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ClinicalTrials.gov public records Last synced Jul 20, 2026, 6:42 PM EDT

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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Premature Ventricular Contraction (PVC) Clear all
Enrolling by invitation Not applicable Interventional

Sustained Auricular Nerve Stimulation for PVC Suppression

NCT07093034
View directory record Official record
Conditions
Premature Ventricular Complexes, PVC - Premature Ventricular Contraction, Auricular Vagus Nerve Stimulation
Interventions
Extended nocturnal use of auricular vagus nerve stimulator device
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Enrolling by invitation Not applicable Interventional

Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)

NCT06964152
View directory record Official record
Conditions
Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC), Ventricular Fibrillation
Interventions
Computational electrocardiography and cardiac computed tomography mapping
Diagnostic Test
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 90 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2034
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated No phase listed Observational

SHERLOCK 3CG™ Diamond Tip Confirmation System

NCT03288766
View directory record Official record
Conditions
Indication for Peripheral Intravenous Catheterization, Atrial Flutter, Premature Atrial Contraction, Premature Ventricular Contraction, Premature Junctional Contraction, Tachycardia, Atrioventricular Block, Bundle-Branch Block
Interventions
PICC placement with SHERLOCK 3CG™ Diamond TCS with MODUS II software
Procedure
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years and older
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
6
States / cities
Las Vegas, Nevada • Greensboro, North Carolina • Greenville, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Jul 20, 2026, 6:42 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

NCT03218137
View directory record Official record
Conditions
Premature Ventricular Contraction (PVC)
Interventions
Adenosine
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Enrolling by invitation Not applicable Interventional

Treatment of Focal Ventricular Tachycardias Using a Pulsed Field Ablation From a Point Ablation Catheter Short Title FOCUS-PFA

NCT06747013
View directory record Official record
Conditions
Focal Ventricular Arrhythmias, Premature Ventricular Contractions, Ventricular Tachycardias
Interventions
Point Ablation Catheter
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The MARY-JANE Cannabis and Heart Rhythm Trial

NCT06021613
View directory record Official record
Conditions
Premature Atrial Contractions, Premature Ventricular Contractions
Interventions
Randomized instructions
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2025 · Synced Jul 20, 2026, 6:42 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

NCT00921986
View directory record Official record
Conditions
Arrhythmias, Cardiac
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2035
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Phase 4 Interventional Results available

DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation

NCT02666742
View directory record Official record
Conditions
Ventricular Tachycardia, Premature Ventricular Contraction, Stroke
Interventions
DOAC, Aspirin
Drug
Lead sponsor
Kansas City Heart Rhythm Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Kansas City, Kansas • Overland Park, Kansas • The Bronx, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Jul 20, 2026, 6:42 PM EDT
Recruiting No phase listed Observational

Role of Novel ILR in the Management of PVCs

NCT06060548
View directory record Official record
Conditions
PVC - Premature Ventricular Contraction, Myocarditis
Interventions
Monitoring of patients presenting with PVCs
Other
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2022 – 2025
U.S. locations
6
States / cities
Overland Park, Kansas • Independence, Missouri • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 20, 2026, 6:42 PM EDT
Completed No phase listed Observational Results available

EnSite Precision Observational Study

NCT03260244
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
cardiac mapping and radiofrequency ablation procedure
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,065 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
7
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Jul 20, 2026, 6:42 PM EDT
Not listed Phase 4 Interventional

Study to Reduce Symptoms of Premature Beats With Ranolazine

NCT01996618
View directory record Official record
Conditions
Premature Ventricular Beats
Interventions
Ranolazine
Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Jul 20, 2026, 6:42 PM EDT
Not listed Phase 4 Interventional

Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)

NCT03228823
View directory record Official record
Conditions
Ventricular Premature Beats, Contractions, or Systoles, Cardiomyopathies
Interventions
Radiofrequency ablation, Amiodarone (Antiarrhythmic drug)
Procedure · Drug
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
10
States / cities
Los Angeles, California • San Francisco, California • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Jul 20, 2026, 6:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Heart Rhythm Twins Study

