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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:12 AM EDT

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Showing 673–696 of 853 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Preterm Infants Clear all
Recruiting Not applicable Interventional

Multisensory Early Oral Administration of Human Milk (M-MILK) for Very Preterm Infants

NCT07216664
View directory record Official record
Conditions
Infant, Premature, Diseases
Interventions
Multisensory early oral administration of human milk
Other
Lead sponsor
Loyola University
Other
Eligibility
23 Weeks to 32 Weeks
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
2
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 27, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional

Does Starting Feeds on the First Day of Life Help Premature Infants Reach Full Volume Feeds Sooner?

NCT06731439
View directory record Official record
Conditions
Extra Uterine Growth Restriction, Premature Infant Disease, VLBW - Very Low Birth Weight Infant
Interventions
Starting feeds within 6 hours of life, Standard feeding protocol
Other
Lead sponsor
University of Tennessee
Other
Eligibility
1 Minute to 6 Hours
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Phase 2 Interventional Results available

Trial of Intravenous Azithromycin to Eradicate Ureaplasma Respiratory Tract Infection in Preterm Infants

NCT01778634
View directory record Official record
Conditions
Ureaplasma Infections
Interventions
Azithromycin, Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
2 Hours to 72 Hours
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
7
States / cities
Birmingham, Alabama • Newark, Delaware • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2020 · Synced Oct 27, 2026, 1:12 AM EDT
Recruiting No phase listed Observational

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

NCT05347238
View directory record Official record
Conditions
Late-Onset Neonatal Sepsis, Extreme Prematurity, Neonatal Hypotension
Interventions
Dopamine, Norepinephrine
Drug
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
21 Weeks to 32 Weeks
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Phoenix, Arizona • Dayton, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Not applicable Interventional Results available

Monitoring Neonatal Resuscitation Trial

NCT03256578
View directory record Official record
Conditions
Resuscitation, Neonatal Prematurity, Positive-Pressure Respiration
Interventions
New Life Box Respiratory Function Monitor
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
24 Weeks to 28 Weeks
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NICU Asthma Education and Secondhand Smoke Reduction Study

NCT00499915
View directory record Official record
Conditions
Respiratory Illness
Interventions
Secondhand Smoke Reduction and Smoking Cessation Counseling, Asthma Education
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
Not listed
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2015 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Not applicable Interventional Results available

Effect of Colostrum on Mucosal Immunity in Very Low Birth Weight (VLBWs) Premature Infants

NCT01776268
View directory record Official record
Conditions
Prematurity
Interventions
Oral priming
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 1 Year
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 27, 2026, 1:12 AM EDT
Completed No phase listed Observational

Oxygenation Instability and Maturation of Control of Breathing in Premature Infants

NCT03445689
View directory record Official record
Conditions
Infant,Premature
Interventions
Assessment of oxygenation instability, Determination of mechanisms of hypoxemia episodes, Assessment of respiratory instability, apneic threshold of CO2, Assessment of peripheral chemoreceptor function, Assessment of central chemo-receptor function
Other
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Not applicable Interventional

Human Milk Fortification in Very Low Birth Neonates

NCT01988792
View directory record Official record
Conditions
Premature; Infant, Enteral Nutrition, Human Milk, Fortification
Interventions
Human milk fortifiers
Dietary Supplement
Lead sponsor
University of Tennessee
Other
Eligibility
2 Days to 7 Days
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 29, 2015 · Synced Oct 27, 2026, 1:12 AM EDT
Recruiting No phase listed Observational

Optimizing Nutrition and Milk (Opti-NuM) Project

NCT06870981
View directory record Official record
Conditions
Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant, Nutritional Requirements, Human Milk Fortification, Human Milk Microbiome, Human Milk Feeding, Human Milk Nutrition, Growth &Amp; Development
Interventions
Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.
Other
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
1 Hour to 21 Days
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
2
States / cities
Palo Alto, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Phase 2Phase 3 Interventional

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity

NCT01203436
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Blindness
Interventions
Supplemental Oxygen Management, Conventional Oxygen Management
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
649 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 1999
U.S. locations
9
States / cities
Palo Alto, California • New Haven, Connecticut • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Not applicable Interventional

Premature Infants Receiving Milking or Delayed Cord Clamping: PREMOD2

NCT03019367
View directory record Official record
Conditions
Intraventricular Haemorrhage Neonatal, Death; Neonatal
Interventions
Umbilical cord milking UCM, Delayed cord clamping DCC
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 33 Weeks
Enrollment
1,201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
15
States / cities
Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2022 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants.

