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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:00 AM EDT

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Showing 145–168 of 809 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Preterm Labor Clear all
Terminated Phase 2 Interventional Results available

Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)

NCT01467076
View directory record Official record
Conditions
Prematurity, Respiratory Insufficiency, Pulmonary Hypertension, Respiratory Distress Syndrome, Newborn
Interventions
Aerosolized Normal Saline, Inhaled PGE1
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 7 Days
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
11
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Oct 21, 2026, 4:00 AM EDT
Completed No phase listed Observational

Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes

NCT00342667
View directory record Official record
Conditions
Preterm Birth, Pregnancy
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Up to 45 Years
Enrollment
4,673 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2014
U.S. locations
2
States / cities
Bethesda, Maryland • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 21, 2026, 4:00 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Phospholipase A2 Producing Bacteria and Pre-Term Labor

NCT00855543
View directory record Official record
Conditions
Preterm Labor
Interventions
Not listed
Lead sponsor
CAMC Health System
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 21, 2026, 4:00 AM EDT
Completed No phase listed Observational

US and Neurodevelopmental Outcomes in the Neonatal Intensive Care Unit (NICU)

NCT05071508
View directory record Official record
Conditions
Premature Birth
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
25 Weeks to 34 Weeks
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Omega-3 Fatty Acids for Smoking Cessation in Pregnancy

NCT04417595
View directory record Official record
Conditions
Preterm Labor, Tobacco Use Disorder
Interventions
Fish Oil (Containing Omega-3 Acids), Olive Oil
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
16 Years to 40 Years · Female only
Enrollment
237 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Phase 2 Interventional Results available

The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor

NCT00404768
View directory record Official record
Conditions
Obstetric Labour, Premature
Interventions
GSK221149A, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
32
States / cities
Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 26 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Not applicable Interventional

Neuroendocrine Mechanisms of Developmental Massage Therapy (DMT) in Preterm Infants: Clinical Study

NCT00722943
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Developmental Massage Therapy, no intervention
Other
Lead sponsor
University of Utah
Other
Eligibility
Up to 14 Days
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 8, 2013 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanical Environment Pregnancy With Short Cervix

NCT03865108
View directory record Official record
Conditions
Preterm Birth
Interventions
Ultrasound imaging, Cervical speculum examination
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Oct 21, 2026, 4:00 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Immunogenicity of PCV-7 Vaccine in VLBW Infants

NCT00273325
View directory record Official record
Conditions
Pneumococcal Infections, Streptococcus Pneumoniae, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 3 Months
Enrollment
368 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
10
States / cities
Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Phase 4 Interventional

Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress

NCT00486850
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Extubation to Nasal IPPV
Other
Lead sponsor
University of Southern California
Other
Eligibility
10 Minutes to 120 Minutes
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
4
States / cities
Los Angeles, California • San Diego, California • Augusta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2009 · Synced Oct 21, 2026, 4:00 AM EDT
Not listed No phase listed Observational

Vibroacoustic Study of Lung Development in Newborn Infants

NCT05827250
View directory record Official record
Conditions
Prematurity, Premature Birth, Premature Lungs, Prematurity; Extreme
Interventions
imPulse Tor
Device
Lead sponsor
Level 42 AI, Inc.
Industry
Eligibility
0 Years to 2 Years
Enrollment
200 participants
Timeline
2023 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants

NCT02943746
View directory record Official record
Conditions
Premature Infants
Interventions
Standard Protein Diet, High Protein Diet
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
14 Days and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 21, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm

NCT06334107
View directory record Official record
Conditions
Preterm Birth
Interventions
Exercise
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 21, 2026, 4:00 AM EDT
Recruiting Not applicable Interventional

Maternal Stress on Human Milk and Infant Outcomes

NCT04821544
View directory record Official record
Conditions
Postpartum Depression, Preterm Labor
Interventions
Mindfulness-based intervention (with a focus on self-compassion; MBSC), Vitamin D
Behavioral · Dietary Supplement
Lead sponsor
University of Idaho
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Coeur d'Alene, Idaho
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 21, 2026, 4:00 AM EDT
Not listed Phase 2 Interventional

Preterm Fetal Growth Restriction and Developmental Care

NCT00166660
View directory record Official record
Conditions
Preterm Birth
Interventions
NIDCAP (Newborn Individualized Developmental Care)
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
28 Weeks to 33 Weeks
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2009 · Synced Oct 21, 2026, 4:00 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Late Preterm Corticosteroids and Neonatal Hypoglycemia

NCT04869709
View directory record Official record
Conditions
Neonatal Hypoglycemia, Prematurity
Interventions
Betamethasone Sodium Phosphate
Drug
Lead sponsor
University of Southern California
Other
Eligibility
Female only
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 21, 2026, 4:00 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA

NCT04047849
View directory record Official record
Conditions
Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature, Rupture of Membranes; Premature, Affecting Fetus, Preterm Birth, Preterm PROM (Pregnancy), Preterm Labor
Interventions
Antibiotics, oral Azithromycin and oral Amoxicillin
Drug
Lead sponsor
Woman's
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Delayed Cord Clamping in VLBW Infants

NCT01222364
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Standard Cord Clamping, Delayed Cord Clamping
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
0 Minutes to 1 Minute
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000
U.S. locations
4
States / cities
Birmingham, Alabama • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 21, 2026, 4:00 AM EDT
Completed Not applicable Interventional Results available

Aspiration of Residual Gastric Contents

NCT01863043
View directory record Official record
Conditions
Infant, Premature, Nutrition, Enteral
Interventions
No aspiration of gastric contents, Routine aspiration of gastric contents
Procedure
Lead sponsor
University of Florida
Other
Eligibility
Up to 3 Days
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Oct 21, 2026, 4:00 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

The Effect of Sulfasalazine on CRH Levels in Pregnant Women

NCT05703425
View directory record Official record
Conditions
Preterm Birth
Interventions
Sulfasalazine
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 4:00 AM EDT
Completed No phase listed Observational

A Multicenter Assessment of a Spontaneous Preterm Birth Risk Predictor

NCT02787213
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Sera Prognostics, Inc.
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
5,011 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
18
States / cities
Phoenix, Arizona • Orange, California • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Oct 21, 2026, 4:00 AM EDT
Not listed No phase listed Observational

Preterm Delivery Risk Prediction by Measurement of Prenatal Serum Screening Markers

NCT01009723
View directory record Official record
Conditions
Preterm Delivery
Interventions
Not listed
Lead sponsor
Esoterix Genetic Laboratories, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Westborough, Massachusetts • Santa Fe, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 8, 2012 · Synced Oct 21, 2026, 4:00 AM EDT
Active, not recruiting Not applicable Interventional Results available

Omega Tots Long Term Follow-up

NCT05191823
View directory record Official record
Conditions
Preterm Birth, Child Development
Interventions
Docosahexaenoic Acid + Arachidonic Acid (DHA+AA), Placebo
Drug · Dietary Supplement
Lead sponsor
Sarah Keim
Other
Eligibility
8 Years to 10 Years
Enrollment
377 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 21, 2026, 4:00 AM EDT
Active, not recruiting Not applicable Interventional

Prone Positioning During Delayed Cord Clamping

NCT05507424
View directory record Official record
Conditions
Delayed Cord Clamping
Interventions
Prone Positioning, Supine Positioning
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 21, 2026, 4:00 AM EDT