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Showing 1–24 of 268 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pregnancy Induced Hypertension Clear all
Completed Phase 1Phase 2 Interventional

Antenatal Platelet Response on Aspirin: a Pharmacokinetic Study Through Pregnancy

NCT04645004
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin 81Mg Non-enteric coated Tab
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
13 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Jul 21, 2026, 5:04 AM EDT
Not yet recruiting No phase listed Observational

Gestational Changes in Hemodynamics and Respiratory Mechanics in Association With Pre-Eclampsia

NCT07695909
View directory record Official record
Conditions
Pre-eclampsia, Pregnancy, Post Partum
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Active, not recruiting Not applicable Interventional

Mindfulness & Mechanisms Study

NCT04626245
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Mindfulness training
Behavioral
Lead sponsor
Lifespan
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Terminated Phase 2 Interventional Results available

Mechanisms of EPO-induced Hypertension

NCT03810911
View directory record Official record
Conditions
Chronic Kidney Disease, Blood Pressure, Anemia
Interventions
Darbepoetin
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Platelet Count Trends in Pre-eclamptic Parturients

NCT00787241
View directory record Official record
Conditions
Obstetric Labor Complications, Preeclampsia, Thrombocytopenia
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
445 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2003
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational

First Trimester Prediction of Preeclampsia and Fetal Growth Restriction

NCT02379494
View directory record Official record
Conditions
Preeclampsia, Fetal Growth Restriction
Interventions
Not listed
Lead sponsor
Fetal Medicine Foundation
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Jul 21, 2026, 5:04 AM EDT
Not yet recruiting Phase 4 Interventional

Biomarkers in Management of Post Partum Preeclampsia

NCT07478055
View directory record Official record
Conditions
Preeclampsia Severe, Preeclampsia Postpartum
Interventions
Magnesium Sulfate
Drug
Lead sponsor
Alexander Harrison
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational

User Testing and Feedback for a Mobile Health Program for Postpartum Women: A Pilot Study

NCT02384226
View directory record Official record
Conditions
Gestational Diabetes Mellitus, Preeclampsia, Gestational Hypertension, Pre-term Delivery, Delivery of Small for Gestational Age (SGA) Baby
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Advancing Understanding of Transportation Options

NCT04141891
View directory record Official record
Conditions
Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa, Vision Disorders, Acute Coronary Syndrome, Implantable Defibrillator User, Congestive Heart Failure, Hypertrophic Obstructive Cardiomyopathy, Orthostatic Hypotension, Syncope, Presyncope, Narcolepsy, Dementia, Multiple Sclerosis, Parkinson Disease, Brain Injuries, Spinal Cord Injuries, Stroke, Vertigo, Dizziness, Seizures, Substance Use, Insulin Dependent Diabetes Mellitus, Arthritis, Foot--Abnormalities, Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, End Stage Renal Disease, Sleep Apnea, Insomnia, Restless Legs Syndrome
Interventions
Driving Decision Aid, Older Drivers Website
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
3
States / cities
La Jolla, California • Aurora, Colorado • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Novel Biomarkers of Preeclampsia, Aquaporin, Fatty Acid, and S110B

NCT03567551
View directory record Official record
Conditions
Preeclampsia
Interventions
Women w/ Preeclampsia w/o Visual Disturbances or Headache, Women w/ Preeclampsia w/ Visual Disturbances or Headaches, Women w/o Preeclampsia
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
20 Years to 65 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Jul 21, 2026, 5:04 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Treatment of Severe Hypertension With ICG Directed Therapy

NCT04748107
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Impendence Cardiography
Diagnostic Test
Lead sponsor
Marshall University
Other
Eligibility
15 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Active, not recruiting No phase listed Observational

