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ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:17 PM EDT

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Showing 121–144 of 179 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pressure Ulcer Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Gamified Learning for Pressure Injury Prevention

NCT07028892
View directory record Official record
Conditions
Pressure Injuries, Pressure Ulcer Prevention
Interventions
A gamified mobile learning, Booklet training
Device · Other
Lead sponsor
Mehmet Akif Ersoy University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 21, 2026, 3:17 PM EDT
Terminated Phase 4 Interventional Results available

Study of SANTYL® vs Hydrogel (SoloSite®) for Pressure Ulcers

NCT02718625
View directory record Official record
Conditions
Pressure Ulcer
Interventions
Santyl, SoloSite®
Biological
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lee's Summit, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 21, 2026, 3:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries

NCT05496296
View directory record Official record
Conditions
Pressure Ulcers Stage II, Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
Interventions
Altrazeal® Transforming Powder Dressing
Device
Lead sponsor
ULURU Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
14
States / cities
San Diego, California • Washington D.C., District of Columbia • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional Results available

Enhancing Diabetic Foot Education by Viewing Personal Plantar Pressures

NCT01941719
View directory record Official record
Conditions
Diabetes Mellitus, Diabetic Neuropathies, Foot Complications
Interventions
Enhanced foot care education, Standard Foot Care Education
Behavioral
Lead sponsor
Temple University
Other
Eligibility
21 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Oct 21, 2026, 3:17 PM EDT
Withdrawn Not applicable Interventional

Negative Pressure Wound Therapy as a Drug Delivery System (ADANPWT)

NCT02308800
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
Quantum™ Therapy - NPWT with Prontosan, Quantum™ Therapy
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Oct 21, 2026, 3:17 PM EDT
Recruiting Not applicable Interventional

Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

NCT06529094
View directory record Official record
Conditions
Spinal Cord Injury, Pressure Injury
Interventions
Provider training, CAPP-FIT intervention with RA facilitation, CAPP-FIT implementation during maintenance phase
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
808 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
8
States / cities
Long Beach, California • Palo Alto, California • Tampa, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

How Shoes With Rocker Soles Affect Walking

NCT00006438
View directory record Official record
Conditions
Diabetic Feet
Interventions
Shoes with Rocker Soles
Device
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
40 Years to 60 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 1999
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional Results available

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

NCT04989790
View directory record Official record
Conditions
Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
Interventions
PICU Up!
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Not listed
Enrollment
1,470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
11
States / cities
Madera, California • Orlando, Florida • Louisville, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 21, 2026, 3:17 PM EDT
Completed No phase listed Observational

Prospective PuraPly™ AM Case Series Study

NCT03070925
View directory record Official record
Conditions
Pressure Ulcers, Venous Ulcers, Diabetic Ulcers, Surgical Wounds, Trauma Wounds
Interventions
PuraPly™ Antimicrobial Wound Matrix
Device
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 21, 2026, 3:17 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Analysis of Skin Temperature by Long Wave Infrared Imaging to Determine Its Effectiveness as a Predictor of Tissue Injury

NCT00664235
View directory record Official record
Conditions
Pressure Ulcers, Tissue Injury
Interventions
Not listed
Lead sponsor
Trillennium Medical Imaging, Inc.
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2008 · Synced Oct 21, 2026, 3:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study

NCT00759889
View directory record Official record
Conditions
Diabetic Foot, Leg Ulcer, Decubitus Ulcer
Interventions
Not listed
Lead sponsor
Southwest Regional Wound Care Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2018
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional Results available

Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPWT)

NCT02470806
View directory record Official record
Conditions
Venous Leg Ulcers, Diabetic Foot Ulcers
Interventions
PICO System, tNPWT System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
15
States / cities
Carlsbad, California • Fresno, California • Martinez, California + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 21, 2026, 3:17 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Wound Care and Pressure Injury Through the Continuum of Care

