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ClinicalTrials.gov public records Last synced Oct 26, 2026, 1:12 PM EDT

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Showing 1–24 of 75 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Prematurity of Fetus Clear all
Completed Phase 2 Interventional Results available

The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor

NCT00404768
View directory record Official record
Conditions
Obstetric Labour, Premature
Interventions
GSK221149A, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
32
States / cities
Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 26 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Oct 26, 2026, 1:12 PM EDT
Terminated No phase listed Observational

The Use of Fetal Fibronectin to Predict Delivery Due to Abruptio Placenta

NCT01279369
View directory record Official record
Conditions
Pregnancy Related, Trauma, Abruptio Placentae
Interventions
Not listed
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 26, 2026, 1:12 PM EDT
Not listed No phase listed Observational

PROMComplete for Determination of Rupture of Fetal Membranes

NCT02369601
View directory record Official record
Conditions
Fetal Membranes, Premature Rupture
Interventions
non- intervention study
Other
Lead sponsor
Pro-Lab Diagnostics
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
6
States / cities
Birmingham, Alabama • Indianapolis, Indiana • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 26, 2026, 1:12 PM EDT
Completed Not applicable Interventional

Does Fetal Fibronectin and Ultrasound Cervical Length Help in the Evaluation of Women With Suspected Preterm Labor?

NCT00371046
View directory record Official record
Conditions
Preterm Birth
Interventions
Transvaginal ultrasound cervical length, Cervicovaginal fetal fibronectin
Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2007 · Synced Oct 26, 2026, 1:12 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Study to Support Fetal Heart Rate and Uterine Contraction for Preterm Labor in Singleton and Multiple Pregnancies

NCT01360905
View directory record Official record
Conditions
Pre Term Labor, Multiple Pregnancy
Interventions
Not listed
Lead sponsor
Monica Healthcare Ltd
Industry
Eligibility
17 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2014 · Synced Oct 26, 2026, 1:12 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA

NCT04047849
View directory record Official record
Conditions
Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature, Rupture of Membranes; Premature, Affecting Fetus, Preterm Birth, Preterm PROM (Pregnancy), Preterm Labor
Interventions
Antibiotics, oral Azithromycin and oral Amoxicillin
Drug
Lead sponsor
Woman's
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 26, 2026, 1:12 PM EDT
Completed Phase 4 Interventional Results available

Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial

NCT05322252
View directory record Official record
Conditions
Abortion, Second Trimester, PPROM, Rupture, Spontaneous, Fetal Demise, Fetal Death, Fetal Demise From Miscarriage, Fetal Death Before 22 Weeks With Retention of Dead Fetus, Pregnancy Loss, Pregnancy Complications
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 26, 2026, 1:12 PM EDT
Withdrawn No phase listed Observational

fFN & E3 in the Prediction of PTB in Women With Twin Pregnancies Receiving 17OHP or Placebo

NCT00156000
View directory record Official record
Conditions
Preterm Delivery, Preterm Birth
Interventions
Fetal Fibronectin, Salivary Estriol
Device
Lead sponsor
Obstetrix Medical Group
Industry
Eligibility
18 Years to 60 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Mesa, Arizona • Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 26, 2026, 1:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19

NCT04718220
View directory record Official record
Conditions
Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus, Neonatal Infection, Prenatal Stress, Preterm Birth
Interventions
Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 26, 2026, 1:12 PM EDT
Not listed No phase listed Observational

Preterm Delivery Risk Prediction by Measurement of Prenatal Serum Screening Markers

NCT01009723
View directory record Official record
Conditions
Preterm Delivery
Interventions
Not listed
Lead sponsor
Esoterix Genetic Laboratories, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Westborough, Massachusetts • Santa Fe, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 8, 2012 · Synced Oct 26, 2026, 1:12 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices

NCT03172858
View directory record Official record
Conditions
Premature Rupture of Membrane, Unfavorable Cervix
Interventions
Intracervical balloon catheter, Oxytocin
Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Oct 26, 2026, 1:12 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Indomethacin Versus Placebo in Women With Preterm Premature Rupture of Membranes (PPROM)

