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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:54 AM EDT

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Showing 217–240 of 648 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Preterm Neonates Clear all
Completed Not applicable Interventional

Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)

NCT05319236
View directory record Official record
Conditions
Cardiac Disease, Respiratory Disease, Congenital Cardiac Defect, Cardiovascular Diseases, Chronic Respiratory Disease, Chronic Cardiopulmonary Disease, Premature Infant Disease
Interventions
Gabi System
Device
Lead sponsor
Gabi SmartCare
Industry
Eligibility
Up to 5 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Washington D.C., District of Columbia • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 22, 2026, 4:54 AM EDT
Terminated Phase 4 Interventional Results available

Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants

NCT00767039
View directory record Official record
Conditions
Prematurity, Respiratory Distress Syndrome, Patent Ductus Arteriosus
Interventions
Survanta (beractant), Curosurf (poractant)
Drug
Lead sponsor
Alan Fujii
Other
Eligibility
Up to 8 Hours
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 3, 2011 · Synced Oct 22, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional

Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)

NCT05849077
View directory record Official record
Conditions
Premature Infants, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Neurodevelopmental Outcomes
Interventions
Sat75, Sat50
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
0 Minutes to 10 Minutes
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

BPD Saturation TARgeting

NCT03385330
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Chronic Lung Disease
Interventions
LOWER oxygen saturation target group, HIGHER oxygen saturation target group
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
34 Weeks to 44 Weeks
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Oct 22, 2026, 4:54 AM EDT
Not yet recruiting Not applicable Interventional

Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities

NCT06915428
View directory record Official record
Conditions
Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence, Preeclampsia, Preeclampsia (PE), Hypertensive Disorders of Pregnancy, Support Program, Stress, Resilience, Psychological, Empowerment, Patient, Emotional Stress, Pregnancy, Pregnancy Complications, Pregnancy Induced Hypertension, Neonates and Preterm Infants, Cervical Insufficiency, Social Determinants of Health (SDOH), Cervical Shortening, Disparities in Pregnancy Complications, Disparities, Prenatal Care, Care Coordination
Interventions
Care coordination, Electronic massage, support gift #1, Support gift #2, Support gift #3, Support gift #4, Additional PTBCARE+ support, Stress reduction toolkit - Visit 1 (V1), PTBCARE+ mobile application (app) and website, Sleep, meditation, and Wellness app, Emergency low blood sugar kit, Low dose aspirin (LDA), Visit #2 Stress Reduction Toolkit
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
1,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 22, 2026, 4:54 AM EDT
Not listed Not applicable Interventional

Novel Human Milk Based Human Milk Fortifier

NCT04478487
View directory record Official record
Conditions
Infant, Premature, Diseases
Interventions
Medolac human milk based human milk fortifier (MHMHMF)
Dietary Supplement
Lead sponsor
Northwest Health
Other
Eligibility
23 Weeks to 32 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Johnson, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 22, 2026, 4:54 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Biomarkers Study in Infants With Prior Neonatal Brain Injury

NCT07413900
View directory record Official record
Conditions
HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury, Premature Birth, Healthy Participants
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
3 Months to 24 Months
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Phase 3 Interventional Results available

Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress Syndrome

NCT00244101
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
PS Group, NCPAP Group, ISX Group
Drug · Device
Lead sponsor
Vermont Oxford Network
Network
Eligibility
26 Weeks to 29 Weeks
Enrollment
648 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Oct 22, 2026, 4:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Do Elevated BNP Levels Predict Hemodynamically Significant PDAs

NCT01497054
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
Not listed
Lead sponsor
Albany Medical College
Other
Eligibility
1 Hour to 24 Hours
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jul 4, 2013 · Synced Oct 22, 2026, 4:54 AM EDT
Terminated Not applicable Interventional

Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates

NCT01365312
View directory record Official record
Conditions
Infection Associated With Catheter, Bacteremia, Sepsis
Interventions
Ethanol lock, Heparinized saline
Drug
Lead sponsor
East Carolina University
Other
Eligibility
Up to 32 Weeks
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2014 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants

