Independent directory Public ClinicalTrials.gov records United States
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Showing 97–120 of 748 matching trials from the live ClinicalTrials.gov search.
Conditions
Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
Interventions
Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%, Supplemental oxygen with target saturation of 91 to 95%
Drug · Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
24 Weeks to 27 Weeks
Enrollment
1,316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2016
U.S. locations
22
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Maternal Depressive Disorder Complicating Childbirth, Preterm Birth, Maternal Anxiety Disorder Complicating Childbirth
Interventions
Maternal voice
Other
Lead sponsor
AdventHealth
Other
Eligibility
Up to 3 Weeks
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Premature Birth, Preterm Birth
Interventions
PEA POD Infant Body Composition System
Device
Lead sponsor
Vishal Pandey, M.D.
Other
Eligibility
23 Weeks to 42 Weeks
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Bronchopulmonary Dysplasia
Interventions
Azithromycin, Placebo
Drug
Lead sponsor
Hubert Ballard
Other
Eligibility
Up to 72 Hours
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Preterm Birth, Preterm Labor, Bacteremia, Preterm Premature Rupture of Fetal Membranes
Interventions
Prenatal vitamin-mineral containing 3 mg fluoride, Prenatal vitamin-mineral containing 0 mg fluoride
Drug · Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Not listed Not applicable Interventional Accepts healthy volunteers

Human Milk in Preterm Infants

NCT05228535
Conditions
Preterm Birth
Interventions
Human milk fortifier
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
Up to 4 Days
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Preterm Infant, Cerebral Palsy
Interventions
Supporting Play Exploration and Developmental Intervention (SPEEDI)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
Up to 6 Months
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Richmond, Virginia
Conditions
Prematurity, Respiratory Insufficiency, Pulmonary Hypertension, Respiratory Distress Syndrome, Newborn
Interventions
Aerosolized Normal Saline, Inhaled PGE1
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 7 Days
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
11
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 8 more
Conditions
Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
Interventions
Metformin, Esomeprazole
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
Interventions
Placental/Umbilical Cord Blood sample
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 1 Day
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia

NCT00067613
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Bronchopulmonary Dysplasia (BPD)
Interventions
Benchmarking Management Practices, Standard Management Practices
Other
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 36 Weeks
Enrollment
4,095 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2004
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more
Recruiting Not applicable Interventional Accepts healthy volunteers

taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge

NCT06417385
Conditions
Premature Birth, Breastfeeding, Exclusive, Feeding; Difficult, Newborn
Interventions
taVNS soterix device
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Weeks and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Chlamydia Trachomatis Infection, Neonatal Infection, Preterm Birth, Gonorrhea
Interventions
Chlamydia trachomatis and Neisseria gonorrhoeae screening using the GeneXpert
Other
Lead sponsor
University of Southern California
Other
Eligibility
15 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties, Swallowing Difficulties, Humans, Cohort Studies, Infant, Newborn, Infant, Premature, Nutrition, Pediatric Feeding Disorder, Chronic, Retrospective Studies, Breastfeeding, Mental Health Wellness, Intensive Care Units, Neonatal, Bottle Feeding
Interventions
SMART Tool for Feeding Skill Assessment
Diagnostic Test
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
22 Weeks to 42 Weeks
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Infant, Very Low Birth Weight
Interventions
Similac special care 30, Similac human milk fortifier
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Day to 10 Weeks
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Premature Birth
Interventions
Arabin Pessary
Device
Lead sponsor
Gene Lee, MD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Kansas City, Kansas • Charleston, South Carolina
Conditions
Prematurity
Interventions
DHA oil, (MCT) Control oil
Dietary Supplement
Lead sponsor
Sanford Health
Other
Eligibility
24 Weeks to 33 Weeks
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Active, not recruiting Phase 3 Interventional Results available

The Budesonide in Babies (BiB) Trial

NCT04545866
Conditions
Bronchopulmonary Dysplasia (BPD), Respiratory Distress Syndrome, Prematurity; Extreme, Neonatal
Interventions
budesonide (Pulmicort nebulizing suspension)., surfactant (poractant alfa;Curosurf)
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
19
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 15 more
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity

NCT00634972
Conditions
Retinopathy of Prematurity, Retinal Detachment, Blindness
Interventions
ACULAR, REFRESH TEARS, placebo
Drug
Lead sponsor
University of South Alabama
Other
Eligibility
10 Days to 15 Days
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Mobile, Alabama
Conditions
Premature; Infant, Light-for-dates
Interventions
Protein supplementation, Standard fortification
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Minute to 1 Year
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions
Laparotomy, Drainage
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 8 Weeks
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
22
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more
Completed Not applicable Interventional

Preterm Infant Growth

NCT01162798
Conditions
Growth, Development, Infant
Interventions
infant formula, control infant formula
Other
Lead sponsor
Société des Produits Nestlé (SPN)
Industry
Eligibility
Up to 1 Month
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
9
States / cities
Oakland, California • Park Ridge, Illinois • Iowa City, Iowa + 6 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Glycerin Suppositories to Reduce Jaundice in Premature Infants

NCT01746511
Conditions
Idiopathic Hyperbilirubinemia, Neonatal Hyperbilirubinemia, Prematurity
Interventions
Phototherapy, glycerin suppository
Procedure · Drug
Lead sponsor
University of Rochester
Other
Eligibility
30 Weeks to 35 Weeks
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, New York