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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:41 PM EDT

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Showing 73–96 of 1,212 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Premature Births Clear all
Completed Not applicable Interventional

Noninferiority Trial of Liquid Human Milk Fortifier (HMF) Hydrolyzed Protein Versus Liquid HMF With Supplemental Liquid Protein

NCT03001479
View directory record Official record
Conditions
Human Milk, Premature Birth of Newborn
Interventions
Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid
Dietary Supplement
Lead sponsor
St. Louis University
Other
Eligibility
Up to 2 Weeks
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Phase 3 Interventional Results available

Oral Progesterone for Prevention of Preterm Birth

NCT01180296
View directory record Official record
Conditions
Preterm Birth
Interventions
oral micronized progesterone, Identical Placebo tablet
Drug
Lead sponsor
Fetal Medicine Foundation
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Oct 23, 2026, 1:41 PM EDT
Completed No phase listed Observational

Prematurity-Related Ventilatory Control

NCT03464396
View directory record Official record
Conditions
Respiratory Control in Premature Infants
Interventions
Bedside Physiology study, Carotid Body Function Test, Room Air Challenge, Hypoxia Challenge Test, Effects of Nasal Cannula Flow, Magnetic Resonance Imaging, Echocardiogram, Blood Sample
Other · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Day to 28 Days
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Oct 23, 2026, 1:41 PM EDT
Recruiting Phase 1 Interventional

Neonatal White Matter Injury Trial (WRAP)

NCT07688746
View directory record Official record
Conditions
White Matter Injury, Brain Injury, Fetus and Neonate, Neonatal Brain Injury, Periventricular Leukomalacia, Periventricular White Matter Abnormalities
Interventions
Clemastine fumarate
Drug
Lead sponsor
Bridget LaMonica Ostrem, M.D., Ph.D.
Other
Eligibility
3 Weeks to 20 Weeks
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Supplementation of Fluoride on Maternal Periodontal Health, Preterm Delivery, and Perinatal Well-Being

NCT02536352
View directory record Official record
Conditions
Preterm Birth, Preterm Labor, Bacteremia, Preterm Premature Rupture of Fetal Membranes
Interventions
Prenatal vitamin-mineral containing 3 mg fluoride, Prenatal vitamin-mineral containing 0 mg fluoride
Drug · Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Oct 23, 2026, 1:41 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Postoperative Pain Control & Relief in Neonates

NCT03677830
View directory record Official record
Conditions
Pain, Postoperative, Premature Infant, Opioid Use
Interventions
Acetaminophen, Saline
Drug
Lead sponsor
St. Louis University
Other
Eligibility
Up to 1 Month
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2024 · Synced Oct 23, 2026, 1:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pulse Oximetry Performance Comparison in Newborns

NCT06637917
View directory record Official record
Conditions
Newborn, Birth, Preterm
Interventions
OxySoftN™ Neonatal-Adult SpO2 Sensor with N600X Nellcor™ Patient Monitoring System, LNCS® NEO SpO2 Sensor with RAD-97™ Pulse CO-Oximeter, 1041PTS (or similar) Kendall™ Neonatal Electrodes with IntelliVue MP5 Portable Patient Monitor
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
29 Weeks and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Los Angeles, California • St Louis, Missouri • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 23, 2026, 1:41 PM EDT
Completed No phase listed Observational

Work of Breathing and Kangaroo Mother Care

NCT03683316
View directory record Official record
Conditions
Premature Infant, Work of Breathing, Oxygen Saturation
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
4 Days to 6 Months
Enrollment
29 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Not applicable Interventional Results available

Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function

NCT04295564
View directory record Official record
Conditions
Neonatal, Premature Birth, Respiratory Distress Syndrome
Interventions
Additional 2 weeks of CPAP
Other
Lead sponsor
Cynthia McEvoy
Other
Eligibility
1 Day to 12 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 23, 2026, 1:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy

NCT06965530
View directory record Official record
Conditions
Pregnancy Related, Prematurity, Birth Outcome, Adverse
Interventions
Clinic-Based Medically Tailored Groceries (CB-MTG), Home Delivered Medically Tailored Groceries (HD-MTG), Home Delivered Medically Tailored Groceries plus Education (HD-MTG_PLUS)
Dietary Supplement
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 23, 2026, 1:41 PM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Hormone Replacement for Premature Ovarian Insufficiency