MIRACLE of LIFE Study

NCT06074601
View directory record Official record
Conditions
Preterm Labor, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane, Preeclampsia, HELLP, Gestational Hypertension, Gestational Diabetes Mellitus in Pregnancy, Small for Gestational Age at Delivery, Intrauterine Growth Restriction
Interventions
Mirvie Predictive Test for Adverse Pregnancy Outcomes
Diagnostic Test
Lead sponsor
Mirvie
Industry
Eligibility
18 Years and older · Female only
Enrollment
10,000 participants
Timeline
2021 – 2025
U.S. locations
10
States / cities
San Diego, California • Orlando, Florida • New Orleans, Louisiana + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Jul 21, 2026, 5:04 AM EDT
Terminated Not applicable Interventional Results available

Oral Progesterone and Low Dose Aspirin in the Prevention of Preeclampsia

NCT00719537
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin, Placebo Oral Tablet, Progesterone
Drug
Lead sponsor
John Uckele
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional

STAMPP-HTN in a High-risk Rural Population of Women

NCT04570124
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Home Blood Pressure Telemonitoring
Device
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Jul 21, 2026, 5:04 AM EDT
Not yet recruiting Not applicable Interventional

Mobile Health Program for Post-Preeclampsia Hypertension

NCT07599579
View directory record Official record
Conditions
Hypertension (HTN), Preeclampsia, Hypertensive Disorders of Pregnancy (HDP)
Interventions
Coaching application, Home-based blood pressure monitoring, WebMD
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Recruiting Phase 4 Interventional

AtorvaStatin Postpartum and Reduction of Cardiovascular risK

NCT06632379
View directory record Official record
Conditions
Hypertensive Disorders of Pregnancy, Preeclampsia, Gestational Hypertension
Interventions
Atorvastatin 10 mg, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features

NCT02911701
View directory record Official record
Conditions
Pre-Eclampsia, HELLP Syndrome, Eclampsia
Interventions
Acetaminophen, Ibuprofen
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Suspended Phase 1 Interventional

Evaluation of the Safety of Relaxin in Preeclampsia

NCT00333307
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
recombinant human relaxin
Drug
Lead sponsor
Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
2
States / cities
Lexington, Kentucky • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 15, 2010 · Synced Jul 21, 2026, 5:04 AM EDT
Recruiting Phase 1Phase 2 Interventional

Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

NCT06826859
View directory record Official record
Conditions
Preterm Birth, Preeclampsia
Interventions
Daily aspirin (ASA), Split dose aspirin (ASA)
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
16 Years to 55 Years · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Phase 4 Interventional Results available

Pharmacokinetics of Amlodipine Besylate at Delivery and During Lactation

NCT02353806
View directory record Official record
Conditions
Chronic Hypertension in Pregnancy
Interventions
Amlodipine besylate
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Jul 21, 2026, 5:04 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project

NCT05989581
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Labetalol or Nifedipine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 89 Years · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prognostic Indicators as Provided by the EPIC ClearView

NCT01476995
View directory record Official record
Conditions
Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation, Hypertension, Pyelonephritis, Acute Renal Failure, Renal Failure, Viral Hepatitis, Alcoholic Hepatitis, Steatohepatitis, Cirrhosis, Asthma, COPD, Bronchitis, Emphysema, Pneumonia, Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis, Diverticulitis, Peptic Ulcer Disease, Irritable Bowel Syndrome, Cholecystitis, Pancreatitis, Malabsorption Disorders, Celiac Sprue, Diabetes
Interventions
Not listed
Lead sponsor
Epic Research & Diagnostics, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
353 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 21, 2011 · Synced Jul 21, 2026, 5:04 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Adherence to Universal Aspirin Compared to Screening Indicated Aspirin for Prevention of Preeclampsia

NCT04797949
View directory record Official record
Conditions
Medication Adherence, Preeclampsia
Interventions
Low-dose aspirin
Drug
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies

NCT07659821
View directory record Official record
Conditions
Pregnant Women With Singleton Pregnancies
Interventions
Food Kit
Other
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
3
States / cities
College Station, Texas • Dallas, Texas • Mansfield, Texas
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 21, 2026, 5:04 AM EDT