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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Preterm Birth Complication Clear all
Completed Not applicable Interventional

Nifedipine vs Placebo for Maintenance Tocolysis of Preterm Labor.

NCT00185952
View directory record Official record
Conditions
Obstetric Labor, Premature, Venous Thrombosis
Interventions
Nifedipine
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2011 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Phase 2Phase 3 Interventional

Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome

NCT01203358
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Bronchopulmonary Dysplasia
Interventions
Exosurf, Survanta
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 6 Hours
Enrollment
617 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 1992
U.S. locations
13
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Jul 21, 2026, 11:53 AM EDT
Terminated Not applicable Interventional

Maternal Voice and Quantitative EEG (qEEG)

NCT05391633
View directory record Official record
Conditions
Prematurity, Development Delay, Premature Birth
Interventions
Recorded Maternal Voice, Placebo Recording
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
28 Weeks to 33 Weeks
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Jul 21, 2026, 11:53 AM EDT
Recruiting Not applicable Interventional

Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey

NCT06822647
View directory record Official record
Conditions
Cervical Insufficiency, Preterm Birth, Cervical Length Measurement
Interventions
Cervical Length Measurement at the Beginning of the Anatomy Survey, Cervical Length Measurement at the End of the Anatomy Survey
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
Female only
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jul 21, 2026, 11:53 AM EDT
Withdrawn Phase 1 Interventional

Pilot Study of Electronic Uterine Contraction Inhibitor

NCT00994058
View directory record Official record
Conditions
Prematurity
Interventions
Electrical Inhibition (EI) Uterine Pacemaker
Device
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Jul 21, 2026, 11:53 AM EDT
No Longer Available No phase listed Expanded access

Aerosolized Infasurf Treatment Protocol: Aerosolized Infasurf for Spontaneously Breathing Patients With Early RDS (AERO-03)

NCT03582930
View directory record Official record
Conditions
Neonatal Respiratory Distress
Interventions
Infasurf Aero
Combination Product
Lead sponsor
ONY
Industry
Eligibility
Up to 42 Weeks
U.S. locations
5
States / cities
Jackson, Mississippi • Buffalo, New York • Greenville, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Two Methods of Diagnosing Preterm Labor

NCT01431885
View directory record Official record
Conditions
Preterm Labor, Preterm Delivery
Interventions
Diagnosis by cervical length and fibronectin, Cervical change
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Not applicable Interventional

Educational/Behavioral Intervention Program for Parents of Premature Infants

NCT00120614
View directory record Official record
Conditions
Premature Birth
Interventions
Premature infant behavior and development information, Parental activities to support premature infant information
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
260 participants
Timeline
2001 – 2007
U.S. locations
2
States / cities
Rochester, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2009 · Synced Jul 21, 2026, 11:53 AM EDT
Not listed No phase listed Observational

Non-invasive Test to Detect Intra-amniotic Infection in Women With Preterm Labor and Intact Amniotic Membranes

NCT00700219
View directory record Official record
Conditions
Intra-amniotic Infection
Interventions
Not listed
Lead sponsor
ProteoGenix, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
21
States / cities
Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2010 · Synced Jul 21, 2026, 11:53 AM EDT
Terminated Not applicable Interventional

The Impact of Implementing NIDCAP on Preterm Infants in the NICU

NCT00179933
View directory record Official record
Conditions
Infant, Premature
Interventions
Newborn Individualized Assessment Program
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Jul 21, 2026, 11:53 AM EDT
Completed No phase listed Observational

Cerebral Function Monitoring in Premature Infants

NCT00873847
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Electroencephalography
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 72 Hours
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
8
States / cities
Palo Alto, California • Atlanta, Georgia • Detroit, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2017 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Not applicable Interventional

The Effectiveness of Silver Alginate (Algidex) Patch in the Prevention of Central Line Infections in Very Low Birth Weight Infants

NCT00964093
View directory record Official record
Conditions
Central Line Bloodstream Infections
Interventions
Silver Alginate
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
1 Day to 3 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tobacco Use in Pregnancy Intervention for Cessation

NCT03442530
View directory record Official record
Conditions
Pregnancy
Interventions
ToPIC, Tobacco Treatment As Usual (TTAU)
Behavioral
Lead sponsor
Kristin Ashford
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Brain Development in Medically Healthy Premature Infants

NCT00065364
View directory record Official record
Conditions
Premature Birth
Interventions
Newborn Individualized Developmental Care Assessment Program
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
28 Weeks to 33 Weeks
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2000
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 21, 2026, 11:53 AM EDT
Enrolling by invitation No phase listed Observational

Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

NCT06823115
View directory record Official record
Conditions
Acute Kidney Injury, Fluid Overload, Prematurity Complications, Risk Factors, Epidemiology, Chronic Kidney Disease(CKD), Hypertension
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
0 Minutes to 2 Weeks
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
50
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Palo Alto, California + 45 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jul 21, 2026, 11:53 AM EDT
Completed No phase listed Observational

Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity

NCT01780155
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Retinopathy of Prematurity, Prematurity, Pulmonary Disease
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
Not listed
Enrollment
1,068 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Jul 21, 2026, 11:53 AM EDT
Completed No phase listed Observational

Assessment of the Pulmonary Diffusion Capacity in Healthy Infants and Infants With Chronic Lung Disease

NCT00428038
View directory record Official record
Conditions
Infant, Premature, Bronchopulmonary Dysplasia, Asthma
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
2 Months to 2 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 29, 2012 · Synced Jul 21, 2026, 11:53 AM EDT
Not listed Not applicable Interventional

Vitamin A Supplementation in Preterm Infants

NCT00063596
View directory record Official record
Conditions
Infant, Premature
Interventions
Vitamin A supplementation
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
1 Day to 3 Days
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 21, 2026, 11:53 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor

NCT00306462
View directory record Official record
Conditions
Premature Birth, Premature Labor
Interventions
Magnesium sulfate, Oral Nifedipine or placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 8, 2009 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Not applicable Interventional

Supporting All Families of Premature Infants At Prentice Women's Hospital from Admission Through Discharge

NCT03505424
View directory record Official record
Conditions
Premature Infant, Premature Birth, NICU
Interventions
Group 1: Standard of Care, Group 2: NICU2HOME app, Group 3: SMART NICU2HOME app
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Phase 4 Interventional Results available

Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial

NCT05322252
View directory record Official record
Conditions
Abortion, Second Trimester, PPROM, Rupture, Spontaneous, Fetal Demise, Fetal Death, Fetal Demise From Miscarriage, Fetal Death Before 22 Weeks With Retention of Dead Fetus, Pregnancy Loss, Pregnancy Complications
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Not applicable Interventional

Enhanced Nutrition for Preterm Infants

NCT03238768
View directory record Official record
Conditions
Preterm Birth
Interventions
Enhanced Intravenous Nutrition, Standard Intravenous Nutrition
Other
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 30 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Jul 21, 2026, 11:53 AM EDT
Completed No phase listed Observational

Precision Medicine for Preterm Birth

NCT02173210
View directory record Official record
Conditions
Premature Birth
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
Female only
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Jul 21, 2026, 11:53 AM EDT
Completed Phase 3 Interventional

Dose Comparison of Amino Acids on Growth in Premature Neonates

NCT00120926
View directory record Official record
Conditions
Malnutrition
Interventions
Parenteral Nutrition
Drug
Lead sponsor
Pediatrix
Other
Eligibility
0 Years to 48 Hours
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Florence, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2006 · Synced Jul 21, 2026, 11:53 AM EDT