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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:59 PM EDT

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Showing 145–168 of 851 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Premature Infant Clear all
Completed Not applicable Interventional

Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants

NCT00875758
View directory record Official record
Conditions
Intraventricular Hemorrhage, Hydrocephalus
Interventions
Removal of CSF through ventricular access device, Removal of CSF through a ventricular access device
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 34 Weeks
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development

NCT02639676
View directory record Official record
Conditions
Preeclampsia
Interventions
Diffusion Lung Capacity (DLCO), Vascular Challenge, Video Imaging, Specimen Collections
Other
Lead sponsor
Indiana University
Other
Eligibility
26 Weeks and older
Enrollment
292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Evaluating Decisional Regret Among Mothers

NCT04074525
View directory record Official record
Conditions
Extreme Prematurity, Birth, Preterm, Pregnancy Preterm
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older · Female only
Enrollment
211 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Phase 2 Interventional

Early Protein Supplementation of Human Milk in Extremely Low Birth Weight Infants

NCT01991613
View directory record Official record
Conditions
Growth in Premature Infants
Interventions
liquid protein supplement
Dietary Supplement
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
26 Weeks to 33 Weeks
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Effective Fraction of Inspired Oxygen With Nasal Cannula in Premature Infants

NCT03431818
View directory record Official record
Conditions
Oxygen Therapy
Interventions
Nasal cannula flow rate
Other
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Not applicable Interventional

VentFirst Pilot: Ventilating Preterm Infants During Delayed Cord Clamping

NCT02391389
View directory record Official record
Conditions
Infant, Premature, Diseases
Interventions
CPAP or PPV during DCC
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Phase 2 Interventional Results available

Safety of Sildenafil in Premature Infants

NCT03142568
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Sildenafil, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Days to 28 Days
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
14
States / cities
Little Rock, Arkansas • Jacksonville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 21, 2026, 7:59 PM EDT
Withdrawn Not applicable Interventional

Use of Prokinetics in Early Enteral Feeding in Preterm Infants

NCT01569633
View directory record Official record
Conditions
Feeding Disorder, Nutrition Disorder, Infant,Premature
Interventions
Metclopramide, Erythromycin, placebo
Drug
Lead sponsor
East Tennessee State University
Other
Eligibility
Up to 14 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Assessment of the Pulmonary Diffusion Capacity in Healthy Infants and Infants With Chronic Lung Disease

NCT00428038
View directory record Official record
Conditions
Infant, Premature, Bronchopulmonary Dysplasia, Asthma
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
2 Months to 2 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 30, 2012 · Synced Oct 21, 2026, 7:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Warming in Preterm Infants to Decrease Hypothermia

NCT05170633
View directory record Official record
Conditions
Preterm Birth, Blood Transfusion Complication, Hypothermia
Interventions
Ranger blood warmer (3M Healthcare, Oakdale, Minnesota)
Device
Lead sponsor
University of South Carolina
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Oct 21, 2026, 7:59 PM EDT
Active, not recruiting No phase listed Observational

Effects of Transitional Circulation in ELBW Infants

NCT02016599
View directory record Official record
Conditions
Neonatal Prematurity, Hypotension
Interventions
Monitoring and biospecimen collection
Other
Lead sponsor
University of Iowa
Other
Eligibility
Up to 1 Week
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2032
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Phase 3 Interventional Results available

RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity

NCT02375971
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Ranibizumab, Laser therapy
Drug · Procedure
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
12
States / cities
Loma Linda, California • Sacramento, California • Aurora, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Phase 2Phase 3 Interventional

Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome

NCT01203358
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Bronchopulmonary Dysplasia
Interventions
Exosurf, Survanta
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 6 Hours
Enrollment
617 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 1992
U.S. locations
13
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Oral Entrainment on Suck Development of Preterm Infants Born 23 to 34 Weeks Gestational Age (GA)

NCT01069744
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
KC BioMediX, Inc
Industry
Eligibility
23 Weeks to 34 Weeks
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2010 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Work of Breathing and Kangaroo Mother Care

NCT03683316
View directory record Official record
Conditions
Premature Infant, Work of Breathing, Oxygen Saturation
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
4 Days to 6 Months
Enrollment
29 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia

NCT01748565
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Prematurity
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Up to 7 Days
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Indianapolis, Indiana • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 21, 2026, 7:59 PM EDT
Active, not recruiting Phase 2 Interventional

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

NCT03253263
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Intraventricular Hemorrhage, Retinopathy of Prematurity (ROP)
Interventions
OHB-607
Drug
Lead sponsor
OHB Neonatology Ltd.
Industry
Eligibility
0 Hours to 24 Hours
Enrollment
295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
24
States / cities
Little Rock, Arkansas • California City, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Phase 2 Interventional

18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study

NCT01426698
View directory record Official record
Conditions
Developmental Delay
Interventions
delayed cord clamping
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
24 Weeks to 31 Weeks
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 5, 2014 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

Electrical Activity of Diaphragm as a Means to Predict Extubation Success in Preterm Infants

NCT02144363
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Not listed
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
1 Hour to 28 Days
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 11, 2016 · Synced Oct 21, 2026, 7:59 PM EDT
Not yet recruiting Phase 1 Interventional

Breast-milk Enema Administration to Stimulate Passage of Meconium

NCT07661992
View directory record Official record
Conditions
Breast-milk
Interventions
breast milk
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Not applicable Interventional Results available

Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention

NCT02153736
View directory record Official record
Conditions
Infant, Premature, Diseases, Brain White Matter Disease Periventricular
Interventions
SPEEDI Intervention
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
Up to 18 Weeks
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

NICU-HEALTH (Hospital Exposures and Long-Term Health)

NCT01963065
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 1 Year
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 21, 2026, 7:59 PM EDT
Completed Phase 1 Interventional

Feasibility Study of SPEEDI

NCT01889108
View directory record Official record
Conditions
Premature
Interventions
SPEEDI
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
Up to 34 Weeks
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Oct 21, 2026, 7:59 PM EDT
Completed No phase listed Observational

39946-I Laser and Bevacizumab Treatment for Retinopathy of Prematurity

NCT01993043
View directory record Official record
Conditions
ROP Threshold
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
30 Weeks to 40 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
2
States / cities
Houston, Texas • Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 21, 2026, 7:59 PM EDT