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Showing 289–312 of 811 matching trials from the live ClinicalTrials.gov search.
Conditions
Premature Birth, Antibiotics, Neurodevelopment
Interventions
Ampicillin, Gentamicin, Placebo
Drug
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 30 Weeks
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
14
States / cities
San Diego, California • New Haven, Connecticut • Tampa, Florida + 9 more
Completed Not applicable Interventional Accepts healthy volunteers

Tobacco Use in Pregnancy Intervention for Cessation

NCT03442530
Conditions
Pregnancy
Interventions
ToPIC, Tobacco Treatment As Usual (TTAU)
Behavioral
Lead sponsor
Kristin Ashford
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Obstetric Labour, Premature
Interventions
Retosiban IV infusion, Placebo IV infusion
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years to 45 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
33
States / cities
Birmingham, Alabama • Mobile, Alabama • Tucson, Arizona + 29 more
Completed No phase listed Observational

The Biomarker Study

NCT01148654
Conditions
Preterm Birth, Preterm Labor
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
Female only
Enrollment
1,076 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Premature Infants
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 7 Days
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Premature Birth
Interventions
Written information and verbal counseling
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Premature Birth
Interventions
Language Treatment, Control Treatment
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
24 Weeks to 31 Weeks
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Labor Pain
Interventions
No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
Other · Drug
Lead sponsor
Neil Roy Connelly, MD
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Springfield, Massachusetts
Conditions
Malnutrition
Interventions
Parenteral Nutrition
Drug
Lead sponsor
Pediatrix
Other
Eligibility
0 Years to 48 Hours
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Florence, South Carolina
Completed No phase listed Observational Accepts healthy volunteers

Pulse Oximetry Performance Comparison in Newborns

NCT06637917
Conditions
Newborn, Birth, Preterm
Interventions
OxySoftN™ Neonatal-Adult SpO2 Sensor with N600X Nellcor™ Patient Monitoring System, LNCS® NEO SpO2 Sensor with RAD-97™ Pulse CO-Oximeter, 1041PTS (or similar) Kendall™ Neonatal Electrodes with IntelliVue MP5 Portable Patient Monitor
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
29 Weeks and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Los Angeles, California • St Louis, Missouri • Winston-Salem, North Carolina
Completed Phase 3 Interventional Accepts healthy volunteers Results available

PREGNANT Short Cervix Trial

NCT00615550
Conditions
Preterm Delivery, Short Cervix, Short Uterine Cervical Length
Interventions
progesterone, placebo
Drug
Lead sponsor
Juniper Pharmaceuticals, Inc.
Industry
Eligibility
15 Years to 45 Years · Female only
Enrollment
465 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
27
States / cities
Mobile, Alabama • Phoenix, Arizona • Orange, California + 21 more
Conditions
Child Development, Premature Birth
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
4 Months to 50 Years
Enrollment
90 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Relationship Between Plasma Concentration of Hydroxyprogesterone Caproate (17-OHPC) and Preterm Birth

NCT03292731
Conditions
Preterm Birth
Interventions
17-Hydroxyprogesterone caproate 250mg or 500 mg., Safety study of 500 mg dose.
Drug
Lead sponsor
Steve N. Caritis, MD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
5
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania • Galveston, Texas + 2 more
Conditions
Neonates or Premature Babies, Parent, Reading, NICU Infants
Interventions
Shared reading program
Other
Lead sponsor
Catherine Caruso
Other
Eligibility
Not listed
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Recruiting Not applicable Interventional Accepts healthy volunteers

I-InTERACT Preterm Parenting

NCT06767293
Conditions
Child Behavior Problem, Preterm, Parent-Child Relations, Parenting
Interventions
I-InTERACT Parenting Intervention (I2P) and coaching sessions, I-InTERACT Parenting Microlearning Intervention (I2P Micro) and coaching sessions, Internet Resources
Behavioral · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 8 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Active, not recruiting Phase 2 Interventional

RIC-NEC Randomized Controlled Trial

NCT05279664
Conditions
Necrotizing Enterocolitis
Interventions
Remote ischemic conditioning (RIC) + Standard of Care for NEC, Standard of Care for NEC
Other
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
0 Weeks and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed No phase listed Observational Accepts healthy volunteers

Alteration of Stool Microbiota in Preterm Infants With Anemia

NCT03554278
Conditions
Anemia, Neonatal, Necrotizing Enterocolitis, Dysbiosis
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
7 Days to 30 Days
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Recruiting Phase 2 Interventional Accepts healthy volunteers

The Effect of Sulfasalazine on CRH Levels in Pregnant Women

NCT05703425
Conditions
Preterm Birth
Interventions
Sulfasalazine
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
Cardiovascular Diseases, Diabetes, Gestational Diabetes, Preeclampsia, Gestational Hypertension, Small for Gestational Age at Delivery, Preterm Birth, Overweight and Obesity
Interventions
Fit After Baby, Text4Baby Control Group
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Premature Birth
Interventions
smallTalk NICU Active
Device
Lead sponsor
Thrive Neuromedical, LLC
Industry
Eligibility
32 Weeks to 35 Weeks
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia • Chagrin Falls, Ohio
Conditions
Preterm Birth
Interventions
Hydroxyprogesterone Caproate Injection (HPC), 250mg/mL, Vehicle
Drug
Lead sponsor
AMAG Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,740 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
41
States / cities
Montgomery, Alabama • Tucson, Arizona • La Mesa, California + 35 more
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial

NCT00033917
Conditions
Intraventricular Hemorrhage (IVH), Bleeding in the Brain, Prematurity, Very Low Birth Weight Infants
Interventions
indomethacin, placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
Up to 6 Hours
Enrollment
630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1989 – 2012
U.S. locations
3
States / cities
New Haven, Connecticut • Portland, Maine • Providence, Rhode Island
Conditions
Premature Birth
Interventions
Dino Egg
Device
Lead sponsor
Jonathan Slaughter
Other
Eligibility
32 Weeks to 34 Weeks
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Improving Preterm Outcomes by Safeguarding Maternal Mental Health

NCT01892982
Conditions
Depression, Child Development
Interventions
Problem Solving Education tailored to NICU
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Up to 64 Years
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
4
States / cities
Boston, Massachusetts