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ClinicalTrials.gov public records Last synced Sep 8, 2026, 10:51 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prediabetic Clear all
Completed Not applicable Interventional

Physical Activity and Obesity

NCT02060240
View directory record Official record
Conditions
Obesity, Prediabetic State, Sedentary Lifestyle
Interventions
High Activity
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
30 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Sep 8, 2026, 10:51 PM EDT
Recruiting No phase listed Observational

This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder

NCT07804680
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome, Prediabetes
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
6 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RCT of a Polyherbal Dietary Supplement for Prediabetes

NCT03388762
View directory record Official record
Conditions
Prediabetic State
Interventions
GlucoSupreme™ Herbal, Placebo
Dietary Supplement · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
4
States / cities
Baltimore, Maryland • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Results available

Diabetes Prevention Program Feasibility Study of Breastfeeding

NCT04021602
View directory record Official record
Conditions
Pregnancy, Overweight and Obesity
Interventions
Diabetes Prevention Program, Breastfeeding Education, Usual Care
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Lakin, Kansas • Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial

NCT03640286
View directory record Official record
Conditions
Obesity
Interventions
VeSTAL
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
La Jolla, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional

MEAL TIMING Study: Effect of Time-Restricted Feeding on 24-hour Glycemic Control, Blood Pressure, and Cardiovascular Disease Risk Factors in Adults With Prediabetes

NCT03504683
View directory record Official record
Conditions
PreDiabetes
Interventions
Early TRE, Mid-day TRE, Control Schedule
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years to 70 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Active, not recruiting Not applicable Interventional

Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology

NCT05523375
View directory record Official record
Conditions
Obesity, Diabetes Mellitus, Type 2, PreDiabetes
Interventions
Intensive Lifestyle Intervention
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
40 Years to 70 Years
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 8, 2026, 10:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Eating Almonds Before a Meal to Control Blood Sugar

NCT07603739
View directory record Official record
Conditions
Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Precision Medicine, Nutrition
Interventions
Premeal almond ingestion
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
25 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional

Chromium Picolinate for the Treatment of Metabolic Syndrome

NCT00128154
View directory record Official record
Conditions
Metabolic Syndrome X, Prediabetic State, Insulin Resistance, Obesity, Metabolic Diseases
Interventions
Chromium picolinate
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Sep 8, 2026, 10:51 PM EDT
Recruiting Not applicable Interventional

Rural Alliance for Diabetes Prevention

NCT06252038
View directory record Official record
Conditions
PreDiabetes
Interventions
Zoom Group Video (GV), Self Directed (SD)
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Recruiting Not applicable Interventional

CGM-Enhanced DPP to Prevent Type 2 Diabetes in Adults With Prediabetes

NCT07140848
View directory record Official record
Conditions
PreDiabetes
Interventions
CGM-DPP, Control
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Results available

Augmented Care at Worksite for Diabetes Prevention

NCT03382873
View directory record Official record
Conditions
PreDiabetes
Interventions
Group Lifestyle Balance (GLB), Group Lifestyle Balance Plus (GLB+)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
21 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

WorkWell: Work-based Activity and Metabolic Health

NCT04269070
View directory record Official record
Conditions
PreDiabetes, Obesity
Interventions
Standing condition, Light physical activity (LPA) condition, Usual behavior condition
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Phase 1 Interventional

Evaluation of Empagliflozin vs Standard Care in Veterans With Prediabetes

NCT06828731
View directory record Official record
Conditions
Prediabetes
Interventions
Empagliflozin 10mg daily, Lifestyle education
Drug · Other
Lead sponsor
Charles George VA Medical Center
Federal
Eligibility
35 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Asheville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Phase 4 Interventional Results available

Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults

NCT05786521
View directory record Official record
Conditions
Aging, Diabetes Mellitus, Type 2, PreDiabetes, Overweight and Obesity
Interventions
Semaglutide Injectable Product, Lifestyle Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
65 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 8, 2026, 10:51 PM EDT
Not yet recruiting Phase 3 Interventional

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

NCT07794579
View directory record Official record
Conditions
Overweight, Prediabetic State, Prehypertension, Obesity, Abdominal
Interventions
Orforglipron, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
2,001 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
79
States / cities
Anniston, Alabama • Birmingham, Alabama • Pelham, Alabama + 73 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low-Carbohydrate Dietary Pattern on Glycemic Outcomes Trial

NCT03675360
View directory record Official record
Conditions
Diabetes, PreDiabetes, Metabolic Disease, Hyperglycemia, Diet Modification, Glucose Intolerance, Glucose Metabolism Disorders (Including Diabetes Mellitus), Endocrine System Diseases
Interventions
Low-Carbohydrate Diet
Behavioral
Lead sponsor
Tulane University School of Public Health and Tropical Medicine
Other
Eligibility
40 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 8, 2026, 10:51 PM EDT
Withdrawn Phase 4 Interventional

Metformin Versus Standard of Care Treatment in Pregnant Women With Prediabetes

NCT04523363
View directory record Official record
Conditions
Prediabetes; Complicating Pregnancy
Interventions
Metformin
Drug
Lead sponsor
Gianna Wilkie
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Results available

Continuous Glucose Monitoring in Diabetes and Prediabetes

NCT03805412
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Obesity
Interventions
DEXCOM G6 RT-CGM
Device
Lead sponsor
Nicole Ehrhardt, MD
Other
Eligibility
18 Years to 55 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Whole Prediabetes: A Family-Centered Whole Foods Diet in Adults With Prediabetes and Their Offspring

NCT05483972
View directory record Official record
Conditions
PreDiabetes
Interventions
Whole Prediabetes Diet Intervention
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
25 Years to 59 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Sep 8, 2026, 10:51 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Study of a Diabetes Prevention Patient Activation Clinical Decision Support Tool

NCT06358261
View directory record Official record
Conditions
PreDiabetes, Lifestyle, Healthy, Activation, Patient
Interventions
Diabetes Prevention Patient Activation Clinical Decision Support Tool
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
25 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Enrolling by invitation Not applicable Interventional

Food Sequencing in Food Insecurity

NCT07488767
View directory record Official record
Conditions
Prediabetes, Diabetes Mellitus, Food Insecurity
Interventions
Food Order/Meal Sequencing, Standard of Care Counseling
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 8, 2026, 10:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fuel Utilization, Diet Composition, and Exercise in African American Women

NCT04293367
View directory record Official record
Conditions
Obesity, Diabetes, Insulin Resistance
Interventions
High Intensity Interval Training (HIIT)
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Sep 8, 2026, 10:51 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Blood Markers of Early Pancreas Cancer

NCT03568630
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited Disease
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
1,250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 8, 2026, 10:51 PM EDT