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Showing 1–24 of 74 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prematurity of Fetus Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Feasibility of Integrating Maternal Nutrition Interventions Into an Existing MNCH Platform in Bangladesh

NCT02745249
View directory record Official record
Conditions
Poor Fetal Growth, Small-for-gestational Age, Premature Birth
Interventions
Maternal Nutrition Behavior change
Behavioral
Lead sponsor
International Food Policy Research Institute
Other
Eligibility
18 Years to 45 Years
Enrollment
3,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2017 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis

NCT00879190
View directory record Official record
Conditions
Chorioamnionitis
Interventions
Unasyn, Ampicillin/gentamicin
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Sep 10, 2026, 4:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biophysical Profile in Preterm Pregnancies

NCT02561364
View directory record Official record
Conditions
Fetal Development
Interventions
Not listed
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Sep 10, 2026, 4:01 PM EDT
Terminated No phase listed Observational

Clinical Evaluation of the AmniSure ROM Test

NCT01847820
View directory record Official record
Conditions
Rupture of Fetal Membranes
Interventions
AmniSure ROM test
Device
Lead sponsor
QIAGEN Gaithersburg, Inc
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
4
States / cities
Fresno, California • Indianapolis, Indiana • Kansas City, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Sep 10, 2026, 4:01 PM EDT
Active, not recruiting No phase listed Observational

Dilapan-S®: A Multicenter US E-registry

NCT04451109
View directory record Official record
Conditions
Post Term Pregnancy, Premature Rupture of Membrane, Fetal Growth Retardation, Oligohydramnios, Gestational Diabetes, High Blood Pressure in Pregnancy
Interventions
Dilapan-S
Device
Lead sponsor
Medicem Technology s.r.o.
Other
Eligibility
18 Years and older · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 10, 2026, 4:01 PM EDT
Withdrawn Phase 2 Interventional

Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure

NCT00598429
View directory record Official record
Conditions
Infant, Newborn, Respiratory Insufficiency, Pulmonary Hypertension, Respiratory Distress Syndrome, Newborn, Streptococcal Infections
Interventions
Inhaled Prostaglandin E1
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 7 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
11
States / cities
Birmingham, Alabama • Palo Alto, California • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

FOLCROM Trial: Foley Catheter in Rupture of Membranes

NCT01973036
View directory record Official record
Conditions
Premature Rupture of Membranes
Interventions
Foley Catheter, Oxytocin
Device · Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
Female only
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
5
States / cities
Phoenix, Arizona • Newark, Delaware • Allentown, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced Sep 10, 2026, 4:01 PM EDT
Withdrawn No phase listed Observational

fFN & E3 in the Prediction of PTB in Women With Twin Pregnancies Receiving 17OHP or Placebo

NCT00156000
View directory record Official record
Conditions
Preterm Delivery, Preterm Birth
Interventions
Fetal Fibronectin, Salivary Estriol
Device
Lead sponsor
Obstetrix Medical Group
Industry
Eligibility
18 Years to 60 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Mesa, Arizona • Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Sep 10, 2026, 4:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Prediction and Prevention of Preterm Birth (PREVENT-PTB Study)

NCT03530332
View directory record Official record
Conditions
Preterm Birth
Interventions
PreTRM test
Diagnostic Test
Lead sponsor
Ware Branch
Other
Eligibility
18 Years and older · Female only
Enrollment
1,208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
4
States / cities
Murray, Utah • Ogden, Utah • Provo, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2020 · Synced Sep 10, 2026, 4:01 PM EDT
Recruiting Phase 1 Interventional

Neonatal White Matter Injury Trial (WRAP)

NCT07688746
View directory record Official record
Conditions
White Matter Injury, Brain Injury, Fetus and Neonate, Neonatal Brain Injury, Periventricular Leukomalacia, Periventricular White Matter Abnormalities
Interventions
Clemastine fumarate
Drug
Lead sponsor
Bridget LaMonica Ostrem, M.D., Ph.D.
Other
Eligibility
3 Weeks to 20 Weeks
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Comparison of Once Daily Versus 8 Hour Dosing of Gentamicin for the Treatment of Intrapartum Chorioamnionitis

NCT00185991
View directory record Official record
Conditions
Chorioamnionitis
Interventions
gentamicin
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2011 · Synced Sep 10, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional

