Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 21, 2026, 3:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 178 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Pre-exposure Prophylaxis (PrEP) Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetics and Pharmacodynamics of DMPA With HIV PrEP

NCT03197961
View directory record Official record
Conditions
HIV/AIDS, Contraception
Interventions
tenofovir/emtricitabine, DMPA
Combination Product · Drug
Lead sponsor
Sharon Achilles
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing HIV PrEP Through Shared Decision Making

NCT03019770
View directory record Official record
Conditions
Pre-Exposure Prophylaxis
Interventions
PrEP Decision Aid
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Study Evaluating Implementation Strategies for the Delivery of Cabotegravir in Low and High-Volume PrEP Site in the United States

NCT05374525
View directory record Official record
Conditions
HIV Infections
Interventions
APRETUDE, Cabotegravir OLI
Drug
Lead sponsor
ViiV Healthcare
Industry
Eligibility
18 Years and older · Male only
Enrollment
287 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
17
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 14 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 21, 2026, 3:57 PM EDT
Recruiting Phase 4 Interventional

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

NCT05669534
View directory record Official record
Conditions
Hiv, Opioid Use Disorder
Interventions
community-friendly health recovery program, Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis
Behavioral · Drug
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 21, 2026, 3:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Factors Affecting PrEP Adherence

NCT02411630
View directory record Official record
Conditions
HIV Infection
Interventions
Emtricitabine/tenofovir disoproxil
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 22 Years · Male only
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
12
States / cities
Los Angeles, California • Aurora, Colorado • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Trial of iTAB Plus Motivational Interviewing for PrEP Adherence in Transgender Individuals

NCT03086200
View directory record Official record
Conditions
Patient Adherence, HIV Seronegativity
Interventions
brief Motivational Interviewing
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
263 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
5
States / cities
Los Angeles, California • San Diego, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2021 · Synced Sep 21, 2026, 3:57 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

PrEP4U: Assessing the Effectiveness of Integrated Same-Day Lenacapavir Initiation and Follow-up Choice on PrEP Persistence

NCT07335289
View directory record Official record
Conditions
HIV Pre-exposure Prophylaxis Use
Interventions
Choice of follow up, Follow up via standard clinic
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW

NCT04760691
View directory record Official record
Conditions
HIV, Prophylaxis, Transgender
Interventions
Truvada alone, Truvada plus Leuprolide 11.25mg intramuscular injection, Truvada plus Estradiol 1 mg, Truvada plus Estradiol 6 mg, Estradiol 6 mg alone
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males

NCT04692077
View directory record Official record
Conditions
HIV Infections
Interventions
Cabotegravir (CAB) tablet, CAB LA, Tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) tablet
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Up to 17 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
4
States / cities
Aurora, Colorado • Chicago, Illinois • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Men's Prevention Apps to Research Efficacy

NCT03965221
View directory record Official record
Conditions
HIV/AIDS, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
Interventions
LYNX, MyChoices
Behavioral
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
381 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
8
States / cities
Tampa, Florida • Atlanta, Georgia • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study

NCT03652623
View directory record Official record
Conditions
HIV/AIDS, Gender, Behavior and Behavior Mechanisms
Interventions
TDF/FTC
Drug
Lead sponsor
Hektoen Institute for Medical Research
Other
Eligibility
15 Years to 24 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 31, 2024 · Synced Sep 21, 2026, 3:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Longer-Acting PrEP in Transgender and Gender Diverse Texans

NCT05044286
View directory record Official record
Conditions
HIV-1-infection
Interventions
no intervention
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 100 Years
Enrollment
565 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Sep 21, 2026, 3:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Predictors of Health Service Utilizations Among Key Population in Washington DC

NCT06046079
View directory record Official record
Conditions
Pre-exposure Prophylaxis, HIV, Health Behavior
Interventions
Not listed
Lead sponsor
Us Helping Us, People Into Living, Inc.
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adapting a Behavioral Intervention to Accommodate Cognitive Dysfunction in People Who Inject Drugs

NCT05912374
View directory record Official record
Conditions
Cognitive Dysfunction
Interventions
standard Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB), enhanced Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB)
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PrEP iT! Mobile App Intervention

NCT04509076
View directory record Official record
Conditions
Treatment Adherence and Compliance
Interventions
PrEP iT! (plus usual PrEP care), Usual PrEP care
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing PrEP Uptake & Adherence Among Male Sex Workers (MSW) Using a 2-stage Randomization Design

NCT03086057
View directory record Official record
Conditions
Prevention
Interventions
PrEPare for Work: Strength Based Case Management (Stage 1), PrEPare for Work: Adherence Training and Counseling (Stage 2)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 14, 2021 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

NCT02720094
View directory record Official record
Conditions
HIV Infections
Interventions
Cabotegravir Oral Tablet, TDF/FTC tablets, Placebo for TDF/FTC tablets, Placebo for cabotegravir oral tablet, CAB LA, Placebo for CAB LA
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
4,570 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
27
States / cities
Birmingham, Alabama • Los Angeles, California • Oakland, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional

Pilot Mobile Medical Unit Study for I'm Fully Empowered4Her

NCT05644834
View directory record Official record
Conditions
HIV Prevention, Pre-exposure Prophylaxis, PrEP, Prevention, Women's Health, Mobile Health
Interventions
I'm Fully Empowered for Her (IFE4Her)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Linkage of Transgender Individuals to PrEP

NCT03191474
View directory record Official record
Conditions
HIV Seronegativity, Linkage
Interventions
T-POWr Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2021 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile-Based Application "MyChoices"

NCT03179319
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
Interventions
MyChoices
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Sep 21, 2026, 3:57 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

HIV Pre-Exposure Prophylaxis Among an Unrecognized Sexual Minority Population

NCT05815030
View directory record Official record
Conditions
Pre-Exposure Prophylaxis
Interventions
video informational/educational intervention
Other
Lead sponsor
The Alternative Sexualities Health Research Alliance
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rio Vista, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 21, 2026, 3:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

PEP/PrEP Via Pharmacist-Prescribing Implementation (PEPPI)

NCT07683117
View directory record Official record
Conditions
HIV Prevention, HIV Pre-exposure Prophylaxis, Access and Linkage to Healthcare, Technology Use
Interventions
PEPPI Pharmacies
Other
Lead sponsor
EMPOWERX INC
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 21, 2026, 3:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Finding the Right Tenofovir/Emtricitabine Regimen for Pre-Exposure Prophylaxis (PrEP) in Transgender Women

NCT03060785
View directory record Official record
Conditions
HIV Prevention
Interventions
Tenofovir Disoproxil Fumarate/Emtricitabine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Sep 21, 2026, 3:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PrEP With TDF/FTC to Prevent HIV-1 Acquisition in Young MSM and Transgender Women of Color

NCT02367807
View directory record Official record
Conditions
HIV
Interventions
Emtricitabine and tenofovir disoproxil fumarate
Drug
Lead sponsor
Philadelphia Fight
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2016 · Synced Sep 21, 2026, 3:57 PM EDT