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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pre-diabetes Clear all
Withdrawn Not applicable Interventional

VA Diabetes Prevention: Epidemiology of Pre-Diabetes and Implementation Pilot

NCT01671735
View directory record Official record
Conditions
Diabetes
Interventions
Survey
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2012 · Synced Sep 25, 2026, 2:15 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Microlearning Application for Diabetes Prevention

NCT05071820
View directory record Official record
Conditions
PreDiabetes, Elevated Blood Sugar
Interventions
Health U mobile application, National Diabetes Prevention Program
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 25, 2026, 2:15 AM EDT
Not yet recruiting Not applicable Interventional

Diabetes Prevention by Group Intervention and CGM Use in Pre-diabetic Adults

NCT07543068
View directory record Official record
Conditions
Pre Diabetic, Hyperglycaemia (Non Diabetic)
Interventions
Combines group sessions and CGM-based behavioral feedback
Other
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Conroe, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 25, 2026, 2:15 AM EDT
Terminated Phase 4 Interventional Results available

Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Computed Tomography

NCT00209417
View directory record Official record
Conditions
Renal Insufficiency, Diabetes Mellitus
Interventions
Iodixanol 320-Arm 1, Iopamidol 300-Arm 2
Drug
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older
Enrollment
656 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 16, 2014 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-Centered Diabetes Project - Sharing Wisdom

NCT00438126
View directory record Official record
Conditions
Prediabetes, Metabolic Syndrome, Overweight, Obesity
Interventions
A lifestyle educational program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 40 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 1, 2010 · Synced Sep 25, 2026, 2:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Circadian Rhythms in Postmenopausal Women

NCT04893226
View directory record Official record
Conditions
Metabolic Syndrome, Postmenopausal Symptoms
Interventions
Time-Restricted Feeding (TRF)
Behavioral
Lead sponsor
Julie Pendergast
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Not applicable Interventional Results available

CTSI Pilot: Improving Adherence to Diabetic Diet

NCT04051008
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diet, Healthy, Pre-diabetes
Interventions
Online - use of online grocery shopping platform, Default - use of online grocery shopping platform with default shopping carts
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Not applicable Interventional

Pilot Study to Assess Pre-packaged, Portion-controlled Meal Plan on Weight Loss

NCT00593476
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
PCD, DSE
Other
Lead sponsor
Temple University
Other
Eligibility
21 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2013 · Synced Sep 25, 2026, 2:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics

NCT06116149
View directory record Official record
Conditions
Obesity, Gestational Diabetes, Lifestyle, Healthy, Glucose Intolerance During Pregnancy, PreDiabetes, Hyperglycemia
Interventions
In-person health coach delivery of the GLB, Technology-assisted health coach delivery of the GLB
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
18 Years and older · Female only
Enrollment
722 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Obesity and Intensity of Exercise on Ghrelin Levels

NCT04581980
View directory record Official record
Conditions
Obesity, Insulin Resistance, Cardiovascular Risk Factor
Interventions
Exercise
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 25, 2026, 2:15 AM EDT
Not listed Not applicable Interventional

Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting

NCT04564586
View directory record Official record
Conditions
PreDiabetes, Metabolic Syndrome, Protection Against
Interventions
DPPFit
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Sep 25, 2026, 2:15 AM EDT
Terminated Not applicable Interventional

Examining the Effects of Diet on Health in Prediabetes With an Online Program

NCT02188823
View directory record Official record
Conditions
Prediabetes
Interventions
Low carbohydrate diet
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Sep 25, 2026, 2:15 AM EDT
Recruiting Phase 4 Interventional

Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes

NCT05119179
View directory record Official record
Conditions
PreDiabetes
Interventions
Semaglutide
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Brownsville, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 25, 2026, 2:15 AM EDT
Active, not recruiting Not applicable Interventional

How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes

NCT07625046
View directory record Official record
Conditions
Pre Diabetic
Interventions
Fig, Control
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
30 Years to 50 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 25, 2026, 2:15 AM EDT
Terminated No phase listed Observational

Insulin Resistance Before and During Pregnancy in Women With Polycystic Ovary Syndrome

NCT01475565
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Insulin Resistance, Insulin Sensitivity, Obesity, Pregnancy
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 25, 2026, 2:15 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County

NCT06387797
View directory record Official record
Conditions
At Risk for Type 2 Diabetes Mellitus, Pre Diabetes
Interventions
Cooking Matters for Adults (CMA)
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 25, 2026, 2:15 AM EDT
Active, not recruiting Not applicable Interventional

Mechanisms of Prediabetic States in Sleep Apnea

NCT04234217
View directory record Official record
Conditions
Sleep Apnea, Pre-diabetes
Interventions
Continuous positive airway pressure, Niacin
Device · Other
Lead sponsor
University of Chicago
Other
Eligibility
20 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 25, 2026, 2:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

NCT06112418
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Interventions
The Cleerly CAD Staging System
Device
Lead sponsor
Cleerly, Inc.
Industry
Eligibility
55 Years and older
Enrollment
7,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
125
States / cities
Chandler, Arizona • Scottsdale, Arizona • Sun City, Arizona + 100 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 25, 2026, 2:15 AM EDT
Recruiting Early Phase 1 Interventional

Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes

NCT05041491
View directory record Official record
Conditions
Pre-diabetes
Interventions
BREAK, ONE
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Not applicable Interventional Results available

Coordinating Pragmatic Primary Care Population Management for Obesity

NCT03998046
View directory record Official record
Conditions
Obesity, Cardiovascular Risk Factor
Interventions
Outreach Support for Weight Loss Goal Setting and Self-Weighing, Outreach Decision Support to Encourage Linkages to Intensive Community Lifestyle Interventions, Adaptive Tailoring of Information Delivery and Intensity of Primary Care Outreach Support
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Not applicable Interventional

A Pilot Study of a Lifestyle Intervention on the Metabolic Syndrome (3ELM Study)

NCT02233088
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
ELM Group, ELM Classes, ELM Individual
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 72 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Not applicable Interventional

The Avoiding Diabetes Thru Action Plan Targeting Pilot Randomized Control Trial

NCT01473654
View directory record Official record
Conditions
Prediabetes
Interventions
ADAPT tool
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2014 · Synced Sep 25, 2026, 2:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Trial of Early Initiation of CGM-Guided Insulin Therapy in Stage 2 T1D

NCT04335513
View directory record Official record
Conditions
Type 1 Diabetes, Prediabetic State, Dysglycemia, Autoimmune Diabetes
Interventions
Early CGM-guided education and initiation of insulin therapy., Usual care: glucometer surveillance and basic education.
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
2 Years to 20 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 25, 2026, 2:15 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Metformin to Augment Low Milk Supply (MALMS) Study

NCT02179788
View directory record Official record
Conditions
Low Milk Supply, Pre-diabetes, Insulin Resistance, Suppressed Lactation
Interventions
Standard care, Metformin, Placebo
Behavioral · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
20 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 25, 2026, 2:15 AM EDT