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ClinicalTrials.gov public records Last synced Oct 24, 2026, 6:20 AM EDT

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Showing 169–192 of 1,212 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Premature Births Clear all
Recruiting Not applicable Interventional

Targeted Fortification of Donor Breast Milk in Preterm Infants

NCT04294368
View directory record Official record
Conditions
Prematurity; Extreme, Failure to Thrive in Newborn, Growth Retardation, Growth Failure, Infant Nutrition Disorders
Interventions
Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid, Similac Liquid Protein Fortifier, Nestle Microlipid, Medica Nutrition SolCarb, Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid (Targeted Fortification), Similac Liquid Protein Fortifier (Targeted Fortification), Nestle Microlipid (Targeted Fortification), Medica Nutrition SolCarb (Targeted Fortification), Analysis with Miris (AB) Human Milk Analyzer
Dietary Supplement · Other
Lead sponsor
Columbia University
Other
Eligibility
1 Day to 21 Days
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 24, 2026, 6:20 AM EDT
Completed No phase listed Observational

Study to Evaluate the Incidence of Hospitalizations and Respiratory Tract Infections in Premature Infants

NCT00384462
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
Not listed
Lead sponsor
MedImmune LLC
Industry
Eligibility
1 Month to 6 Months
Enrollment
346 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
59
States / cities
Birmingham, Alabama • Benton, Arkansas • Jonesboro, Arkansas + 50 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2009 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

PREGNANT Short Cervix Trial

NCT00615550
View directory record Official record
Conditions
Preterm Delivery, Short Cervix, Short Uterine Cervical Length
Interventions
progesterone, placebo
Drug
Lead sponsor
Juniper Pharmaceuticals, Inc.
Industry
Eligibility
15 Years to 45 Years · Female only
Enrollment
465 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
27
States / cities
Mobile, Alabama • Phoenix, Arizona • Orange, California + 21 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2012 · Synced Oct 24, 2026, 6:20 AM EDT
Active, not recruiting Not applicable Interventional

Randomized Trial of Enteral Vitamin D Supplementation in Infants < 28 Weeks Gestational Age or <1000 Grams Birth Weight

NCT05694689
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Placebo, 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth, Usual Care
Dietary Supplement · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
24 Hours to 96 Hours
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 24, 2026, 6:20 AM EDT
Terminated No phase listed Observational

Exenatide Pregnancy Registry - Type 2 Diabetes in Pregnancy

NCT00579150
View directory record Official record
Conditions
Birth Defects, Type 2 Diabetes, Preterm Birth
Interventions
Not listed
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Oct 24, 2026, 6:20 AM EDT
Completed No phase listed Observational

Impact of Treatment Induced Premature Menopause on Quality of Life

NCT00185718
View directory record Official record
Conditions
Menopause, Premature
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2012 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2)

NCT01030575
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Bronchopulmonary Dysplasia (BPD)
Interventions
Inositol lower volume, Inositol mid-level volume, Inositol high volume, Placebo low volume
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
12 Hours to 72 Hours
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of Immediate vs. Delayed Cord Clamping in the Preterm Neonate

NCT00579839
View directory record Official record
Conditions
PreTerm Birth, PreTerm Neonate
Interventions
Delayed Cord Clamping, Immediate Cord Clamping
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 20, 2012 · Synced Oct 24, 2026, 6:20 AM EDT
Recruiting Not applicable Interventional

Humidity in Incubators for Tiny Infants

NCT06399861
View directory record Official record
Conditions
Extremely Premature Infant
Interventions
Higher (90%) starting RH in the incubator with humidity supplementation stopped at day 10, Lower (70%) starting RH in the incubator with humidity supplementation stopped at day 10, Higher (90%) starting RH in the incubator with humidity supplementation stopped at day 28, Lower (70%) starting RH in the incubator with humidity supplementation stopped at day 28
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
0 Days to 1 Day
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
9
States / cities
Birmingham, Alabama • San Diego, California • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 24, 2026, 6:20 AM EDT
Completed No phase listed Observational

Fetal Anatomy by Three-Dimensional Ultrasound

NCT00340002
View directory record Official record
Conditions
Preterm Birth, Pregnancy, Fetal Growth Abnormalities
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
3,650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2016
U.S. locations
2
States / cities
Detroit, Michigan • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Plastic Hat Trial to Prevent Hypothermia in Preterm Newborns in the Delivery Room

