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Showing 1–24 of 355 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pre-Hypertension Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Multi-Omics for Maternal Health After Preeclampsia

NCT06340152
View directory record Official record
Conditions
Pre-Eclampsia, Pregnancy Induced Hypertension
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Phase 3 Interventional

Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1)

NCT00093249
View directory record Official record
Conditions
Hypertension
Interventions
clevidipine, placebo
Drug
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • Hudson, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2014 · Synced Jul 22, 2026, 2:11 AM EDT
Completed No phase listed Observational

sFlt-1:PlGF Ratio in Diagnosing Superimposed Preeclampsia

NCT03441711
View directory record Official record
Conditions
Preeclampsia
Interventions
Not listed
Lead sponsor
University of Tennessee
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Jul 22, 2026, 2:11 AM EDT
Not yet recruiting No phase listed Observational

Gestational Changes in Hemodynamics and Respiratory Mechanics in Association With Pre-Eclampsia

NCT07695909
View directory record Official record
Conditions
Pre-eclampsia, Pregnancy, Post Partum
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Destiffening and Hypotensive Effects of Whole Milk and Full-fat Dairy Products

NCT02397902
View directory record Official record
Conditions
Hypertension, Prehypertension
Interventions
High fat dairy, Plant-based
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
20 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Jul 22, 2026, 2:11 AM EDT
Terminated Phase 3 Interventional Results available

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

NCT03298802
View directory record Official record
Conditions
Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced, Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Interventions
Hydrochlorothiazide 50mg Tablet, Placebo Tablet
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
2
States / cities
Austin, Texas • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Remote Monitoring and Follow-up for Postpartum Hypertensive Disorders of Pregnancy

NCT05124327
View directory record Official record
Conditions
Hypertensive Disorder of Pregnancy, Preeclampsia, Gestational Hypertension
Interventions
QI project- usage of RPM
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Jul 22, 2026, 2:11 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preeclampsia Research on Vitamin D, Inflammation, & Depression

NCT03018132
View directory record Official record
Conditions
Pre-Eclampsia, Depression, Inflammation, Vitamin D Deficiency
Interventions
mental health screening, education and referral program
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Jul 22, 2026, 2:11 AM EDT
Enrolling by invitation No phase listed Observational

Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines

NCT06576544
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication, Postpartum Pre-Eclampsia, Cardiovascular Diseases, Cardiovascular Morbidity, Morbidity;Perinatal
Interventions
BP Watch
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Jul 22, 2026, 2:11 AM EDT
Completed No phase listed Observational

Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification

NCT03815110
View directory record Official record
Conditions
Preeclampsia and Eclampsia, Preeclampsia Severe, Gestational Hypertension, Chronic Hypertension in Obstetric Context, Superimposed Pre-Eclampsia, Preeclampsia Mild
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
18
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 13 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2022 · Synced Jul 22, 2026, 2:11 AM EDT
Recruiting Phase 4 Interventional

Treatment With Aspirin After Preeclampsia: TAP Trial

NCT06281665
View directory record Official record
Conditions
Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia, Gestational Hypertension, Cardiovascular Diseases, Toxemia, Pregnancy Complications, Vascular Diseases, Hypertension, Pregnancy Induced, Hypertension;Pre-Eclamptic
Interventions
Low-dose aspirin, Placebo
Drug
Lead sponsor
Malamo Countouris
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Abbreviated MgSO4 Therapy in Post-partum Preeclampsia

NCT00344058
View directory record Official record
Conditions
Pregnancy, Preeclampsia
Interventions
abbreviation of magnesium sulfate therapy (12 hours versus the traditional 24 hours after delivery)
Drug
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Jul 22, 2026, 2:11 AM EDT
Completed No phase listed Observational

Bedside Monitoring to Identify Impaired Cerebral Autoregulation in Women with Postpartum Hypertension

NCT05155852
View directory record Official record
Conditions
Preeclampsia, Hypertension in Pregnancy
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2024 · Synced Jul 22, 2026, 2:11 AM EDT
Not yet recruiting Phase 3 Interventional

Levetiracetam Compared to Magnesium Sulfate for Prevention of Eclamptic Seizure

NCT07220902
View directory record Official record
Conditions
Severe Preeclampsia, Eclampsia Preeclampsia
Interventions
Levetiracetam, magnesium sulfate
Drug
Lead sponsor
Nebraska Methodist Health System
Other
Eligibility
19 Years and older · Female only
Enrollment
1,240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2034
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Stanford Clinics Physician Mindset Training

NCT03677609
View directory record Official record
Conditions
Diabetes, Diabetes Mellitus, Hypertension, Pre Diabetes, Overweight and Obesity
Interventions
Mindset & Communication Training
Behavioral
Lead sponsor
Kari Alyse Leibowitz
Other
Eligibility
18 Years and older
Enrollment
78,128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Jul 22, 2026, 2:11 AM EDT
Completed No phase listed Observational

Antenatal Platelet Response On Aspirin and Correlation With HDP (Hypertensive Disorders of Pregnancy)

NCT04295850
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin 81 mg
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
10 Years to 60 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 22, 2026, 2:11 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Physical Activity to Mitigate PreEclampsia Risk

NCT06319014
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
Exercise Modes
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Online CBT-I for High Blood Pressure

NCT02299193
View directory record Official record
Conditions
Hypertension, Prehypertension, Insomnia
Interventions
Cognitive Behavioral Therapy, Healthy Sleep Habits
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 30, 2016 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Blood Pressure in Prehypertensive Older Rural Women Also Known as Wellness for Women: DASHing Toward Health

NCT00580528
View directory record Official record
Conditions
Pre-Hypertension
Interventions
Tailored Internet Newsletters, Tailored print newsletters delivered via mail
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
40 Years to 69 Years · Female only
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Jul 22, 2026, 2:11 AM EDT
Terminated Not applicable Interventional

Ambrisentan for the Improvement in Right Ventricular Strain in Scleroderma Associated Pulmonary Arterial Hypertension

NCT02169752
View directory record Official record
Conditions
Pre-Pulmonary Atrial Hypertension
Interventions
Ambrisentan
Drug
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 18, 2021 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chronic Cardiovascular Risk Outpatient Management in South Asians Using Digital Health Technology

NCT03167996
View directory record Official record
Conditions
Cardiovascular Risk Factor, Insulin Resistance, PreDiabetes, Diabetes, Coronary Artery Disease, Hypertension, Prehypertension, Dyslipidemias
Interventions
Use of HealthPals (Telemedicine supported by digital health platform)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Modernized Approach to Prenatal Care in Low Risk Women

NCT01606774
View directory record Official record
Conditions
Pre-eclampsia, Intrauterine Growth Retardation
Interventions
Modernized prenatal care
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Up to 35 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Jul 22, 2026, 2:11 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Wald Outreach for Wellness: Blood Pressure Outreach

NCT04286568
View directory record Official record
Conditions
Pre-hypertension, Hypertension
Interventions
WOW Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jul 22, 2026, 2:11 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Study of Amiloride on Vascular Phenotypes in Young Adults With Prehypertension

NCT01308983
View directory record Official record
Conditions
Prehypertension
Interventions
Amiloride
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 35 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 22, 2012 · Synced Jul 22, 2026, 2:11 AM EDT