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ClinicalTrials.gov public records Last synced Oct 25, 2026, 7:53 AM EDT

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Showing 361–384 of 851 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Preterm Infants Clear all
Completed Phase 1Phase 2 Interventional

Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial

NCT01242462
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Conventional Pressure Controlled SIMV, Mid-frequency Ventilation
Procedure · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Hour to 7 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 25, 2026, 7:53 AM EDT
Recruiting No phase listed Observational

Motor-voice Assessment in Infants (MAMI)

NCT06807203
View directory record Official record
Conditions
Cerebral Palsy Infantile, Pre-Term, Motor Delay, Neurodevelopmental Disorders, Autism Spectrum Disorder
Interventions
Behavioral observation
Other
Lead sponsor
Ohio State University
Other
Eligibility
Up to 10 Days
Enrollment
46 participants
Timeline
2025 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 25, 2026, 7:53 AM EDT
Not listed Not applicable Interventional

Evaluating Pressures During Non-invasive Ventilation Utilizing NIV Plus Software

NCT05961683
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn, Apnea of Newborn
Interventions
NIV plus software
Device
Lead sponsor
Keck School of Medicine of USC
Other
Eligibility
0 Days to 30 Days
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 25, 2026, 7:53 AM EDT
Completed No phase listed Observational

Impact of Steroid, Diuretic, and Fluid Use on BPD Outcomes

NCT04971694
View directory record Official record
Conditions
BPD - Bronchopulmonary Dysplasia
Interventions
No interventions or procedures
Other
Lead sponsor
Pediatrix
Other
Eligibility
Not listed
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 25, 2026, 7:53 AM EDT
Not listed Not applicable Interventional

Effects of Mother's Voice and Heartbeat Sounds on Preterm Newborns

NCT01913288
View directory record Official record
Conditions
Preterm Birth
Interventions
Biological Maternal Sounds
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
24 Weeks to 34 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Oct 25, 2026, 7:53 AM EDT
Not listed Not applicable Interventional

Growth and Nutritional Status of Very Low Birth Weight Infants Fed a High Protein Exclusive Human Milk Diet

NCT03839173
View directory record Official record
Conditions
Premature Infant, Breast Milk Expression
Interventions
Human milk based human milk fortifier
Other
Lead sponsor
Augusta University
Other
Eligibility
23 Weeks to 33 Weeks
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Oct 25, 2026, 7:53 AM EDT
Terminated Not applicable Interventional Results available

Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants

NCT03558737
View directory record Official record
Conditions
Infant,Premature, Respiratory Failure, Respiratory Insufficiency, Respiratory Distress Syndrome in Premature Infant
Interventions
Nasal high-frequency jet ventilation (nHFJV), Nasal intermittent positive pressure ventilation (NIPPV)
Other
Lead sponsor
University of Utah
Other
Eligibility
Up to 72 Hours
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 25, 2026, 7:53 AM EDT
Recruiting Not applicable Interventional

Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial

NCT06420531
View directory record Official record
Conditions
Prematurity
Interventions
Human milk
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
6 Hours to 4 Days
Enrollment
486 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
4
States / cities
Birmingham, Alabama • Jackson, Mississippi • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Exclusive Enteral Nutrition in Preterm Neonates

NCT04337710
View directory record Official record
Conditions
Premature; Infant, Light-for-dates, Enteral Feeding Intolerance
Interventions
Exclusive Enteral Nutrition, Progressive Enteral Nutrition
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Hour to 48 Hours
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Aerosolized Surfactant in Neonatal RDS

NCT02294630
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Surfactant
Drug
Lead sponsor
Sood, Beena G., MD, MS
Individual
Eligibility
Up to 24 Hours
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Not applicable Interventional

DTaP and Apnea/Bradycardia in Preterm Infants

NCT00482781
View directory record Official record
Conditions
Prolonged Apnea, Prolonged Bradycardia
Interventions
Infanrix, Pediatrix
Biological
Lead sponsor
American SIDS Institute
Other
Eligibility
56 Days to 60 Days
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
10
States / cities
Austell, Georgia • Marietta, Georgia • Belle Mead, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2007 · Synced Oct 25, 2026, 7:53 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Invictus Medical, Medical Cranial Support Device (CSD) is a Device Safety Study in Infants at Risk of Head Ulcers.