NCT00904228
View directory record Official record
Conditions
Hypothermia
Interventions
placement of plastic cap during delivery room stabilization, placement of routine cap during delivery room stabilization
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 1 Hour
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 24, 2026, 6:20 AM EDT
Recruiting No phase listed Observational

Generic Database of Very Low Birth Weight Infants

NCT00063063
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
No Intervention
Other
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 14 Days
Enrollment
80,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1987 – 2030
U.S. locations
31
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 26 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 24, 2026, 6:20 AM EDT
Completed No phase listed Observational

Nasogastric/Orogastric Tube Placement Confirmation in Neonates Utilizing Self-contained pH Device, a Feasibility Study

NCT06274944
View directory record Official record
Conditions
Premature Birth
Interventions
nasogastric tube placement pH confirmation device
Device
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 2 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Phase 3 Interventional Results available

Follow up Study to Assess Long Term Safety and Outcomes in Infants and Children Born to Mothers Participating in Retosiban Treatment Studies

NCT02292784
View directory record Official record
Conditions
Obstetric Labour, Premature
Interventions
Retosiban, Atosiban, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
10 Weeks to 20 Weeks
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Park Ridge, Illinois • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Not applicable Interventional

Sustained Auricular Nerve Stimulation for PVC Suppression

NCT07093034
View directory record Official record
Conditions
Premature Ventricular Complexes, PVC - Premature Ventricular Contraction, Auricular Vagus Nerve Stimulation
Interventions
Extended nocturnal use of auricular vagus nerve stimulator device
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Not applicable Interventional Results available

Cord Clamping Level Above or Below Mother's Perineum

NCT02659605
View directory record Official record
Conditions
Pre-term Birth, Delayed Cord Clamping
Interventions
Delayed cord clamping above the perineum, Delayed cord clamping below the perineum
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 24, 2026, 6:20 AM EDT
Completed No phase listed Observational Results available

NIRS Monitoring to Detect AKI in Preterm Infants

NCT03384173
View directory record Official record
Conditions
Acute Kidney Injury, Premature Infant
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
1 Minute to 7 Days
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)

NCT00724594
View directory record Official record
Conditions
Chorioamnionitis, Brain Injury
Interventions
N-acetylcysteine, Control
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Oct 24, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Postpartum Contraception in Women With Preterm Births

NCT01864629
View directory record Official record
Conditions
Method of Contraception, Preterm Birth Recurrence
Interventions
Focused contraception counseling
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
14 Years to 50 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 24, 2026, 6:20 AM EDT
Terminated Phase 4 Interventional

Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates

NCT00961753
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
optimized ibuprofen, Standard Ibuprofen
Drug
Lead sponsor
OSF Healthcare System
Other
Eligibility
1 Day to 29 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Oct 24, 2026, 6:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pain and Stress Assessment and ROP Screening

NCT02415205
View directory record Official record
Conditions
Pain, Stress
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2018 · Synced Oct 24, 2026, 6:20 AM EDT
Terminated Not applicable Interventional Results available

Interventions to Help Infants Recover in the Hospital

NCT03881553
View directory record Official record
Conditions
Infant Apnea, Neonatal Abstinence Syndrome, Sleep
Interventions
NEATCAP, SVS mattress
Device
Lead sponsor
Elisabeth Salisbury, PhD
Other
Eligibility
2 Days to 3 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Oct 24, 2026, 6:20 AM EDT
Recruiting Phase 3 Interventional

PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

NCT07232069
View directory record Official record
Conditions
Coronary Artery Disease Risk Factors Multiple, Coronary Artery Disease Progression, Prevention & Control, Premature Atherosclerosis
Interventions
Rosuvastatin 20 Mg Oral Tablet, Colchicine 0.5 MG Oral Tablet Once Daily, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
30 Years to 60 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
23
States / cities
Birmingham, Alabama • Mobile, Alabama • Los Angeles, California + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 24, 2026, 6:20 AM EDT
Terminated Not applicable Interventional Results available

Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure

NCT00833365
View directory record Official record
Conditions
Patent Ductus Arteriosus, Prematurity
Interventions
Ibuprofen
Drug
Lead sponsor
University of Utah
Other
Eligibility
Up to 96 Hours
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 4, 2016 · Synced Oct 24, 2026, 6:20 AM EDT