NCT04649853
View directory record Official record
Conditions
Wound, Pressure Injury
Interventions
Standardized nursing care
Other
Lead sponsor
Regional Medical Center of San Jose
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Oct 21, 2026, 3:17 PM EDT
Terminated Phase 1 Interventional

Effect of an Oral Supplement Enriched in Amino Acids and the Leucine Metabolite B-hydroxy B-methylbutyrate (HMB)

NCT00502372
View directory record Official record
Conditions
Pressure Ulcers
Interventions
Nutritional Supplement/Amino acids and HMB, Juven
Dietary Supplement
Lead sponsor
Central Arkansas Veterans Healthcare System
Federal
Eligibility
21 Years to 90 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Phase 4 Interventional Results available

Decreasing Intraoperative Skin Damage in Prone Position Surgeries

NCT04884737
View directory record Official record
Conditions
Pressure Injury
Interventions
Mepilex Border Flex® (MBF) dressing
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Oct 21, 2026, 3:17 PM EDT
Terminated Not applicable Interventional

Coupling Negative Pressure Wound Therapy With Instillation

NCT04677166
View directory record Official record
Conditions
Wound, Ulcer, Burns
Interventions
Negative pressure wound therapy coupled with instillation, Standard Negative Pressure Wound Therapy
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 21, 2026, 3:17 PM EDT
Enrolling by invitation Phase 1 Interventional

Adipose-Derived Stromal Cells (ASC's) for Pressure Ulcers

NCT02375802
View directory record Official record
Conditions
Pressure Ulcer
Interventions
Adipose-derived stromal cells, Adipose-derived stromal cells
Biological · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 21, 2026, 3:17 PM EDT
Active, not recruiting No phase listed Observational

Real-World Effectiveness of Amniotic Membrane Allografts Versus Standard Wound Care in DFU, VLU, and PU

NCT07223281
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs), Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions
Not listed
Lead sponsor
Legacy Medical Consultants
Industry
Eligibility
18 Years and older
Enrollment
2,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
4
States / cities
Colorado Springs, Colorado • Clinton Township, Michigan • Tulsa, Oklahoma + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the SEM Scanner 200 for the Detection of Early Pressure Ulcers: A Multi-Site Longitudinal Study

NCT02701101
View directory record Official record
Conditions
Pressure Ulcers
Interventions
Use of SEM200 Scanner daily, Assessment and treatment of Pressure Ulcers using SOC
Device · Other
Lead sponsor
Bruin Biometrics, LLC
Industry
Eligibility
55 Years and older
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional

MicroMatrix® Flex in Tunneling Wounds

NCT06629506
View directory record Official record
Conditions
Pressure Injury, Venous Ulcer, Necrotizing Soft Tissue Infection, Diabetic Ulcers, Draining Wound
Interventions
MicroMatrix® Flex, MicroMatrix® UBM Particulate, Cytal® Wound Matrix 2-Layer
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
22 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Aurora, Colorado • Washington D.C., District of Columbia • Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Phase 4 Interventional Results available

Wound Management for Sacral Pressure Ulcers With Necrotic Tissue

NCT02224638
View directory record Official record
Conditions
Pressure Ulcers
Interventions
TheraHoney HD, SkinTegrity
Device
Lead sponsor
Medline Industries
Industry
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional

Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.

NCT04776967
View directory record Official record
Conditions
Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury, Pressure Injury, Ear Barotrauma
Interventions
Hyperbaric Compression Profile
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional Results available

Effect of HPIPC for the Treatment of Ischemic Ulcers in Subjects With PAD

NCT01420289
View directory record Official record
Conditions
PVD, Arterial Ulcers
Interventions
High pressure intermittent pneumatic compression (HPIPC), Excercise
Device · Behavioral
Lead sponsor
Calvary Hospital, Bronx, NY
Other
Eligibility
18 Years to 90 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2012 · Synced Oct 21, 2026, 3:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pressure Alternating Shoes

NCT06026813
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
test pressure alternating shoes
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 21, 2026, 3:17 PM EDT