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Showing 169–192 of 809 matching trials from the live ClinicalTrials.gov search.
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short Cervix

NCT00439374
Conditions
Preterm Delivery, Cervical Length
Interventions
17 alpha-hydroxyprogesterone caproate, Placebo Oil
Drug · Other
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
Female only
Enrollment
657 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
14
States / cities
Birmingham, Alabama • Chicago, Illinois • Detroit, Michigan + 11 more
Conditions
Body Composition, Beneficial
Interventions
Exercise/Social Behavioral
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
29 Weeks to 34 Weeks
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Orange, California
Conditions
Retinopathy of Prematurity (ROP)
Interventions
Ultra-widefield Optical Coherence Tomography (UWF-OCT), Wide-field ophthalmic imaging system
Device
Lead sponsor
Duke University
Other
Eligibility
0 Days to 9 Months
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Not listed Not applicable Interventional Accepts healthy volunteers

Human Milk in Preterm Infants

NCT05228535
Conditions
Preterm Birth
Interventions
Human milk fortifier
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
Up to 4 Days
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Premature Birth, Preterm Birth
Interventions
PEA POD Infant Body Composition System
Device
Lead sponsor
Vishal Pandey, M.D.
Other
Eligibility
23 Weeks to 42 Weeks
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Completed Not applicable Interventional Accepts healthy volunteers

Nourishing Beginnings: Addressing Food Insecurity During Pregnancy

NCT05341960
Conditions
Pregnancy Related, Food Insecurity, Premature Birth, Pregnancy Complications
Interventions
Food Delivery, Financial Support
Behavioral · Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older · Female only
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Prematurity Education in High Risk Pregnancies

NCT03772080
Conditions
Prematurity, High Risk Pregnancy
Interventions
Early counseling of prematurity in high-risk pregnancies.
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Antibiotics and the Prolongation of Pregnancy in Preterm Labor With an Advanced Cervical Exam

NCT00589329
Conditions
Length of Pregnancy Prolongation in Hours
Interventions
erythromycin and metronidazole (antibiotics), placebo
Drug
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Preterm Birth
Interventions
Urine samples
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Prolonged Apnea, Prolonged Bradycardia
Interventions
Infanrix, Pediatrix
Biological
Lead sponsor
American SIDS Institute
Other
Eligibility
56 Days to 60 Days
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
10
States / cities
Austell, Georgia • Marietta, Georgia • Belle Mead, New Jersey + 6 more
Conditions
Retinopathy of Prematurity
Interventions
Omegaven, Standard lipids (primarily omega-6 fatty acids)
Drug · Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
Up to 7 Days
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
La Jolla, California
Conditions
Doula Support, Postpartum, Postpartum Anaemia, Postpartum Depression (PPD)
Interventions
Doula-coordinated, Midwife-delivered postpartum care
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Bronchopulmonary Dysplasia, Prematurity
Interventions
Care coordination by telephone contacts with a nurse
Procedure
Lead sponsor
Wake Forest University
Other
Eligibility
1 Day to 483 Days
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2000
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Meditation for NICU Moms

NCT03574766
Conditions
Breast Feeding, Premature Birth, Stress, Depression, Postpartum, Anxiety, Self Efficacy, Behavior, Maternal, Insufficient Lactation
Interventions
Meditation
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richmond Heights, Missouri
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feeding and Transition to Home for Preterms at Social Risk

NCT02041923
Conditions
Premature Birth
Interventions
H-HOPE, Attention Control
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
2 Hours to 45 Years
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
2
States / cities
Chicago, Illinois
Completed Early Phase 1 Interventional Accepts healthy volunteers

PROMMO Trial: Oral Misoprostol vs IV Oxytocin

NCT04478942
Conditions
Premature Rupture of Membrane, Induction of Labor Affected Fetus / Newborn
Interventions
Misoprostol Oral Product, Intravenous Oxytocin
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Preterm Birth, Low; Birthweight, Extremely (999 Grams or Less)
Interventions
Financial Transfers
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Atlanta, Georgia • Boston, Massachusetts • Springfield, Massachusetts + 1 more
Conditions
Preterm Birth
Interventions
CenteringPregnancy
Behavioral
Lead sponsor
Endeavor Health
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
1,133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Moderate to Late Prematurity
Interventions
Skin-to-Skin contact
Behavioral
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2001
U.S. locations
2
States / cities
Cleveland, Ohio • Richmond, Washington
Conditions
Complication of Prematurity
Interventions
Patterned Experience
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 32 Weeks
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Cincinnati, Ohio
Recruiting No phase listed Observational Accepts healthy volunteers

Genesis Electrical Impedance Tomography (EIT): A Preliminary Study

NCT03797183
Conditions
Premature Infant, Chronic Respiratory Disease, Neuromuscular Diseases, Healthy, Bronchopulmonary Dysplasia, Pulmonary Vein Stenoses
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
14 Days to 40 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Recruiting No phase listed Observational

Growing Little PEAPODS Study

NCT06226051
Conditions
Premature Birth, Premature Infant, Premature, Intrauterine Growth Restriction, Small for Gestational Age at Delivery
Interventions
PEAPOD Infant Body Composition measuring device
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
22 Weeks to 32 Weeks
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Preterm Birth
Interventions
17 alpha-Hydroxyprogesterone Caproate and Omega-3 supplement, 17 alpha-hydroxy progesterone caproate and Placebo supplement
Drug
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
12
States / cities
Birmingham, Alabama • Chicago, Illinois • Detroit, Michigan + 9 more
Completed No phase listed Observational Accepts healthy volunteers

Emotional Experiences in Fathers of NICU Infants

NCT00306605
Conditions
Stress, Depressive Symptomatology
Interventions
Questionnaire
Behavioral
Lead sponsor
Christiana Care Health Services
Other
Eligibility
Male only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
2
States / cities
Newark, Delaware • Wilmington, Delaware