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Showing 25–40 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prenatal Depression Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)

NCT06979154
View directory record Official record
Conditions
Antenatal Depression, Major Depressive Disorder, Major Depressive Disorder in Pregnancy, Healthy Controls
Interventions
tACS (aperiodic)
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional

How Does Mindful Mood Balance for Moms Work?

NCT05000879
View directory record Official record
Conditions
Depression, Pregnancy Related, Antenatal Depression, Depression, Postpartum
Interventions
MMB for Moms
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Online Prenatal Trial in Mindfulness Sleep Management

NCT04016428
View directory record Official record
Conditions
Pregnancy Related, Insomnia, Depression
Interventions
OPTIMISM, Sleep Education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Intervention for IPV-exposed Pregnant Women

NCT04068662
View directory record Official record
Conditions
Postpartum Depression, Posttraumatic Stress Disorder, Infant Behavior, Violence, Parenting
Interventions
Pregnant Moms' Empowerment Program, Nondirective Support Group
Behavioral
Lead sponsor
University of Notre Dame
Other
Eligibility
3 Months to 55 Years · Female only
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Notre Dame, Indiana • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional

The Stony Brook University Calm-Mom Study

NCT04018625
View directory record Official record
Conditions
Pregnancy Related, Stress, Psychological, Anxiety, Perinatal Depression
Interventions
SMART Mom, Mama Support
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 22, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

NCT06175104
View directory record Official record
Conditions
Heart Defects, Congenital, Anxiety in Pregnancy, Depression, Postpartum, Trauma, Psychological, Neurodevelopmental Disorders
Interventions
HeartGPS
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Jul 22, 2026, 2:15 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression

NCT01732055
View directory record Official record
Conditions
Partner Assisted Interpersonal Psychotherapy, Treatment as Usual
Interventions
Partner-Assisted Interpersonal Psychotherapy, Treatment as Usual
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2014 · Synced Jul 22, 2026, 2:15 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Can Oxytocin Level Predict Postpartum Depression?

NCT02020148
View directory record Official record
Conditions
Postpartum Depression
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Online Yoga With Facebook After Stillbirth

NCT04077476
View directory record Official record
Conditions
Stillbirth, Post-traumatic Stress Disorder, Anxiety, Depression
Interventions
Online Yoga + Facebook, Online Yoga
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Jul 22, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional

In-person vs. Virtual Delivery of a Group-based Prevention of Postpartum Depression

NCT05766475
View directory record Official record
Conditions
Postpartum Depression
Interventions
ROSE Program: In Person, ROSE Program: Virtual
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
18 Years and older · Female only
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mentors Offering Maternal Support (M-O-M-S™): A Prenatal Program for Decreasing Maternal Anxiety and Depression

NCT03393637
View directory record Official record
Conditions
Anxiety Fear, Prenatal Depression, Infant, Low Birth Weight, Preterm Birth, Maternal
Interventions
Mentors Offering Maternal Support (M-O-M-S)
Behavioral
Lead sponsor
University of the Incarnate Word
Other
Eligibility
18 Years and older · Female only
Enrollment
1,717 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
3
States / cities
San Diego, California • San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Integrated Chronotherapy for Perinatal Depression

NCT02053649
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Postpartum Depression
Interventions
Triple Chronotherapy, Usual Care
Behavioral · Other
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional

3D Maternal Fetal Bonding

NCT04540458
View directory record Official record
Conditions
Maternal-Fetal Relations, Paternal Behavior, Maternal Behavior
Interventions
3D printed model, Placebo
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 45 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Group Interpersonal Psychotherapy for Treatment of Major Depressive Disorder Following Perinatal Loss

NCT01867749
View directory record Official record
Conditions
Major Depressive Disorder, Miscarriage, Stillbirth, Neonatal Death
Interventions
Group Interpersonal Psychotherapy (IPT-G), Coping with Depression (CWD)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Jul 22, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prenatal Education About Reducing Labor Stress (PEARLS)

NCT02327559
View directory record Official record
Conditions
Labor Pain, Tocophobia
Interventions
Mind in Labor (MIL): Working with Pain in Childbirth, Treatment as usual (TAU)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 24, 2017 · Synced Jul 22, 2026, 2:15 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The DC Mother-Infant Behavioral Wellness Program

NCT05345834
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety, Prenatal Stress
Interventions
Patient Navigation, Adapted Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jul 22, 2026, 2:15 PM EDT