NCT02922348
View directory record Official record
Conditions
Primary Ovarian Insufficiency
Interventions
Hormone Replacement Therapy, Combined Oral Contraceptives
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
14 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Severe Intrauterine Growth Retardation: Developmental Newborn Intensive Care Unit (NICU) Care

NCT00914108
View directory record Official record
Conditions
Intrauterine Growth Retardation, Prematurity
Interventions
Newborn Individualized Developmental Care
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 36 Weeks
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2002
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 23, 2026, 1:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs

NCT04301518
View directory record Official record
Conditions
Preterm Labor, Preterm Birth
Interventions
Multimodal intervention strategy
Other
Lead sponsor
Sera Prognostics, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
6,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
18
States / cities
San Diego, California • New Haven, Connecticut • Newark, Delaware + 15 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Not applicable Interventional Results available

Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator

NCT01440647
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Extubation to NIPPV, Extubation to CPAP
Procedure
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Up to 48 Hours
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 12, 2013 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Supporting and Enhancing NICU Sensory Experiences (SENSE)

NCT03316547
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
SENSE Program
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 32 Weeks
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Not applicable Interventional Results available

A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants

NCT03298035
View directory record Official record
Conditions
Apnea of Prematurity
Interventions
NCPAP as mode for apnea prevention, NIPPV as rescue mode for apnea prevention
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 23, 2026, 1:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Ovarian Function Following Intraovarian Injection of PRP

NCT04278313
View directory record Official record
Conditions
Diminished Ovarian Reserve, Diminished Ovarian Reserve Due to Advanced Maternal Age
Interventions
PRP - Platelet Rich Plasma, PPP - Platelet Poor Plasma
Procedure
Lead sponsor
Center for Human Reproduction
Other
Eligibility
21 Years to 44 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Phase 2 Interventional Results available

Recombinant Human Prolactin for Lactation Induction

NCT00181610
View directory record Official record
Conditions
Lactation
Interventions
Recombinant Human Prolactin, Recombinant human prolactin, Normal Saline
Drug · Biological
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 3, 2018 · Synced Oct 23, 2026, 1:41 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Microbiome And Multi'Omics In Preterm Birth: The Bacteria And Birth Study

NCT02392650
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
16 Years to 64 Years
Enrollment
526 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Effect of Selenium Supplementation on Trace Mineral Antioxidant Enzyme and Amino Acid Metabolism in Infants

NCT02066610
View directory record Official record
Conditions
Preterm Infants
Interventions
selenium and sodium selenate supplementation, selenium and sodium selenite supplementation, Without selenium and sodium selenate supplementation, Without selenium and sodium selenite supplementation
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 1993
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 19, 2014 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants

NCT01758913
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
Ibuprofen
Drug
Lead sponsor
Taipei Medical University Hospital
Other
Eligibility
Up to 6 Months
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Oct 23, 2026, 1:41 PM EDT
Active, not recruiting No phase listed Observational

Microbiome, Atopic Disease, Prematurity

NCT04835935
View directory record Official record
Conditions
Atopy, Prematurity
Interventions
microbiome pattern
Other
Lead sponsor
Sydney Leibel
Other
Eligibility
0 Days to 7 Days
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 23, 2026, 1:41 PM EDT
Completed Phase 2Phase 3 Interventional

Assessment Of Efficacy and Safety UK-390,957 In Men With Premature Ejaculation

NCT00219635
View directory record Official record
Conditions
Ejaculation
Interventions
UK-390,957
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older · Male only
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
14
States / cities
Birmingham, Alabama • San Bernardino, California • Metairie, Louisiana + 11 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2012 · Synced Oct 23, 2026, 1:41 PM EDT
Active, not recruiting Not applicable Interventional

ViDES Trial (Vitamin D Extra Supplementation)

NCT05459298
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Placebo, 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth, Usual Care
Dietary Supplement · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
24 Hours to 96 Hours
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 23, 2026, 1:41 PM EDT