NCT03694613
View directory record Official record
Conditions
Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
Interventions
Placental/Umbilical Cord Blood sample
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 1 Day
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 22, 2026, 4:54 AM EDT
Active, not recruiting Not applicable Interventional

Prone Positioning During Delayed Cord Clamping

NCT05507424
View directory record Official record
Conditions
Delayed Cord Clamping
Interventions
Prone Positioning, Supine Positioning
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 22, 2026, 4:54 AM EDT
Not listed Not applicable Interventional

Effects of Mother's Voice and Heartbeat Sounds on Preterm Newborns

NCT01913288
View directory record Official record
Conditions
Preterm Birth
Interventions
Biological Maternal Sounds
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
24 Weeks to 34 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Liquid Preterm Formula Versus Powdered Human Milk Fortifier in VLBW Infants

NCT00760942
View directory record Official record
Conditions
Infant, Very Low Birth Weight
Interventions
Similac special care 30, Similac human milk fortifier
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Day to 10 Weeks
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Phase 2 Interventional Results available

Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome

NCT01941745
View directory record Official record
Conditions
Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia
Interventions
Half normal saline, Low Dose rhCC10, High dose rhCC10
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
24 Weeks to 29 Weeks
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
3
States / cities
Boston, Massachusetts • Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 22, 2026, 4:54 AM EDT
Withdrawn Phase 1 Interventional

Inhaled Treatment for Bronchopulmonary Dysplasia

NCT04619602
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
GSNO
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
29 Days to 365 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Phase 1 Interventional

A Clinical Safety Study of AT-100 (rhSP-D) in Preterm Neonates at High Risk for Bronchopulmonary Dysplasia (BPD)

NCT04662151
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
AT-100, Air-sham
Biological · Procedure
Lead sponsor
Airway Therapeutics, Inc.
Industry
Eligibility
0 Minutes to 96 Hours
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
9
States / cities
Tucson, Arizona • Little Rock, Arkansas • Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

A Clinical Trial of A Pacifier-Activated Music Player

NCT01600586
View directory record Official record
Conditions
Prematurity
Interventions
Pacifier-Activated-Lullaby system (PAL).
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
34 Weeks to 36 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 22, 2026, 4:54 AM EDT
Terminated Not applicable Interventional Results available

Proparacaine and Mydriatic Eye Drops

NCT01266824
View directory record Official record
Conditions
Pain, Retinopathy of Prematurity
Interventions
Proparacaine Hydrochloride Ophthalmic Solution
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Phase 1 Interventional Results available

Inhaled Tobramycin in BPD

NCT04560179
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Tobramycin solution for inhalation 78mg dose, Tobramycin solution for inhalation 150mg dose, Tobramycin solution for inhalation 216mg dose, Tobramycin solution for inhalation 300mg dose
Drug
Lead sponsor
Erik Allen Jensen
Other
Eligibility
4 Weeks and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19

NCT04718220
View directory record Official record
Conditions
Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus, Neonatal Infection, Prenatal Stress, Preterm Birth
Interventions
Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Delayed Clamping and Milking the Umbilical Cord in Preterm Infants

NCT02092103
View directory record Official record
Conditions
Premature Birth
Interventions
Cord Milking
Procedure
Lead sponsor
TriHealth Inc.
Other
Eligibility
Not listed
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 28, 2018 · Synced Oct 22, 2026, 4:54 AM EDT
Active, not recruiting Not applicable Interventional

Cycled Phototherapy

NCT03927833
View directory record Official record
Conditions
Hyper Bilirubinemia, Premature Infant
Interventions
Phototherapy lights
Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
22 Weeks to 27 Weeks
Enrollment
1,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
19
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 22, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Neuroendocrine Mechanisms of Developmental Massage Therapy (DMT) in Preterm Infants: Clinical Study

NCT00722943
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Developmental Massage Therapy, no intervention
Other
Lead sponsor
University of Utah
Other
Eligibility
Up to 14 Days
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 8, 2013 · Synced Oct 22, 2026, 4:54 AM EDT