NCT02224859
View directory record Official record
Conditions
Other Preterm Infants
Interventions
HCP will place the Invictus Cranial Support Device (CSD) on the patient, human intervention
Device · Other
Lead sponsor
Invictus Medical, Inc.
Industry
Eligibility
30 Weeks to 36 Weeks
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2015 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Phase 4 Interventional

Premedication for Less Invasive Surfactant Administration Study (PRELISA)

NCT05065424
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
IV Atropine and Fentanyl Premedication Arm, IV Normal Saline Placebo Arm
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
0 Hours to 72 Hours
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 25, 2026, 7:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Sepsis in Ex-Preterm Infants

NCT03433846
View directory record Official record
Conditions
Sepsis, Premature Birth
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Days to 2 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2022 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Iron Status and Myelination in Premature Infants

NCT00684697
View directory record Official record
Conditions
Neurodevelopmental Outcome
Interventions
iron
Dietary Supplement
Lead sponsor
University of Rochester
Other
Eligibility
Up to 32 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 25, 2026, 7:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Human Milk Fortifier and Cytokine Profile

NCT00601081
View directory record Official record
Conditions
Infant, Very Low Birth Weight
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
Up to 6 Months
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 25, 2026, 7:53 AM EDT
Withdrawn Phase 3 Interventional

Thyroxine Treatment in Premature Infants With Intraventricular Hemorrhage

NCT03390530
View directory record Official record
Conditions
Intraventricular Hemorrhage of Prematurity
Interventions
Thyroxine, Placebo
Drug
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
3 Days to 6 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 25, 2026, 7:53 AM EDT
Not yet recruiting No phase listed Observational

Wearable Sensor Toolkit for Infant Motor Development

NCT07866495
View directory record Official record
Conditions
Motor Delay, Infant Development, Motor Development of Premature Infants, Motor Coordination or Function; Developmental Disorder
Interventions
Not listed
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
0 Days to 52 Weeks
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Identifying Vitamin D Deficiency in Very Low Birth Weight Infant (VLBW) Infants Part 2

NCT01363167
View directory record Official record
Conditions
Infant, Very Low Birth Weight, Calcium Deficiency, Vitamin D Deficiency
Interventions
400 IU Cholecalciferol- Vitamin D Daily
Dietary Supplement
Lead sponsor
Medical University of South Carolina
Other
Eligibility
1 Day to 3 Days
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2014 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Electrogastrography (EGC) in Premature Infants With Feeding Intolerance

NCT00008736
View directory record Official record
Conditions
Infant, Newborn, Diseases
Interventions
metoclopramide
Drug
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
1 Minute to 1 Month
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 25, 2026, 7:53 AM EDT
Terminated Phase 4 Interventional Results available

Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome

NCT02164734
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Endotracheal intubation, Laryngeal mask airway, remifentanil
Device · Drug
Lead sponsor
Albany Medical College
Other
Eligibility
2 Hours to 48 Hours
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 25, 2026, 7:53 AM EDT
Recruiting Not applicable Interventional

Multisensory Early Oral Administration of Human Milk (M-MILK) for Very Preterm Infants

NCT07216664
View directory record Official record
Conditions
Infant, Premature, Diseases
Interventions
Multisensory early oral administration of human milk
Other
Lead sponsor
Loyola University
Other
Eligibility
23 Weeks to 32 Weeks
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
2
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Phase 2 Interventional Results available

Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD)

NCT02527798
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Furosemide Cohort 1, Furosemide Cohort 2, Furosemide Cohort 3, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Days to 28 Days
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
21
States / cities
Little Rock, Arkansas • Loma Linda, California • Jacksonville, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Oct 25, 2026, 7:53 AM EDT
Completed Phase 2 Interventional Results available

Improving Right Ventricular Function in Young Adults Born Preterm

NCT03696758
View directory record Official record
Conditions
Infant,Premature
Interventions
Pulmonary Function Testing, Electrocardiogram, Cardiac Magnetic Resonance Imaging, Metoprolol, Sildenafil
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 25, 2026, 7:53 AM EDT