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ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:48 AM EDT

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Showing 217–240 of 1,452 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pre-Term Clear all
Completed No phase listed Observational

ROP Check Database Premature Infant Outcomes

NCT07312669
View directory record Official record
Conditions
Retinopathy of Prematurity (ROP)
Interventions
Not listed
Lead sponsor
Alaska Blind Child Discovery
Other
Eligibility
Not listed
Enrollment
7,070 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Dec 31, 2025 · Synced Oct 22, 2026, 5:48 AM EDT
Not yet recruiting Not applicable Interventional

The Goal is to Examine the Impact of Doula-coordinated, Midwife-delivered Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.

NCT07787845
View directory record Official record
Conditions
Doula Support, Postpartum, Postpartum Anaemia, Postpartum Depression (PPD)
Interventions
Doula-coordinated, Midwife-delivered postpartum care
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Postpartum Contraception in Women With Preterm Births

NCT01864629
View directory record Official record
Conditions
Method of Contraception, Preterm Birth Recurrence
Interventions
Focused contraception counseling
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
14 Years to 50 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 22, 2026, 5:48 AM EDT
Terminated Not applicable Interventional

Randomized Controlled Trial of Surfactant Administration by Laryngeal Mask Airway (LMA)

NCT00599651
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Surfactant administered via Laryngeal Mask Airway (LMA), standard of care (nasal CPAP and supplemental oxygen)
Device · Other
Lead sponsor
University of Virginia
Other
Eligibility
Up to 72 Hours
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 7, 2010 · Synced Oct 22, 2026, 5:48 AM EDT
Active, not recruiting No phase listed Observational

MIRACLE of LIFE Study

NCT06074601
View directory record Official record
Conditions
Preterm Labor, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane, Preeclampsia, HELLP, Gestational Hypertension, Gestational Diabetes Mellitus in Pregnancy, Small for Gestational Age at Delivery, Intrauterine Growth Restriction
Interventions
Mirvie Predictive Test for Adverse Pregnancy Outcomes
Diagnostic Test
Lead sponsor
Mirvie
Industry
Eligibility
18 Years and older · Female only
Enrollment
10,000 participants
Timeline
2021 – 2025
U.S. locations
10
States / cities
San Diego, California • Orlando, Florida • New Orleans, Louisiana + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 22, 2026, 5:48 AM EDT
Recruiting Not applicable Interventional

Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial

NCT06420531
View directory record Official record
Conditions
Prematurity
Interventions
Human milk
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
6 Hours to 4 Days
Enrollment
486 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
4
States / cities
Birmingham, Alabama • Jackson, Mississippi • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 22, 2026, 5:48 AM EDT
Recruiting Not applicable Interventional

How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants

NCT07674953
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Respiratory Distress of Newborn
Interventions
Effective oxygen delivery and lung expansion measurement
Device
Lead sponsor
University of Arkansas
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 22, 2026, 5:48 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Growth Observational Study

NCT01203475
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 24 Hours
Enrollment
1,660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 1995
U.S. locations
13
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 22, 2026, 5:48 AM EDT
Completed No phase listed Observational

Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus

NCT03551600
View directory record Official record
Conditions
Infant, Premature, Congenital Heart Disease, Patent Ductus Arteriosus, Necrotizing Enterocolitis
Interventions
Near-infrared spectroscopy (NIRS)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
12 Days to 6 Months
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Oct 22, 2026, 5:48 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Inhaled Nitric Oxide and Neuroprotection in Premature Infants

NCT00515281
View directory record Official record
Conditions
Prematurity, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Periventricular Leukomalacia
Interventions
inhaled nitric oxide, oxygen
Drug
Lead sponsor
University of Chicago
Other
Eligibility
2 Hours to 72 Hours
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing IM vs. Vaginal Progesterone for Pre-term Birth

NCT00579553
View directory record Official record
Conditions
Infant, Premature, Premature Birth
Interventions
Intramuscular Progesterone, Vaginal Progesterone
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Oct 22, 2026, 5:48 AM EDT
Completed No phase listed Observational

Neurotrophin Expression in Infants as a Predictor of Respiratory and Neurodevelopmental Outcomes

NCT03373539
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Chronic Lung Disease
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
1 Day to 4 Months
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Phase 1 Interventional

Is Skin-to-Skin Care Helpful for Preterm Infants and Their Mothers After Birth?

