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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prematurity Complications Clear all
Terminated Not applicable Interventional Results available

Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure

NCT00833365
View directory record Official record
Conditions
Patent Ductus Arteriosus, Prematurity
Interventions
Ibuprofen
Drug
Lead sponsor
University of Utah
Other
Eligibility
Up to 96 Hours
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 3, 2016 · Synced Sep 28, 2026, 1:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Novel Mechanisms and Approaches to Treat Neonatal Sepsis

NCT02554630
View directory record Official record
Conditions
Complication of Prematurity, Immunologic Deficiency Syndromes
Interventions
Adjuvant, Blood Collection
Other
Lead sponsor
University of Florida
Other
Eligibility
Up to 55 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 28, 2026, 1:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy

NCT06965530
View directory record Official record
Conditions
Pregnancy Related, Prematurity, Birth Outcome, Adverse
Interventions
Clinic-Based Medically Tailored Groceries (CB-MTG), Home Delivered Medically Tailored Groceries (HD-MTG), Home Delivered Medically Tailored Groceries plus Education (HD-MTG_PLUS)
Dietary Supplement
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional

The Australian Placental Transfusion Study (APTS): Should Very Pre Term Babies Receive a Placental Blood Transfusion at Birth Via Deferring Cord Clamping Versus Standard Cord Clamping Procedures?

NCT02606058
View directory record Official record
Conditions
Preterm Birth
Interventions
Deferred cord clamping
Procedure
Lead sponsor
University of Sydney
Other
Eligibility
Female only
Enrollment
1,637 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
2
States / cities
Houston, Texas • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Sep 28, 2026, 1:09 PM EDT
Recruiting No phase listed Observational

Follow-up Visit of High Risk Infants

NCT00009633
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
No Intervention
Other
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
18 Months to 26 Months
Enrollment
68,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2030
U.S. locations
31
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 28, 2026, 1:09 PM EDT
Completed No phase listed Observational

Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies

NCT01607216
View directory record Official record
Conditions
Prematurity, Symptomatic Respiratory Disease, Bronchopulmonary Dysplasia
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
Up to 7 Days
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Buffalo, New York • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy

NCT03230032
View directory record Official record
Conditions
Infant Development, Infant,Premature, Hydrocephalus, Neonatal Encephalopathy, Infarction, PVL, Thrombosis, Intraventricular Hemorrhage
Interventions
pacifier-activated device
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
32 Weeks to 12 Months
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 28, 2026, 1:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of Standards for the New Ballard Maturation Score

NCT01203449
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Pregnancy
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
1,090 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 1996
U.S. locations
11
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2015 · Synced Sep 28, 2026, 1:09 PM EDT
Recruiting No phase listed Observational

Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation

NCT07777744
View directory record Official record
Conditions
Ventricular Tachycardia (VT), Premature Ventricular Complexes
Interventions
Not listed
Lead sponsor
University Hospital, Basel, Switzerland
Other
Eligibility
18 Years and older
Enrollment
15,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Michigan Center, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional Results available

Time to Accurate Heart Rate on Neonatal Outcomes

NCT04587934
View directory record Official record
Conditions
Premature Infant, Extremely Low Birth Weight, Extreme Prematurity
Interventions
iRes Warmer with ResusView, iRes Warmer without ResusView
Device · Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 32 Weeks
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Sep 28, 2026, 1:09 PM EDT
Withdrawn Not applicable Interventional

Use of Prokinetics in Early Enteral Feeding in Preterm Infants

NCT01569633
View directory record Official record
Conditions
Feeding Disorder, Nutrition Disorder, Infant,Premature
Interventions
Metclopramide, Erythromycin, placebo
Drug
Lead sponsor
East Tennessee State University
Other
Eligibility
Up to 14 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Sep 28, 2026, 1:09 PM EDT
Terminated Not applicable Interventional

Physical Exam Indicated Cerclage in Twin Gestations

NCT02490384
View directory record Official record
Conditions
Twin Pregnancy, Antepartum Condition or Complication, Preterm Birth, Cervical Dilation Premature
Interventions
Physical exam indicated cerclage
Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Albany, New York • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2020 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional

Serum 25-hydroxy Vitamin D [25(OH)D] Levels, Supplemental Vitamin D, and Parathyroid Hormone Levels in Premature Infants

NCT01469650
View directory record Official record
Conditions
Premature Infants
Interventions
cholecalciferal, cholecalciferol
Dietary Supplement
Lead sponsor
University of Nebraska
Other
Eligibility
23 Weeks to 32 Weeks
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Phase 4 Interventional Results available

Use of Nitrous Oxide Donor for Labor Induction in Women With PreEclampsia

NCT03171480
View directory record Official record
Conditions
Preeclampsia, Labor, Premature
Interventions
Monoket Pill, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Sep 28, 2026, 1:09 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Uterine Contractions Under Blue Light

NCT03691740
View directory record Official record
Conditions
Preterm Contractions
Interventions
Ocular light
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2018 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants

NCT01783041
View directory record Official record
Conditions
Prematurity, Neurodevelopmental Disorder, Carnitine Deficiency
Interventions
L-carnitine, 5% Dextrose
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
1 Day to 3 Days
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yoga in the NICU for Parents Study

NCT05322161
View directory record Official record
Conditions
Postpartum Depression, Anxiety, Depression, Stress Disorder, Prematurity
Interventions
yoga classes
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Not listed
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Cerclage On LOw Risk Singletons: Cervical Cerclage for Prevention of Spontaneous Preterm Birth in Low Risk Singleton Pregnancies With Short Cervix

NCT03251729
View directory record Official record
Conditions
Premature Birth
Interventions
Cervical cerclage, Vaginal progesterone
Procedure · Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional

The FOUNDATION Study

NCT03939546
View directory record Official record
Conditions
Preterm Infant
Interventions
B. infantis EVC001
Other
Lead sponsor
Evolve BioSystems, Inc.
Industry
Eligibility
Up to 10 Days
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes

NCT04633551
View directory record Official record
Conditions
Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
Interventions
Anti-inflammatory supplement
Dietary Supplement
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 28, 2026, 1:09 PM EDT
Terminated Not applicable Interventional

Vaginal Pessary Versus Expectant Management for Placenta Previa

NCT01996345
View directory record Official record
Conditions
Placenta Previa
Interventions
Cervical Pessary Placement
Procedure
Lead sponsor
Pediatrix
Other
Eligibility
18 Years to 54 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
10
States / cities
Mobile, Alabama • Long Beach, California • San Jose, California + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Phase 2 Interventional Results available

Improving Right Ventricular Function in Young Adults Born Preterm

NCT03696758
View directory record Official record
Conditions
Infant,Premature
Interventions
Pulmonary Function Testing, Electrocardiogram, Cardiac Magnetic Resonance Imaging, Metoprolol, Sildenafil
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 28, 2026, 1:09 PM EDT
Completed Not applicable Interventional

Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants

NCT02126501
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Gradual pressure wean
Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
26 Weeks to 32 Weeks
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 7, 2016 · Synced Sep 28, 2026, 1:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Skin Maturation in Premature Infants

NCT01619228
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
24 Weeks to 43 Weeks
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2020 · Synced Sep 28, 2026, 1:09 PM EDT