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ClinicalTrials.gov public records Last synced Oct 25, 2026, 9:48 PM EDT

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Showing 673–696 of 1,452 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pre-Term Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban

NCT01826266
View directory record Official record
Conditions
Anticoagulant Reversal, Reversal of Edoxaban Induced Anticoagulation
Interventions
PER977, Placebo
Drug
Lead sponsor
Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Oct 25, 2026, 9:48 PM EDT
Completed No phase listed Observational

Comparison of Non-nutritive Suck (NNS) Measures to Clinical Estimates of Suck and Feeding Readiness in Preterm Infants

NCT01069731
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
KC BioMediX, Inc
Industry
Eligibility
30 Weeks to 36 Weeks
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2010 · Synced Oct 25, 2026, 9:48 PM EDT
Completed No phase listed Observational

Proteomic Assessment of Preterm Birth

NCT01371019
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Sera Prognostics, Inc.
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
5,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
13
States / cities
Phoenix, Arizona • San Diego, California • Newark, Delaware + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2015 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Not applicable Interventional

Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA

NCT03242057
View directory record Official record
Conditions
Preterm Infant, BPD - Bronchopulmonary Dysplasia, Barotrauma
Interventions
NAVA, NIPPV
Other
Lead sponsor
University of Florida
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Not applicable Interventional

Mild Preeclampsia Near Term: Deliver or Deliberate?

NCT00789919
View directory record Official record
Conditions
Preeclampsia
Interventions
Delivery of infant
Procedure
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Oct 25, 2026, 9:48 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Biomarkers Study in Infants With Prior Neonatal Brain Injury

NCT07413900
View directory record Official record
Conditions
HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury, Premature Birth, Healthy Participants
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
3 Months to 24 Months
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 25, 2026, 9:48 PM EDT
Not listed No phase listed Observational

The Accuracy of Amniotic Fluid Ferning in the Second Trimester in the Diagnosis of Preterm Prelabor Rupture of Membranes

NCT04963465
View directory record Official record
Conditions
Preterm Premature Rupture of Membrane, Amniotic Fluid Leakage
Interventions
Ferning on microscopy
Diagnostic Test
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 3 Interventional

Safe Passages: Ensuring Quality Transitions From NICU (Neonatal Intensive Care Unit) to Ambulatory Care

NCT01088945
View directory record Official record
Conditions
Infant, Premature, Diseases
Interventions
Enhanced Discharge process
Behavioral
Lead sponsor
Virginia Moyer
Other
Eligibility
Not listed
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2015 · Synced Oct 25, 2026, 9:48 PM EDT
Not listed Not applicable Interventional

Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates

NCT02445040
View directory record Official record
Conditions
Respiratory Distress Syndrome In Premature Infants
Interventions
Babylog VN500 in HFOV Mode
Device
Lead sponsor
Draeger Medical Systems, Inc.
Industry
Eligibility
23 Weeks to 30 Weeks
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
14
States / cities
Little Rock, Arkansas • San Diego, California • Iowa City, Iowa + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Oct 25, 2026, 9:48 PM EDT
Not listed Not applicable Interventional

Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping)

NCT03476980
View directory record Official record
Conditions
Neurodevelopmental Abnormality
Interventions
Randomized to Umbilical Cord Milking at birth, Randomized to Delayed Cord Clamping at birth
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
22 Months to 42 Months
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
15
States / cities
Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2022 · Synced Oct 25, 2026, 9:48 PM EDT
Terminated Not applicable Interventional Results available

Tortle Midliner and Intraventricular Hemorrhage

NCT03543046
View directory record Official record
Conditions
Intraventricular Hemorrhage of Prematurity
Interventions
Tortle Midliner
Device
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
Up to 31 Weeks
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 2, 2022 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 2 Interventional Results available

Ranolazine Mediated PVC Reduction in Ischemic Heart Disease

NCT02360397
View directory record Official record
Conditions
Ventricular Premature Complexes, Myocardial Ischemia
Interventions
ranolazine
Drug
Lead sponsor
Kent Hospital, Rhode Island
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 25, 2026, 9:48 PM EDT
Terminated Not applicable Interventional