NCT00466128
View directory record Official record
Conditions
Preterm Premature Rupture of Membranes
Interventions
indomethacin
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Oct 26, 2026, 1:12 PM EDT
Completed No phase listed Observational

Biomarkers in Obstetrical Complications

NCT03480139
View directory record Official record
Conditions
Pregnancy, Preterm Labor, Maternal Fetal Factors, Preterm Birth
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 45 Years
Enrollment
746 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 26, 2026, 1:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Ripening in Premature Rupture of Membranes

NCT02314728
View directory record Official record
Conditions
Pregnancy, Premature Rupture of Membranes, Preterm Premature Rupture of Membranes, Unfavorable Cervix
Interventions
Misoprostol, Oxytocin
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 26, 2026, 1:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intrapartum Study of Sterile and Clean Gloves

NCT01852188
View directory record Official record
Conditions
Chorioamnionitis
Interventions
Type of glove used for intrapartum vaginal exams
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2018 · Synced Oct 26, 2026, 1:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Euglycemia After Antenatal Late Preterm Steroids, the E-ALPS Study

NCT03076775
View directory record Official record
Conditions
Pregnancy Preterm, Neonatal Hypoglycemia, Hyperglycemia Drug Induced
Interventions
Maternal glycemic control
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Birmingham, Alabama • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 26, 2026, 1:12 PM EDT
Completed Phase 1 Interventional

Pravastatin for Prevention of Preeclampsia

NCT01717586
View directory record Official record
Conditions
Preeclampsia
Interventions
Pravastatin, Placebo
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 26, 2026, 1:12 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Treatment of Chorioamnionitis After Delivery

NCT00814905
View directory record Official record
Conditions
Chorioamnionitis
Interventions
saline, ampicillin gentamicin, ampicillin gentamicin clindamycin
Drug
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 26, 2026, 1:12 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term

NCT05603624
View directory record Official record
Conditions
Chorioamnionitis, Intrauterine Infection, Postpartum Endometritis, Puerperal Infection
Interventions
Cervical examination to assess labor
Procedure
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2023 · Synced Oct 26, 2026, 1:12 PM EDT
Completed No phase listed Observational

Selective Use of Antibiotics in Neonates Born to Mothers With Suspected Chorioamnionitis

NCT03576560
View directory record Official record
Conditions
Chorioamnionitis
Interventions
Retrospective Chart Review
Other
Lead sponsor
Pediatrix
Other
Eligibility
35 Weeks to 42 Weeks · Female only
Enrollment
768 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Oct 26, 2026, 1:12 PM EDT
Recruiting Phase 1 Interventional

Neonatal White Matter Injury Trial (WRAP)

NCT07688746
View directory record Official record
Conditions
White Matter Injury, Brain Injury, Fetus and Neonate, Neonatal Brain Injury, Periventricular Leukomalacia, Periventricular White Matter Abnormalities
Interventions
Clemastine fumarate
Drug
Lead sponsor
Bridget LaMonica Ostrem, M.D., Ph.D.
Other
Eligibility
3 Weeks to 20 Weeks
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 26, 2026, 1:12 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

fFN Clinical Evaluation in Asymptomatic Women at High Risk for Preterm Birth

NCT01955148
View directory record Official record
Conditions
Pre-term Birth
Interventions
Not listed
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
1,210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
16
States / cities
Birmingham, Alabama • San Diego, California • Newark, Delaware + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 26, 2026, 1:12 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

NCT06980025
View directory record Official record
Conditions
Preterm Delivery, Obstetrical Complications
Interventions
162mg Aspirin, 81mg Aspirin
Drug
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
14 Years and older · Female only
Enrollment
1,800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
14
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 26, 2026, 1:12 PM EDT
Withdrawn Phase 2 Interventional

Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure

NCT00598429
View directory record Official record
Conditions
Infant, Newborn, Respiratory Insufficiency, Pulmonary Hypertension, Respiratory Distress Syndrome, Newborn, Streptococcal Infections
Interventions
Inhaled Prostaglandin E1
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 7 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
11
States / cities
Birmingham, Alabama • Palo Alto, California • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 26, 2026, 1:12 PM EDT