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ClinicalTrials.gov public records Last synced Sep 8, 2026, 4:53 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pre-Diabetic Clear all
Recruiting No phase listed Observational

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

NCT05799222
View directory record Official record
Conditions
Overweight, PreDiabetes, Diabetes Type 2, Obesity
Interventions
Bariatrix Meal Replacement Products
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Enhancing Fitness in Older Pre-diabetic Veterans

NCT00594399
View directory record Official record
Conditions
Impaired Glucose Tolerance, Obesity, Diabetes
Interventions
Physical Activity Counseling
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2015 · Synced Sep 8, 2026, 4:53 PM EDT
Active, not recruiting Not applicable Interventional

Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial

NCT06976307
View directory record Official record
Conditions
Disabilities, Obesity and Overweight, Prediabetes
Interventions
High Carbohydrate Diet, Reduced Carbohydrate Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 8, 2026, 4:53 PM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients

NCT02496780
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
novolog insulin, levemir insulin, placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
10 Years to 25 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional

The Avoiding Diabetes Thru Action Plan Targeting Pilot Randomized Control Trial

NCT01473654
View directory record Official record
Conditions
Prediabetes
Interventions
ADAPT tool
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2014 · Synced Sep 8, 2026, 4:53 PM EDT
Recruiting Phase 4 Interventional

Effect of Zinc on Glucose Homeostasis

NCT05835037
View directory record Official record
Conditions
Prediabetic State, Hyperglycemia
Interventions
Zinc Gluconate 30 MG, Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Finding the Patient's Voice Diabetes Prevention Programs

NCT02700503
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Prediabetic State
Interventions
Encourage 2.0
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
10 Years to 18 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Phase 4 Interventional Results available

GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response

NCT04387201
View directory record Official record
Conditions
Glucose Intolerance, Overweight and Obesity, Drug Effect, Adiposity
Interventions
Cyanocobalamin, Dulaglutide
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Phase 2 Interventional Results available

A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women

NCT01877564
View directory record Official record
Conditions
Adenocarcinoma of the Endometrium
Interventions
Metformin
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional Results available

Behavior Change Intervention for Cardiovascular Risk Reduction Among People Experiencing Homelessness

NCT06025721
View directory record Official record
Conditions
Heart Diseases, Diabetes Mellitus, Type 2, Pre-diabetes, Hypertension, Hyperlipidemias
Interventions
Cardiovascular Risk Homeless Support
Behavioral
Lead sponsor
Katherine Vickery
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Integrating Cultural Aspects Into Diabetes Education

NCT05492916
View directory record Official record
Conditions
PreDiabetes
Interventions
Diabetes Prevention Program (DPP), Community-Supported Agriculture (CSA), Community Health Worker support (CHW)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 8, 2026, 4:53 PM EDT
Recruiting Not applicable Interventional

Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes

NCT07131384
View directory record Official record
Conditions
Males, Females, Sedentary, Metformin, Prediabetes
Interventions
Dietary Supplement: Inorganic Nitrate (Beetroot juice), Dietary supplement: Placebo (Nitrate-depleted beetroot juice)
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 8, 2026, 4:53 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care

NCT04869917
View directory record Official record
Conditions
PreDiabetes
Interventions
Decision Aid intervention, Text Messaging intervention, Usual Care
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients

NCT02551640
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Prediabetic State, Hypertension, Prehypertension, Obesity
Interventions
FeatForward App (on study smartphone)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Charlestown, Massachusetts • Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Sep 8, 2026, 4:53 PM EDT
Completed No phase listed Observational

Diabetes PRP and OCT

NCT01928550
View directory record Official record
Conditions
Proliferative Diabetic Retinopathy
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 8, 2018 · Synced Sep 8, 2026, 4:53 PM EDT
Recruiting Phase 3 Interventional

Vitamin D and Type 2 Diabetes - Treat-To-Target

NCT07448974
View directory record Official record
Conditions
Prediabetes, Type 2 Diabetes (T2DM)
Interventions
Vitamin D (Cholecalciferol ), Placebo
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
30 Years to 74 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin

NCT02330276
View directory record Official record
Conditions
Pre-diabetes
Interventions
(+)-Epicatechin
Drug
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
21 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Physical Activity and Obesity

NCT02060240
View directory record Official record
Conditions
Obesity, Prediabetic State, Sedentary Lifestyle
Interventions
High Activity
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
30 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Sep 8, 2026, 4:53 PM EDT
Recruiting No phase listed Observational

This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder

NCT07804680
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome, Prediabetes
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
6 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RCT of a Polyherbal Dietary Supplement for Prediabetes

NCT03388762
View directory record Official record
Conditions
Prediabetic State
Interventions
GlucoSupreme™ Herbal, Placebo
Dietary Supplement · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
4
States / cities
Baltimore, Maryland • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Sep 8, 2026, 4:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Insulin Resistance and Endometrial Cancer in Harris County, Texas

NCT00495235
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
8
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Sep 8, 2026, 4:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth

NCT00536250
View directory record Official record
Conditions
Impaired Glucose Tolerance, Pre-diabetes, Childhood Obesity, Insulin Resistance, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
8 Years to 22 Years
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional Results available

Diabetes Prevention Program Feasibility Study of Breastfeeding

NCT04021602
View directory record Official record
Conditions
Pregnancy, Overweight and Obesity
Interventions
Diabetes Prevention Program, Breastfeeding Education, Usual Care
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Lakin, Kansas • Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 8, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial

NCT03640286
View directory record Official record
Conditions
Obesity
Interventions
VeSTAL
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
La Jolla, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 8, 2026, 4:53 PM EDT