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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prefrontal Cortex Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Brain Stimulation (tDCS) in Food Cravings Control in Overweight/Obese Women

NCT04420767
View directory record Official record
Conditions
Obesity
Interventions
tDCS, Sham brain stimulation, Go-No GO task
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational

PET Scan to Map the Areas of the Brain Involved in Planning

NCT00001363
View directory record Official record
Conditions
Cognition Disorders
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational

Effect of Functional Genetic Polymorphisms on Brain Morphology and Function

NCT01035723
View directory record Official record
Conditions
Drug Abuse
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Processing of Language Meanings

NCT00005004
View directory record Official record
Conditions
Central Nervous System Disease, Cerebrovascular Accident, Craniocerebral Trauma, Head Injury, Healthy, Stroke
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Glutamate Probes in Adolescent Depression

NCT02307617
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Disorder, Recurrent, Major Depressive Disorder, Remitted
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Jul 24, 2026, 2:49 AM EDT
Terminated Not applicable Interventional

Transcranial Direct Current Stimulation (tDCS) in Chronic Post-Stroke Apathy

NCT02915484
View directory record Official record
Conditions
Apathy, Stroke
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational

Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in People With Functional Movement Disorders

NCT03263013
View directory record Official record
Conditions
Movement Disorders
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Jul 24, 2026, 2:49 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dorsolateral Prefrontal Cortex Transcranial Direct Current and Muscle Fatigue Stimulation on Muscle Fatigue

NCT06389162
View directory record Official record
Conditions
Fatigue
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Jul 24, 2026, 2:49 AM EDT
Completed Early Phase 1 Interventional Results available

Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent

NCT03681769
View directory record Official record
Conditions
Chronic Pain, Opiate Dependence, Lower Back Pain
Interventions
iTBS to the left dlPFC, Sham iTBS to the left dlPFC, cTBS to the mPFC, Sham cTBS to the mPFC
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jul 24, 2026, 2:49 AM EDT
Withdrawn Not applicable Interventional

Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD

NCT04543513
View directory record Official record
Conditions
PTSD, Cognitive Function
Interventions
Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
Other
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Jul 24, 2026, 2:49 AM EDT
Recruiting Not applicable Interventional

PCS in Severe Treatment Resistant Depression

NCT04124341
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Prefrontal Cortical Stimulation (PCS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Jul 24, 2026, 2:49 AM EDT
Completed Phase 4 Interventional

Comparison of Anodal Transcranial Direct Current Stimulation (t-DCS) and Sham Stimulation in Patients With Treatment-resistant Depression

NCT02141776
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Transcranial direct current stimulation (t-DCS), Sham Controlled Arm
Device · Other
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Jul 24, 2026, 2:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

NCT02674516
View directory record Official record
Conditions
Antisocial Behavior, Aggression
Interventions
Transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Jul 24, 2026, 2:49 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

High-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in PTSD

NCT02873299
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
10 Hz rTMS of the right dorsolateral prefrontal cortex, 20 Hz rTMS of the right dorsolateral prefrontal cortex
Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Brain Function During Cognitive Tasks

NCT00076739
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years to 40 Years
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Encoding for Memory

NCT00051870
View directory record Official record
Conditions
Healthy
Interventions
Magstim Rapid Magnetic Stimulator
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 24, 2026, 2:49 AM EDT
Completed Not applicable Interventional Results available

Effect of Theta Burst Stimulation on Alcohol Cue Reactivity

NCT04223154
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence, Alcohol Abuse
Interventions
Real iTBS to the dlPFC, Sham iTBS to the dlPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jul 24, 2026, 2:49 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype

NCT00548327
View directory record Official record
Conditions
Schizophrenia, Memory Disorders, Cognition Disorders
Interventions
Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing, Placebo
Drug · Procedure
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 45 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 13, 2013 · Synced Jul 24, 2026, 2:49 AM EDT
Completed Phase 2 Interventional

Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

NCT00029666
View directory record Official record
Conditions
Parkinson Disease
Interventions
Neopulse Magnetic Stimulator
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 24, 2026, 2:49 AM EDT
Active, not recruiting Phase 3 Interventional

Treating Schizophrenia by Correcting Abnormal Brain Development

NCT00179465
View directory record Official record
Conditions
Schizophrenia
Interventions
Tiagabine, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 25 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Jul 24, 2026, 2:49 AM EDT
Completed Phase 2 Interventional

10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence

NCT03238859
View directory record Official record
Conditions
Cocaine Dependence, Alcohol Dependence
Interventions
Real cTBS, Sham cTBS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Jul 24, 2026, 2:49 AM EDT
Recruiting Not applicable Interventional

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

NCT04998916
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking, Substance Use, Drinking, Alcohol, Alcohol Use Disorder (AUD)
Interventions
Real TBS to the mPFC, Sham TBS to the mPFC
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jul 24, 2026, 2:49 AM EDT
Completed No phase listed Observational

Effect of Gabapentin on GABA Concentration and Emotional Processing

NCT00094510
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 24, 2026, 2:49 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Medial-prefrontal Enhancement During Schizophrenia Systems Imaging

NCT04807530
View directory record Official record
Conditions
Schizophrenia
Interventions
TMS
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 64 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Jul 24, 2026, 2:49 AM EDT