PAL to Improve Oral Feeding for Infants With Chronic Lung Disease

NCT05446389
View directory record Official record
Conditions
Chronic Lung Disease of Prematurity, Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia, Preterm Birth
Interventions
Pacifier Activated Lullaby ®
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
1 Day to 33 Weeks
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Open-Label, Safety, and Efficacy Study of Dexmedetomidine in Preterm Subjects Ages ≥28 Weeks to <36 Weeks Gestational Age

NCT01508455
View directory record Official record
Conditions
Anesthesia
Interventions
Dexmedetomidine, Midazolam, Fentanyl, Morphine
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
28 Weeks to 36 Weeks
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
4
States / cities
Louisville, Kentucky • Pittsburgh, Pennsylvania • Greenville, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Oct 25, 2026, 9:48 PM EDT
Not listed Phase 2Phase 3 Interventional

Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease

NCT01721655
View directory record Official record
Conditions
Chronic Lung Disease, Bronchopulmonary Dysplasia
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
West Virginia University Healthcare
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 3 Interventional Results available

Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia

NCT02059135
View directory record Official record
Conditions
Preeclampsia
Interventions
Recombinant human antithrombin (ATryn), Normal Saline 0.9%
Biological · Other
Lead sponsor
rEVO Biologics
Industry
Eligibility
16 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
23
States / cities
Birmingham, Alabama • Mobile, Alabama • Little Rock, Arkansas + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2017 · Synced Oct 25, 2026, 9:48 PM EDT
Completed No phase listed Observational

39946-I Laser and Bevacizumab Treatment for Retinopathy of Prematurity

NCT01993043
View directory record Official record
Conditions
ROP Threshold
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
30 Weeks to 40 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
2
States / cities
Houston, Texas • Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 1Phase 2 Interventional

N-acetylcysteine in Intra-amniotic Infection/Inflammation

NCT00397735
View directory record Official record
Conditions
Labor, Premature, Preterm Premature Rupture of the Membranes, Infection, Inflammation, Chorioamnionitis
Interventions
amniocentesis, N-acetylcysteine or placebo
Procedure · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 25, 2026, 9:48 PM EDT
Active, not recruiting Not applicable Interventional Results available

Serial Assessment of Body Fat Accrual in Very Preterm Infants

NCT03575897
View directory record Official record
Conditions
Infant,Premature, Body Weight, Adiposity
Interventions
Assessment of infant body composition
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 14 Days
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 3 Interventional Results available

Hydrocortisone for BPD

NCT01353313
View directory record Official record
Conditions
Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature, Bronchopulmonary Dysplasia
Interventions
Hydrocortisone, Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 30 Weeks
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
20
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 25, 2026, 9:48 PM EDT
Completed No phase listed Observational

Psychological Effects of Bone Marrow Transplants in Children

NCT00645931
View directory record Official record
Conditions
Psychological
Interventions
protein and calorie controlled diet and self-hypnotic relaxation
Behavioral
Lead sponsor
Corewell Health West
Other
Eligibility
1 Day to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2023 · Synced Oct 25, 2026, 9:48 PM EDT
Recruiting Not applicable Interventional

Improving Outcomes in Early Menopause After Cancer

NCT06982677
View directory record Official record
Conditions
Early Menopause, Cancer, Premature Menopause, Surgical Menopause
Interventions
Nurse Navigator Intervention, Education Control
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 2 Interventional Results available

A Study To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Two Oral Doses of GSK557296 in a Study in Men With Premature Ejaculation

NCT01021553
View directory record Official record
Conditions
Premature Ejaculation
Interventions
GSK557296, placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
6
States / cities
San Diego, California • San Jose, California • Fort Wayne, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2017 · Synced Oct 25, 2026, 9:48 PM EDT
Completed Phase 3 Interventional Results available

Extension Study of Secukinumab Prefilled Syringes in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis Completing Preceding Psoriasis Phase III Studies With Secukinumab

NCT01544595
View directory record Official record
Conditions
Moderate to Severe Plaque-type Psoriasis
Interventions
Secukinumab (AIN457), Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
1,147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
37
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 28 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2018 · Synced Oct 25, 2026, 9:48 PM EDT