromycin, Azithromycin
Drug
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Falls Church, Virginia • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 23, 2026, 8:45 AM EDT
Completed No phase listed Observational

Evaluating Patterned Oral Somatosensory Entrainment Stimulation Using the NTrainer on Oral Feeding Performance

NCT01069718
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
KC BioMediX, Inc
Industry
Eligibility
34 Weeks to 18 Months
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2010 · Synced Oct 23, 2026, 8:45 AM EDT
Recruiting No phase listed Observational

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

NCT05336890
View directory record Official record
Conditions
Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
Interventions
Not listed
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
30 Weeks to 83 Months
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 23, 2026, 8:45 AM EDT
Not listed Not applicable Interventional

Cerclage for Twins With Short Cervical Length ≤ 15mm

NCT03340688
View directory record Official record
Conditions
Twin Pregnancy With Antenatal Problem, Preterm Birth, Short Cervix
Interventions
Cervical cerclage
Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Philadelphia, Pennsylvania • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 23, 2026, 8:45 AM EDT
Completed No phase listed Observational

Assessment of Pain in Newborns and Older Infants (Infant Pain Assessment Study =

NCT03330496
View directory record Official record
Conditions
Pain, Acute
Interventions
Pain Measurement
Other
Lead sponsor
Stanford University
Other
Eligibility
1 Day to 6 Months
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Oct 23, 2026, 8:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Lung Structure and Function of Infants Born Prematurely

NCT00422305
View directory record Official record
Conditions
Premature Birth, Bronchopulmonary Dysplasia, Asthma
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
2 Months to 36 Months
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Delayed Cord Clamping in VLBW Infants

NCT01222364
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Standard Cord Clamping, Delayed Cord Clamping
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
0 Minutes to 1 Minute
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000
U.S. locations
4
States / cities
Birmingham, Alabama • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mentors Offering Maternal Support (M-O-M-S™): A Prenatal Program for Decreasing Maternal Anxiety and Depression

NCT03393637
View directory record Official record
Conditions
Anxiety Fear, Prenatal Depression, Infant, Low Birth Weight, Preterm Birth, Maternal
Interventions
Mentors Offering Maternal Support (M-O-M-S)
Behavioral
Lead sponsor
University of the Incarnate Word
Other
Eligibility
18 Years and older · Female only
Enrollment
1,717 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
3
States / cities
San Diego, California • San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced Oct 23, 2026, 8:45 AM EDT
Completed Not applicable Interventional

The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants

NCT03836430
View directory record Official record
Conditions
Postpartum Depression, Preterm Infant, Infant Development
Interventions
Newborn Behavioral Observation-Family Wellness (NBO-FW)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2022 · Synced Oct 23, 2026, 8:45 AM EDT