NCT05866731
View directory record Official record
Conditions
Premature Atrial Complex, Premature Ventricular Contraction
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated Not applicable Interventional Results available

Early Elimination of Premature Ventricular Contractions in Heart Failure

NCT01757067
View directory record Official record
Conditions
Premature Ventricular Contractions, Congestive Heart Failure
Interventions
PVC ablation
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
7
States / cities
Los Angeles, California • Baltimore, Maryland • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Jul 20, 2026, 6:42 PM EDT
Completed No phase listed Observational

Electrocardiographic Diagnostic Performance of the Apple Watch Augmented With an Artificial Intelligence Algorithm

NCT05167058
View directory record Official record
Conditions
Atrial Fibrillation, Tachycardia, Bradycardia, Premature Supraventricular Beat, Premature Ventricular Contraction
Interventions
Cardiologs Platform
Device
Lead sponsor
Cardiologs Technologies
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Hackensack, New Jersey • Ridgewood, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Jul 20, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

NCT07220525
View directory record Official record
Conditions
Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC), Atrial Fibrillation (AF), Premature Atrial Contraction
Interventions
HGNS Use Randomized Instructions
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Phase I/II Study of EP-guided Noninvasive Cardiac Radioablation for Treatment of Ventricular Tachycardia

NCT02919618
View directory record Official record
Conditions
Ventricular Tachycardia, Cardiomyopathy, Premature Ventricular Contractions
Interventions
stereotactic body radiotherapy (SBRT)
Radiation
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Jul 20, 2026, 6:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of MIBG Scan Images in PVC Ablations

NCT02279030
View directory record Official record
Conditions
Premature Ventricular Contractions
Interventions
MIBG nuclear scan
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Jul 20, 2026, 6:42 PM EDT
Withdrawn Phase 3 Interventional

Vagal Nerve Stimulation as an Alternative Therapy for Premature Ventricular Contractions

NCT06110364
View directory record Official record
Conditions
Premature Ventricular Contraction
Interventions
Low-Level Tragus Stimulation, Heart Rate Variability- Biofeedback, Conventional Medical Therapy
Device · Behavioral · Other
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Phase 2 Interventional Results available

Ranolazine Mediated PVC Reduction in Ischemic Heart Disease

NCT02360397
View directory record Official record
Conditions
Ventricular Premature Complexes, Myocardial Ischemia
Interventions
ranolazine
Drug
Lead sponsor
Kent Hospital, Rhode Island
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Jul 20, 2026, 6:42 PM EDT
Terminated Phase 2 Interventional Results available

Premature Ventricular Contractions (PVCs) and Blood Pressure Control

NCT01833455
View directory record Official record
Conditions
Ventricular Premature Complexes, Blood Pressure
Interventions
PVC Suppression using Flecainide, No PVC Suppression using Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional

VIVO™ Accuracy Study

NCT03340142
View directory record Official record
Conditions
Premature Ventricular Contraction, Ventricular Tachycardia
Interventions
VIVO™
Device
Lead sponsor
Catheter Precision. Inc.
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Iowa City, Iowa • Baltimore, Maryland • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Jul 20, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Evaluation of a Test Algorithm for Use to Analyze ECG Data Collected From a Test Device of a 24-hour Simulated Use Period

NCT07188129
View directory record Official record
Conditions
Atrial Fibrillation (AF), Tachycardia, Bradycardia, PVC - Premature Ventricular Contraction, Premature Atrial Contraction
Interventions
Test Algorithm and Test Device
Device
Lead sponsor
Zywie, Inc.
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Jul 20, 2026, 6:42 PM EDT
Recruiting No phase listed Observational

Defining the Risk of Ventricular Tachycardia in Genetic Cardiomyopathies

NCT06575881
View directory record Official record
Conditions
Atrial Fibrillation, Ventricular Tachycardia, Premature Ventricular Contraction
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 20, 2026, 6:42 PM EDT