NCT00917085
View directory record Official record
Conditions
Moderate to Late Prematurity
Interventions
Skin-to-Skin contact
Behavioral
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2001
U.S. locations
2
States / cities
Cleveland, Ohio • Richmond, Washington
Source: ClinicalTrials.gov public record
Updated Aug 10, 2009 · Synced Oct 22, 2026, 5:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

NCT03906435
View directory record Official record
Conditions
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Not applicable Interventional

Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants

NCT00875758
View directory record Official record
Conditions
Intraventricular Hemorrhage, Hydrocephalus
Interventions
Removal of CSF through ventricular access device, Removal of CSF through a ventricular access device
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 34 Weeks
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 22, 2026, 5:48 AM EDT
Completed No phase listed Observational

Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development

NCT02639676
View directory record Official record
Conditions
Preeclampsia
Interventions
Diffusion Lung Capacity (DLCO), Vascular Challenge, Video Imaging, Specimen Collections
Other
Lead sponsor
Indiana University
Other
Eligibility
26 Weeks and older
Enrollment
292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Oct 22, 2026, 5:48 AM EDT
Completed No phase listed Observational

Evaluating Decisional Regret Among Mothers

NCT04074525
View directory record Official record
Conditions
Extreme Prematurity, Birth, Preterm, Pregnancy Preterm
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older · Female only
Enrollment
211 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Phase 2 Interventional

Early Protein Supplementation of Human Milk in Extremely Low Birth Weight Infants

NCT01991613
View directory record Official record
Conditions
Growth in Premature Infants
Interventions
liquid protein supplement
Dietary Supplement
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
26 Weeks to 33 Weeks
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 22, 2026, 5:48 AM EDT
Completed No phase listed Observational

Effective Fraction of Inspired Oxygen With Nasal Cannula in Premature Infants

NCT03431818
View directory record Official record
Conditions
Oxygen Therapy
Interventions
Nasal cannula flow rate
Other
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Not applicable Interventional

VentFirst Pilot: Ventilating Preterm Infants During Delayed Cord Clamping

NCT02391389
View directory record Official record
Conditions
Infant, Premature, Diseases
Interventions
CPAP or PPV during DCC
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Phase 2 Interventional Results available

Safety of Sildenafil in Premature Infants

NCT03142568
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Sildenafil, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Days to 28 Days
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
14
States / cities
Little Rock, Arkansas • Jacksonville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 22, 2026, 5:48 AM EDT
Active, not recruiting Phase 3 Interventional

Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes

NCT06273891
View directory record Official record
Conditions
Premature Rupture of Membrane
Interventions
Erythromycin, Azithromycin
Drug
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Falls Church, Virginia • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 22, 2026, 5:48 AM EDT
Withdrawn Not applicable Interventional

Use of Prokinetics in Early Enteral Feeding in Preterm Infants

NCT01569633
View directory record Official record
Conditions
Feeding Disorder, Nutrition Disorder, Infant,Premature
Interventions
Metclopramide, Erythromycin, placebo
Drug
Lead sponsor
East Tennessee State University
Other
Eligibility
Up to 14 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 22, 2026, 5:48 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.

NCT00549211
View directory record Official record
Conditions
Obstetric Labour, Premature, Premature Ejaculation
Interventions
GSK557296
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
1
States / cities
Evansville, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 19, 2012 · Synced Oct 22, 2026, 5:48 AM EDT