Physiological and Psychological Effects of Music Therapy in the Pregnant Woman and Fetus

NCT05893485
View directory record Official record
Conditions
Music Therapy, Preterm Premature Rupture of Membrane (PPROM)
Interventions
Music Therapy Intervention
Behavioral
Lead sponsor
Christina Chianis Reed
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 10, 2026, 4:01 PM EDT
Recruiting Phase 4 Interventional

Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)

NCT06396078
View directory record Official record
Conditions
Preterm Premature Rupture of Membrane, Pregnancy, High Risk, Preterm Birth
Interventions
Ceftriaxone 1000 MG, Clarithromycin 500mg, Metronidazole 500 mg, Ampicillin 2 GM Injection, Amoxicillin 250 MG, Azithromycin, Erythromycin
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Columbus, Ohio • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

PROMMO Trial: Oral Misoprostol vs IV Oxytocin

NCT04478942
View directory record Official record
Conditions
Premature Rupture of Membrane, Induction of Labor Affected Fetus / Newborn
Interventions
Misoprostol Oral Product, Intravenous Oxytocin
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19

NCT04718220
View directory record Official record
Conditions
Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus, Neonatal Infection, Prenatal Stress, Preterm Birth
Interventions
Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Phase 2 Interventional Results available

Randomized Trial of Maternal Progesterone Therapy

NCT02133573
View directory record Official record
Conditions
Congenital Heart Disease, Periventricular Leucomalacia, Brain Development, Cardiac Surgery, Neurodevelopmental Disability, Fetal Neuroprotection
Interventions
Progesterone, Vaginal lubricant
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Sep 10, 2026, 4:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term

NCT05603624
View directory record Official record
Conditions
Chorioamnionitis, Intrauterine Infection, Postpartum Endometritis, Puerperal Infection
Interventions
Cervical examination to assess labor
Procedure
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Sep 10, 2026, 4:01 PM EDT
Completed No phase listed Observational

Performance of the Monica Novii Wireless Patch System in Pre-term Labor

NCT03057275
View directory record Official record
Conditions
Premature Labor
Interventions
Abdominal fetal/maternal monitoring
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older · Female only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Supplementation of Fluoride on Maternal Periodontal Health, Preterm Delivery, and Perinatal Well-Being

NCT02536352
View directory record Official record
Conditions
Preterm Birth, Preterm Labor, Bacteremia, Preterm Premature Rupture of Fetal Membranes
Interventions
Prenatal vitamin-mineral containing 3 mg fluoride, Prenatal vitamin-mineral containing 0 mg fluoride
Drug · Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Sep 10, 2026, 4:01 PM EDT
Completed Phase 2Phase 3 Interventional

Dextrose Gel Does Not Prevent Neonatal Hypoglycemia

NCT02523222
View directory record Official record
Conditions
Hypoglycemia, Infant, Small for Gestational Age, Premature Birth of Newborn, Fetal Macrosomia, Intrauterine Growth Restriction, Complication of Prematurity, Neonatal Hypoglycemia
Interventions
40% Dextrose gel
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
0 Hours to 1 Hour
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 10, 2026, 4:01 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

NCT06980025
View directory record Official record
Conditions
Preterm Delivery, Obstetrical Complications
Interventions
162mg Aspirin, 81mg Aspirin
Drug
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
14 Years and older · Female only
Enrollment
1,800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
14
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 10, 2026, 4:01 PM EDT
Completed No phase listed Observational

Selective Use of Antibiotics in Neonates Born to Mothers With Suspected Chorioamnionitis

NCT03576560
View directory record Official record
Conditions
Chorioamnionitis
Interventions
Retrospective Chart Review
Other
Lead sponsor
Pediatrix
Other
Eligibility
35 Weeks to 42 Weeks · Female only
Enrollment
768 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 10, 2026, 4:01 PM EDT
Completed No phase listed Observational

Studying Fetal Breathing Patterns

NCT00066976
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
2
States / cities
San Diego, California • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 10, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fresh RX: NHS 2020

NCT04845230
View directory record Official record
Conditions
Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization, Nutrition Deficiency Due to Insufficient Food, Housing Problems, Fetal Complications, Food Deprivation
Interventions
FreshRx Nourishing Healthy Starts
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 55 Years · Female only
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Sep 10, 2026, 4:01 PM EDT