Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Jun 26, 2026, 7:05 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Opioid Abuse, Overdose, Risk Behavior
Interventions
Naloxone Navigator 1.0
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

Opioid Rapid Response System: Naloxone Training in Communities

NCT06238128
Conditions
Opioid Overdose
Interventions
Opioid Rapid Resonse System (ORRS) training, Non-active opioid overdose response training
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 100 Years
Enrollment
773 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Withdrawn No phase listed Observational Accepts healthy volunteers

DESIGNING A PROGRAMMING LANGUAGE FOR PATIENT-ORIENTED PRESCRIPTIONS (POP-PL)

NCT03837418
Conditions
Programming Languages, Patients
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
0 Years to 79 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Completed No phase listed Observational Results available

Parental Perceptions on Prescription Opioid Use

NCT05344118
Conditions
Orthopedic Disorder
Interventions
Survey
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Completed Phase 4 Interventional Accepts healthy volunteers

The DEPOT Study (Dry Eye Prescription Options for Therapy)

NCT04911361
Conditions
Dry Eye
Interventions
Dexamethasone
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
3
States / cities
Hemet, California • Laguna Hills, California • St Louis, Missouri
Completed Phase 3 Interventional Accepts healthy volunteers

Exercise and Physical Fitness for Persons With Knee Osteoarthritis

NCT00265447
Conditions
Knee Osteoarthritis
Interventions
Strength training, Aerobic conditioning, Delayed exercise
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
50 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Opioid Use Disorder, Bereavement, Overdose of Opiate
Interventions
Survey
Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
578 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Sexually Active
Interventions
Text Message
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional

Eat Well Heart Failure

NCT07101289
Conditions
Congestive Heart Failure Chronic
Interventions
Personal health planning and nutritional coaching, Prescription Produce
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Pain, Abuse, Drug
Interventions
Oxycodone, Cannabis (THC:CBD = ~ 1:0), Cannabis (THC:CBD = ~ 0:1), Cannabis (THC:CBD = ~ 1:1), Placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 53 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Safety & Prevention Outcomes Study

NCT01894087
Conditions
Drug Overdose, Opioid-Related Disorders
Interventions
TBI - Cohort 1, TBI - Cohort 2
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Type 2 Diabetes
Interventions
Fruit and Vegetable Prescription Voucher
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
Up to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Shared Decision Making for Prescription Opioids After Cesarean Delivery

NCT02770612
Conditions
Pregnancy, Cesarean Section, Prescriptions, Analgesics, Opioid
Interventions
Prescribed opioids
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational

Kentucky Access to Recovery Evaluation

NCT05889702
Conditions
Substance Use Disorders, Treatment Adherence and Compliance
Interventions
KATR Linkage Strategy
Behavioral
Lead sponsor
Terry Bunn
Other
Eligibility
18 Years and older
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Berea, Kentucky • Lexington, Kentucky
Conditions
Modality of Discharge Instructions
Interventions
Text Message, Voicemail
Other
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
Not listed
Enrollment
2,874 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Otitis Media
Interventions
Prescription Fill Status
Behavioral
Lead sponsor
Yale University
Other
Eligibility
6 Months to 12 Years
Enrollment
240 participants
Timeline
2004 – 2005
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Phase 2Phase 3 Interventional Results available

Improving Treatment Outcomes for Prescription Opioid Dependence

NCT02543944
Conditions
Drug Dependence
Interventions
Gabapentin, Buprenorphine, Clonidine, Naltrexone (oral), Naltrexone (depot), Placebo
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 65 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Alzheimer's Disease
Interventions
Activity matched to interest, Activity matched to function, Activity matched to both interest and function
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
65 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
University Park, Pennsylvania
Completed Phase 2 Interventional

Fitness After Stroke Trial

NCT05936008
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic
Interventions
Exercise MICT, Exercise HIIT
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
20 Years to 85 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Opiate Overdose, Opioid-Related Disorders, Narcotic-Related Disorders, Substance-related Disorders, Chemically-Induced Disorders, Mental Disorders
Interventions
Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
674 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Acetaminophen, Drug Overdose, Acetaminophen Overdose, Acetaminophen Poisoning, Drug-induced Liver Injury, Liver Failure, Liver Toxicity
Interventions
Intravenous infusion of N-acetylcysteine, Intravenous infusion of Fomepizole (4-MP)
Drug
Lead sponsor
Richard Dart, MD, PhD
Other
Eligibility
10 Years to 99 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Denver, Colorado
Completed Not applicable Interventional Results available

Peer Intervention to Link Overdose Survivors to Treatment (PILOT)

NCT05123027
Conditions
Opioid Overdose
Interventions
Peer Intervention to Link Overdose Survivors to Treatment (PILOT) Peer, Treatment As Usual Peer
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Youngstown, Ohio • Greenville, South Carolina • Everett, Washington
Conditions
Overdose, Opioid-related Disorders, Drug Addiction, Drug Abuse, Substance Abuse, Opioid Use, Unspecified, Opioid Dependence, Drug Overdose
Interventions
TTIP-PRO
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Cincinnati, Ohio
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition

NCT06651528
Conditions
Substance Use Disorder (SUD)
Interventions
TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
Michele Staton
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
4
States / cities
Frankfort, Kentucky • Pewee Valley, Kentucky • Chillicothe, Missouri + 1 more