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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:44 PM EDT

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Showing 385–408 of 729 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pre-Diabetes Clear all
Completed Not applicable Interventional Results available

Acute Exercise Effects in Obese Pregnancy

NCT03750695
View directory record Official record
Conditions
Pregnancy Complications, Obesity, Pre-Eclampsia, Gestational Diabetes
Interventions
Resistance exercise, Aerobic Exercise, Rest
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 21, 2026, 4:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome

NCT02122666
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
muscle biopsy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 26, 2024 · Synced Oct 21, 2026, 4:44 PM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Growth Hormone Resistance of Beta-cells

NCT07581860
View directory record Official record
Conditions
Healthy, Obesity & Overweight, Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (Prediabetes)
Interventions
Not listed
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 59 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 21, 2026, 4:44 PM EDT
Completed No phase listed Observational

Gender Differences in Prevalence of Undiagnosed Diabetes in ACS

NCT00589459
View directory record Official record
Conditions
Pre-diabetes, Diabetes
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
30 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
2
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 21, 2026, 4:44 PM EDT
Terminated Not applicable Interventional Results available

Heat Shock Therapy to Improve Mitochondrial Function in Neuropathy

NCT05070741
View directory record Official record
Conditions
PreDiabetes, Neuropathy
Interventions
Heat Therapy
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Not applicable Interventional

Transition of Diabetes Care From Pediatric to Adult Healthcare Providers.

NCT03844126
View directory record Official record
Conditions
Transition
Interventions
Transition classes
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
16 Years to 21 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 24, 2020 · Synced Oct 21, 2026, 4:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Noninvasive Transcutaneous Glucometer Development

NCT01168076
View directory record Official record
Conditions
Healthy, Prediabetic State (IGT), Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Interventions
Not listed
Lead sponsor
InLight Solutions
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 22, 2010 · Synced Oct 21, 2026, 4:44 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Social Determinants and a Diabetes Prevention Program Tailored for African Americans

NCT05301413
View directory record Official record
Conditions
PreDiabetes, Overweight and Obesity
Interventions
Culturally Tailored Diabetes Prevention Program, Culturally Tailored DPP Enhanced with Socioeconomic Supports, Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 21, 2026, 4:44 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Vascular Function, Endothelin, and Inflammation in Pre-diabetic Obesity Versus Lean Healthy Controls

NCT00837590
View directory record Official record
Conditions
Pre-diabetes, Obesity
Interventions
Chronic salsalate, Acute Salsalate
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PASO A PASO: Tailored Diabetes Prevention Program for Spanish-Speaking Communities Feasibility Study

NCT07392008
View directory record Official record
Conditions
Pre Diabetic
Interventions
Paso a Paso
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 4:44 PM EDT
Active, not recruiting Not applicable Interventional

Randomized Trial of Exercise Promotion in Primary Care

NCT04445168
View directory record Official record
Conditions
PreDiabetes, Diabetes, Sedentary Behavior
Interventions
Telephone-based motivational interviews
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 74 Years
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Carbohydrate Drink in Adults

NCT04313920
View directory record Official record
Conditions
Glycemic Response
Interventions
Nutritional Supplement
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
18 Years to 75 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
3
States / cities
Jupiter, Florida • Addison, Illinois • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Oct 21, 2026, 4:44 PM EDT
Terminated Phase 2 Interventional Results available

Interventional Bioremediation of Microbiota in Metabolic Syndrome

NCT02730962
View directory record Official record
Conditions
Pre-Diabetes
Interventions
Vancomycin, Placebo, Neomycin, Clindamycin, Fecal Microbiota Transplantation
Drug · Other · Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 21, 2026, 4:44 PM EDT
Not listed Not applicable Interventional

Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting

NCT04564586
View directory record Official record
Conditions
PreDiabetes, Metabolic Syndrome, Protection Against
Interventions
DPPFit
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Oct 21, 2026, 4:44 PM EDT
Recruiting Not applicable Interventional

Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial

NCT06365723
View directory record Official record
Conditions
PreDiabetes, Heart Rate Variability (HRV), Stress and Anxiety, Stress Biomarkers
Interventions
Nature-based Walking, Built-environment/Commercial Walking
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
25 Years to 64 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Lake Forest, Illinois • Winfield, Illinois • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Not applicable Interventional

Automated Diabetes Prevention Program

NCT00384488
View directory record Official record
Conditions
Pre-Diabetes
Interventions
Interactive Voice Response System (IVR)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 6, 2006 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Not applicable Interventional

Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes

NCT02000024
View directory record Official record
Conditions
Prediabetes, Gestational Diabetes Mellitus, Obesity
Interventions
Weight Watchers, National Diabetes Education Program
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 8, 2016 · Synced Oct 21, 2026, 4:44 PM EDT
Terminated Early Phase 1 Interventional

Brain Imaging in the Diabetes Prevention Program Outcomes Study

NCT03757910
View directory record Official record
Conditions
Alzheimer Disease
Interventions
18F-MK-6240, 11C-PIB
Drug
Lead sponsor
José A. Luchsinger
Other
Eligibility
60 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Oct 21, 2026, 4:44 PM EDT
Recruiting Not applicable Interventional

Risk-informed Shared-decision Making Engagement Strategy for Patients With Prediabetes

NCT07553325
View directory record Official record
Conditions
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Interventions
Risk Informed Shared Decision-Making Strategy (RISE), Low Touch Messaging Strategy (LTM)
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Frederick, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 21, 2026, 4:44 PM EDT
Recruiting Not applicable Interventional

Heat and Exercise in Aging as Therapy (HEAT)

NCT06580964
View directory record Official record
Conditions
Prediabetic State
Interventions
Heat therapy, High-intensity interval training
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
50 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fit and Trim for Diabetes Prevention

NCT02278939
View directory record Official record
Conditions
Pre-diabetes, Overweight, Obese
Interventions
Filipinos Fit and Trim Weight Loss Program
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
24 Years to 80 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Phase 1Phase 2 Interventional

We Can Prevent Diabetes: A Behavioral Intervention to Reduce Diabetes Risk in African Americans

NCT01227473
View directory record Official record
Conditions
Prediabetes
Interventions
Mindfulness-based diabetes prevention education group, Conventional diabetes prevention education group
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
25 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2012 · Synced Oct 21, 2026, 4:44 PM EDT
Not yet recruiting Phase 1 Interventional

Human Models of Selective Insulin Resistance: Pancreatic Clamp

NCT06558422
View directory record Official record
Conditions
Insulin Resistance, Hyperinsulinemia, Metabolic Dysfunction Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease, Prediabetic State, Obesity
Interventions
Insulin human, Octreotide Acetate, Glucagon, Growth Hormone, Human, 20% D-glucose (aq), [6,6-2H2] D-glucose, [1-13C1] sodium acetate, Nestle BOOST Plus, KIND Bar, Harvard Apparatus PHD ULTRA CP syringe pump, Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer
Drug · Diagnostic Test · Dietary Supplement + 1 more
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 21, 2026, 4:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease

NCT01884545
View directory record Official record
Conditions
Coronary Heart Disease, Susceptibility to, 5, Prediabetic State
Interventions
Health coaching, Genetic risk counseling, Standard risk assessment
Behavioral · Genetic
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Fairfield, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Oct 21, 2026, 4:44 PM EDT