NCT02878330
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
MEDI8897, Placebo
Drug
Lead sponsor
MedImmune LLC
Industry
Eligibility
Up to 365 Days
Enrollment
1,453 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
60
States / cities
Birmingham, Alabama • Anaheim, California • Downey, California + 53 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Oct 27, 2026, 1:12 AM EDT
Not listed No phase listed Observational

Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy

NCT01855347
View directory record Official record
Conditions
Infant, Premature, Diseases, Hypoxia, Necrotizing Enterocolitis
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Up to 3 Weeks
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Oct 27, 2026, 1:12 AM EDT
Not listed Not applicable Interventional

Bilateral Infant Stimulation Study

NCT06353243
View directory record Official record
Conditions
Parent-Child Relations, Preterm Birth, Stress Reaction, Hospitalism in Children
Interventions
Bilateral alternating stimulation
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study to Evaluate the Efficacy and Safety of Suptavumab (REGN2222) for the Prevention of Medically Attended RSV (Respiratory Syncytial Virus) Infection in Preterm Infants

NCT02325791
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
Suptavumab 30 mg/kg, Placebo Matched to Suptavumab, Suptavumab 30 mg/kg- 1 Dose, Suptavumab 30 mg/kg - 2 Doses
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
Up to 6 Months
Enrollment
1,177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
107
States / cities
Birmingham, Alabama • Mobile, Alabama • Little Rock, Arkansas + 104 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Oct 27, 2026, 1:12 AM EDT
Recruiting Not applicable Interventional

Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment

NCT06266455
View directory record Official record
Conditions
Very Preterm Maturity of Infant, Very Low Birth Weight Infant
Interventions
Standardized Fortification, Adjustable Fortification
Dietary Supplement
Lead sponsor
Children's National Research Institute
Other
Eligibility
Up to 4 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2034
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Phase 4 Interventional

Safety of Manganese Restriction in Neonatal Parenteral Nutrition

NCT04259008
View directory record Official record
Conditions
Infant, Newborn, Disease
Interventions
Manganese omission, 5 mCg/kg/day manganese from "Multitrace-4 Neonatal."
Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 1 Day
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 27, 2026, 1:12 AM EDT
Completed No phase listed Observational

Evaluating Decisional Regret Among Mothers

NCT04074525
View directory record Official record
Conditions
Extreme Prematurity, Birth, Preterm, Pregnancy Preterm
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older · Female only
Enrollment
211 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Phase 2 Interventional Results available

Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)

NCT02344225
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Caffeine citrate, Ibuprofen, Ketorolac
Drug
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
Up to 28 Weeks
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2020 · Synced Oct 27, 2026, 1:12 AM EDT
Not listed Phase 2Phase 3 Interventional

Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease

NCT01721655
View directory record Official record
Conditions
Chronic Lung Disease, Bronchopulmonary Dysplasia
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
West Virginia University Healthcare
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Not applicable Interventional Results available

BPD Saturation TARgeting

NCT03385330
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Chronic Lung Disease
Interventions
LOWER oxygen saturation target group, HIGHER oxygen saturation target group
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
34 Weeks to 44 Weeks
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Oct 27, 2026, 1:12 AM EDT
Completed No phase listed Observational

Electrical Activity of Diaphragm as a Means to Predict Extubation Success in Preterm Infants

NCT02144363
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Not listed
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
1 Hour to 28 Days
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 11, 2016 · Synced Oct 27, 2026, 1:12 AM EDT
Completed Phase 1 Interventional Results available

Intestinal Permeability in Preterm Infants

NCT01756040
View directory record Official record
Conditions
Prematurity, Intestinal Permeability
Interventions
Lactulose -rhamnose solution
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
Up to 4 Days
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 27, 2026, 1:12 AM EDT