Independent directory Public ClinicalTrials.gov records United States
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Showing 49–72 of 110 matching trials from the live ClinicalTrials.gov search.
Conditions
Opioid Overdose
Interventions
Enhanced Overdose Education (EOE), Standard education
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Hartford, Connecticut
Conditions
Chronic Pain, Opioid Misuse, Opioid Use Disorder
Interventions
Empowered Relief On-Demand, Health Education
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Results available

THRIVE: Culturally AdapTed Harm Reduction Intervention

NCT06609278
Conditions
Opioid Use, Stimulant Use
Interventions
harm reduction intervention
Behavioral
Lead sponsor
Brittany Miller-Roenigk
Other
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Louisville, Kentucky • Cincinnati, Ohio
Conditions
Pain, Opioid Abuse, Pregnancy
Interventions
CBT for Chronic Pain in Pregnancy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Opioid Rapid Response System: Naloxone Training in Communities

NCT06238128
Conditions
Opioid Overdose
Interventions
Opioid Rapid Resonse System (ORRS) training, Non-active opioid overdose response training
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 100 Years
Enrollment
773 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Access to Naloxone to Prevent Opioid Overdose Deaths (SAIA-Naloxone)

NCT05886712
Conditions
Overdose, Implementation as Usual
Interventions
Naloxone, Usual intervention
Other
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Berkeley, California
Conditions
Opioid Overdose
Interventions
RELAY
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Safety & Prevention Outcomes Study

NCT01894087
Conditions
Drug Overdose, Opioid-Related Disorders
Interventions
TBI - Cohort 1, TBI - Cohort 2
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Active, not recruiting Not applicable Interventional

Healthy Opioid Prescription Engagement

NCT05141266
Conditions
Opioid Misuse, Opioid-Related Disorders, Pharmacist-Patient Relations
Interventions
Patient Navigation, Standard Medication Counseling (SMC)
Behavioral · Other
Lead sponsor
Jerry Cochran
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

NCT05657106
Conditions
Opioid-Related Disorders, Hepatitis C (HCV), Human Immunodeficiency Virus (HIV), Drug Overdose, Substance Abuse, Intravenous Drug Usage, Opiate Substitution Treatment, Sexually Transmitted Diseases
Interventions
Health kiosk
Behavioral
Lead sponsor
April M Young
Other
Eligibility
18 Years and older
Enrollment
752 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Recruiting Not applicable Interventional Accepts healthy volunteers

UnityPhilly Response App for Overdose Reversal

NCT06466005
Conditions
Opioid Overdose
Interventions
UnityPhilly app
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

iSTART: A Campus & Community Initiative for Services in Tec-health

NCT05362357
Conditions
Substance Use, Binge Drinking, Marijuana Use, Alcohol Drinking, Prescription Opioid Misuse, Illicit Drug Use
Interventions
iSTART Web-app
Behavioral
Lead sponsor
California State University, Northridge
Other
Eligibility
18 Years to 30 Years
Enrollment
1,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Northridge, California
Completed Not applicable Interventional Results available

SafetyNet Program for Opioid Use Disorder (OUD)

NCT04253782
Conditions
Opioid-Use Disorder (OUD)
Interventions
Team Intervention
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 130 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
New Haven, Connecticut
Withdrawn Not applicable Interventional Accepts healthy volunteers

Tailoring Overdose Education for Black Churches

NCT05645016
Conditions
Opioid Overdose
Interventions
COEST
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Chronic Pain, Prescription Opioid Misuse, Substance-Related Disorders, Pain, Narcotic-Related Disorders, Chemically-Induced Disorders, Mental Disorders, Opioid-Related Disorders, Neurologic Manifestations
Interventions
Mindfulness Oriented Recovery Enhancement, Patient-Centered Chronic Pain Management Visits
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
La Jolla, California • New Brunswick, New Jersey • Salt Lake City, Utah
Completed Not applicable Interventional Results available

Repeated-dose Behavioral Intervention to Reduce Opioid Overdose

NCT03838510
Conditions
Opioid-Related Disorders, Drug Overdose
Interventions
REBOOT
Behavioral
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
18 Years to 65 Years
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Completed No phase listed Observational

Kentucky Access to Recovery Evaluation

NCT05889702
Conditions
Substance Use Disorders, Treatment Adherence and Compliance
Interventions
KATR Linkage Strategy
Behavioral
Lead sponsor
Terry Bunn
Other
Eligibility
18 Years and older
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Berea, Kentucky • Lexington, Kentucky
Conditions
Opioid-Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
Interventions
Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)
Other
Lead sponsor
Member Companies of the Opioid PMR Consortium
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Overdose, Risk Behavior
Interventions
Co-Dispensing
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Opioid Overdose
Interventions
Educational Webinar, Resources, Reminders
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Auburn, Alabama
Completed No phase listed Observational Results available

User Acceptability of a Device-Based Opioid Overdose Intervention

NCT04530591
Conditions
Opioid Overdose, Opioid-use Disorder, Substance Use Disorders
Interventions
Survey, Interview
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Terminated Phase 4 Interventional Results available

Conversion to Embeda With Rescue Trial

NCT01179191
Conditions
Chronic Disease, Pain
Interventions
morphine sulfate and naltrexone hydrochloride (EMBEDA)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
21 Years and older
Enrollment
684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
166
States / cities
Adamsville, Alabama • Birmingham, Alabama • Huntsville, Alabama + 144 more
Completed Not applicable Interventional Results available

Primary Care Intervention to Reduce Prescription Opioid Overdoses

NCT02464410
Conditions
Pain, Drug Overdose, Opioid Use Disorders
Interventions
Motivational intervention, Psycho-educational control, Long-term opioid therapy informed consent
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Recruiting Phase 1Phase 2 Interventional

A Bundled Intervention

NCT06593093
Conditions
Opioid Use Disorder, Opioid Overdose
Interventions
a bundled intervention, control group
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama