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ClinicalTrials.gov public records Last synced Oct 25, 2026, 2:09 AM EDT

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Showing 289–312 of 1,212 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Premature Births Clear all
Terminated Not applicable Interventional

Early Versus Late Caffeine for ELBW Newborns

NCT02524249
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Apnea of Prematurity
Interventions
Caffeine, Placebo (dextrose)
Drug
Lead sponsor
Wayne State University
Other
Eligibility
Up to 4 Weeks
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Phase 3 Interventional Results available

Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide

NCT00569530
View directory record Official record
Conditions
Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction), Bronchopulmonary Dysplasia
Interventions
Infasurf (ONY Inc.), Sham
Drug
Lead sponsor
Roberta Ballard
Other
Eligibility
7 Days to 14 Days
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
9
States / cities
Berkeley, California • Oakland, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 25, 2026, 2:09 AM EDT
Completed No phase listed Observational

Indomethacin PK and PD Therapy in Pregnancy

NCT02451228
View directory record Official record
Conditions
Premature Labor, Pregnancy, Premature Birth
Interventions
Serial blood collection
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
6
States / cities
Birmingham, Alabama • Jackson, Mississippi • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Oct 25, 2026, 2:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Cervix Monitor for Elasticity and Length Measurements

NCT03199079
View directory record Official record
Conditions
Preterm Birth
Interventions
Measurement
Other
Lead sponsor
Advanced Tactile Imaging, Inc.
Industry
Eligibility
21 Years to 44 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
New Brunswick, New Jersey • Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional Results available

Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants

NCT03694613
View directory record Official record
Conditions
Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
Interventions
Placental/Umbilical Cord Blood sample
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 1 Day
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Intraventricular Hemorrhage and Post Hemorrhagic Ventricular Dilation: Natural Course, Treatment, and Outcome

NCT00957840
View directory record Official record
Conditions
Intraventricular Hemorrhage, Premature Infants
Interventions
NIRS, aEEG, and CSF concentration of biomarkers
Procedure
Lead sponsor
University of Utah
Other
Eligibility
Up to 1 Year
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 6, 2015 · Synced Oct 25, 2026, 2:09 AM EDT
Completed No phase listed Observational

Biomarkers of Intra-amniotic Infection in Women With Preterm Premature Ruptured Amniotic Membranes

NCT00701350
View directory record Official record
Conditions
Intra-amniotic Infection, Preterm Birth
Interventions
Not listed
Lead sponsor
ProteoGenix, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
4
States / cities
Phoenix, Arizona • Tucson, Arizona • San Jose, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2010 · Synced Oct 25, 2026, 2:09 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Electrical Inhibition of Human Preterm Contractions

NCT02983240
View directory record Official record
Conditions
Preterm Labor, PreTerm Birth, Preterm Labor With Delivery Nos
Interventions
Electrical Uterine Pacemaker
Device
Lead sponsor
e-Bio Corp
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Feasibility and Validation of a Smart Changing Pad for Home Infant Weight Monitoring After Hospital Discharge

NCT07718516
View directory record Official record
Conditions
Infant Nutrition Disorders, Weight Loss, Postnatal Care, Premature Birth
Interventions
Woddle Smart Changing Pad
Device
Lead sponsor
Stan Kachnowski
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 25, 2026, 2:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alteration of Stool Microbiota in Preterm Infants With Anemia

NCT03554278
View directory record Official record
Conditions
Anemia, Neonatal, Necrotizing Enterocolitis, Dysbiosis
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
7 Days to 30 Days
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Phase 1 Interventional

Early Blood Pressure Management in Extremely Premature Infants

NCT00874393
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Hypotension, Blood Pressure
Interventions
Dopamine, Hydrocortisone, Infusion Placebo, Syringe Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 24 Hours
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated May 25, 2017 · Synced Oct 25, 2026, 2:09 AM EDT
Terminated No phase listed Observational

17-OHPC in Pregnancy: IM vs SC Routes

NCT04183452
View directory record Official record
Conditions
Preterm Birth
Interventions
17-Hydroxyprogesterone Caproate 250 mg IM Dose, 17-Hydroxyprogesterone Caproate 275 mg SC Dose
Drug
Lead sponsor
Steve N. Caritis, MD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
4
States / cities
Newark, Delaware • Durham, North Carolina • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Prebiotic in Preterm Infants

NCT03306316
View directory record Official record
Conditions
Preterm Infant, Development, Infant, Nutrition
Interventions
Prebiotic, Dextrose Control
Dietary Supplement
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
7 Days to 10 Days
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Oct 25, 2026, 2:09 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Preventing Preterm Birth With a Pessary

NCT01380158
View directory record Official record
Conditions
Preterm Birth
Interventions
Cup pessary (Bioteque America, Inc)
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Oct 25, 2026, 2:09 AM EDT
Recruiting Not applicable Interventional

Better Birth Outcomes Through Technology, Education, and Reporting

NCT06261398
View directory record Official record
Conditions
Pregnancy, Maternal Anemia, Pre-Term Birth, Hypertensive Disorders
Interventions
BETTER: motivational interviewing and text messaging, Standard of care
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 25, 2026, 2:09 AM EDT
Enrolling by invitation Not applicable Interventional

The Social Determinants of Health Screening and Referral Project

NCT06582147
View directory record Official record
Conditions
Preterm Birth
Interventions
Implementation of social determinants of health screening and referral
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
882 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
7
States / cities
Denver, Colorado • Jacksonville, Florida • Detroit, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Transpyloric Feeding in Severe Bronchopulmonary Dysplasia

NCT02142621
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
transpyloric feeding, gastric feeding
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
4 Weeks to 24 Weeks
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 25, 2026, 2:09 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Pulmonary Function Using Non-invasive Forced Oscillometry

NCT03346343
View directory record Official record
Conditions
Infant, Premature, Diseases, Infant, Newborn, Diseases, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Newborn, Meconium Aspiration Syndrome, Transient Tachypnea of the Newborn
Interventions
Non-invasive forced airway oscillometry
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 2 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Kangaroo Holding and Maternal Stress

NCT00271115
View directory record Official record
Conditions
Premature Birth, Maternal Stress
Interventions
Kangaroo Holding
Behavioral
Lead sponsor
Christiana Care Health Services
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Feb 17, 2012 · Synced Oct 25, 2026, 2:09 AM EDT
Completed No phase listed Observational

Premature Infant Exposure to Noise Generated by Respiratory Support

NCT01748214
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
7 Days and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 12, 2012 · Synced Oct 25, 2026, 2:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

NCT03906435
View directory record Official record
Conditions
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Routine Versus no Assessment of Gastric Residual Volumes in Preterm Infants

NCT04062851
View directory record Official record
Conditions
Gastric Residual Volume, Preterm Infant, Feeding Disorder Neonatal
Interventions
No Gastric residual volume monitoring
Other
Lead sponsor
AdventHealth
Other
Eligibility
2 Hours to 1 Month
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cue-based Tactile Stimulation and Infant Stress Reactivity

NCT01121523
View directory record Official record
Conditions
Premature; Infant, Light-for-dates
Interventions
Cue directed tactile stimulation
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
7 Days to 4 Months
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Oct 25, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intrapartum Study of Sterile and Clean Gloves

NCT01852188
View directory record Official record
Conditions
Chorioamnionitis
Interventions
Type of glove used for intrapartum vaginal exams
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2018 · Synced Oct 25, 2026, 2:09 AM EDT