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ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:28 AM EDT

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Showing 1–24 of 69 matching trials from the live ClinicalTrials.gov search.
Conditions
Maternal Neoplasia
Interventions
NIPT
Device
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 100 Years · Female only
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Completed No phase listed Observational Accepts healthy volunteers

High Risk Multiple Gestation Study

NCT02278874
Conditions
Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
Interventions
Not listed
Lead sponsor
Natera, Inc.
Industry
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
Boston, Massachusetts • Glen Cove, New York • New York, New York + 1 more
Conditions
Pregnancy Following IVF With PGS/PGD
Interventions
Blood draw
Procedure
Lead sponsor
Natera, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Redwood City, California
Conditions
Genetic Disease, Genetic Syndrome, Prenatal Disorder, Prenatal Maternal Abnormality, Pregnancy Complications
Interventions
NEST, Usual care
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
691 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Cleveland, Ohio
Conditions
Copy Number Variations
Interventions
MaterniT GENOME
Device
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years to 89 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Not listed Not applicable Interventional Accepts healthy volunteers

Cell-Based Noninvasive Prenatal Testing

NCT05245266
Conditions
Pregnancy Related
Interventions
Redraw for analysis of blood samples from healthy pregnant women
Diagnostic Test
Lead sponsor
Luna Genetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Conditions
Down Syndrome, Edwards Syndrome, Patau Syndrome, Turner Syndrome
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study

NCT07557303
Conditions
Delivery of Health Care, Genetic Testing, Humans, Pregnancy, Noninvasive Prenatal Testing, Informed Consent, Internet-Based Intervention, Self Efficacy, Pregnant People, Decision Making, Health Education, Patient Education as Topic/Method
Interventions
Mobile-based Educational Intervention
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
3
States / cities
San Francisco, California • Jacksonville, Florida • Chapel Hill, North Carolina
Conditions
Pregnancy - Prenatal Testing
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 55 Years · Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Maternal and Child Health Through Point-of-care STI Testing

NCT07290439
Conditions
Treponema Pallidum Infection, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginalis Vaginitis, Sexually Transmitted Infection
Interventions
Point-of-care STI tests, Standard of care STI testing
Diagnostic Test
Lead sponsor
Emory University
Other
Eligibility
Female only
Enrollment
756 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Trisomy 21, Trisomy 18, Trisomy 13, Sex Chromosome Abnormalities, Microdeletion Syndromes
Interventions
Not listed
Lead sponsor
Natera, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,059 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
7
States / cities
San Carlos, California • San Gabriel, California • Washington D.C., District of Columbia + 4 more
Conditions
Hereditary Cancer Syndrome
Interventions
Natera empower comprehensive hereditary cancer panel, Obstetrical carrier screening
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Stillbirth, Grief, Infant Death
Interventions
BabyCenter site and the community group
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Obesity Complicating Childbirth
Interventions
Ultrasound Examination, Antenatal Testing (biophysical profile)
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational

Shifting Options Study

NCT07225595
Conditions
Prenatal Care, Prenatal Diagnosis
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
78 participants
Timeline
2025 – 2026
U.S. locations
2
States / cities
Cleveland, Ohio
Conditions
Fetal Sex Determination
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years to 64 Years · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
San Diego, California
Conditions
Pregnancy
Interventions
Video education
Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Diego, California
Completed No phase listed Observational Accepts healthy volunteers

Multiple Gestation Study

NCT02278536
Conditions
Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
Interventions
Not listed
Lead sponsor
Natera, Inc.
Industry
Eligibility
18 Years and older
Enrollment
354 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
6
States / cities
San Carlos, California • San Diego, California • New York, New York + 2 more
Conditions
Pregnant Women, Prenatal Care
Interventions
Not listed
Lead sponsor
Verinata Health, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Fort Collins, Colorado + 8 more
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Decision Assisting Tool for Prenatal Testing

NCT00686062
Conditions
Pregnancy
Interventions
Control - computerized age-appropriate prenatal testing educational brochure, PT Tool - interactive, computerized, prenatal testing decision tool
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
494 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2004
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Results available

Maternal Fetal Device Performance Twins

NCT06835647
Conditions
Pregnancy
Interventions
Investigational Fetal Monitor, Ultrasound Imaging Device
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Louisville, Colorado
Conditions
Chlamydia Trachomatis Infection, Neonatal Infection, Preterm Birth, Gonorrhea
Interventions
Chlamydia trachomatis and Neisseria gonorrhoeae screening using the GeneXpert
Other
Lead sponsor
University of Southern California
Other
Eligibility
15 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Attitudes and Decision-making After Pregnancy Testing Study

NCT03888404
Conditions
Unintended Pregnancy, Undesired Pregnancy
Interventions
Pregnancy preferences (Aim 1), Sociocultural environment (Aim 2), Pregnancy preferences (Aim 3a), Pregnancy (Aim 3b)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 34 Years · Female only
Enrollment
2,015 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Oakland, California
Terminated No phase listed Observational Accepts healthy volunteers

Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial

NCT01545674
Conditions
Trisomy 13, Trisomy 18, Trisomy 21, Aneuploidy
Interventions
Blood Draw
Procedure
Lead sponsor
Natera, Inc.
Industry
Eligibility
Female only
Enrollment
937 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
24
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 16 more