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ClinicalTrials.gov public records Last synced Sep 21, 2026, 6:03 AM EDT

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Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prevention of Colorectal Cancer Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Adherence to Colon Cancer Screening (ACCS)

NCT02112747
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
Patient Navigator
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
25 Years to 75 Years
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Results available

Quality Improvement of Patient-Provider Communication For Colorectal Cancer Screening

NCT00324753
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Communication, Standard of care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 74 Years
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
3
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Phase 1 Interventional

Curcumin for the Prevention of Colon Cancer

NCT00027495
View directory record Official record
Conditions
Colorectal Cancer
Interventions
curcumin
Dietary Supplement
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Phase 2 Interventional Results available

Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan

NCT00748215
View directory record Official record
Conditions
Chemotherapeutic Agent Toxicity, Colorectal Cancer, Diarrhea
Interventions
calcium aluminosilicate anti-diarrheal, placebo
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Portland, Oregon • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2020 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Touch 2 Screen" Multi-media Colorectal Cancer Screening Intervention

NCT00594113
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Touch 2 Screen, Touch screen intervention
Other
Lead sponsor
Allen A. Greiner, MD, MPH
Other
Eligibility
50 Years and older
Enrollment
470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 19, 2012 · Synced Sep 21, 2026, 6:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

GI SPORE Colon Biosample Protocol

NCT02243267
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
sample collection
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Phase 2 Interventional

Calcium and Vitamin D vs Markers of Adenomatous Polyps

NCT00208793
View directory record Official record
Conditions
Colorectal Adenomatous Polyps
Interventions
Calcium and vitamin D3 combined, Placebo, Calcium, Vitamin D3
Dietary Supplement · Drug
Lead sponsor
Emory University
Other
Eligibility
30 Years to 74 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Magnesium Treatment on Vitamin D Metabolism in Participants Completed Personalized Prevention of Colorectal Cancer Trial

NCT03265483
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Magnesium glycinate, Placebo
Dietary Supplement
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 21, 2026, 6:03 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

End of Life Treatment Preferences of Latino Medicare Beneficiaries With Cancer

NCT01389830
View directory record Official record
Conditions
Advanced Cancers
Interventions
Telephone Survey
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 21, 2026, 6:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

NCT07106359
View directory record Official record
Conditions
Cascade Testing, Lynch Syndrome, Decision Making, Colorectal Cancer, Uterine Cancer, Cancer Prevention
Interventions
Information Letter and Booklet, Information Letter
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy

NCT01113736
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
AlloMEM™
Biological
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Eating for Colon Cancer Prevention

NCT00475722
View directory record Official record
Conditions
Colon Cancer
Interventions
1 Healthy Eating, 2 Mediterranean
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2016 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Colonoscopic Removal of Aberrant Crypt Foci: a Prospective, Randomized, Blinded Trial

NCT00623883
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Surgical removal of ACF, Colonoscopic evaluation only
Procedure
Lead sponsor
National Naval Medical Center
Federal
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2008 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care

NCT03460483
View directory record Official record
Conditions
Endometrial Adenocarcinoma, Endometrial Carcinoma, Lynch Syndrome, Relatives
Interventions
Genetic Counseling, Genetic Testing, Laboratory Biomarker Analysis, Mutation Carrier Screening
Other · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1,001 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
9
States / cities
Akron, Ohio • Canton, Ohio • Cincinnati, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 21, 2026, 6:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)

NCT06682650
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
NPT-PLA, Usual Quality Improvement
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
2,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Phase 1 Interventional

Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab

NCT04164069
View directory record Official record
Conditions
Advanced Colorectal Carcinoma, Metastatic Colorectal Carcinoma, Stage IV Colorectal Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8, Stage IVB Colorectal Cancer AJCC v8, Stage IVC Colorectal Cancer AJCC v8, Stage II Colon Cancer, Stage II Rectal Cancer, Stage III Colon Cancer, Stage III Rectal Cancer, Esophageal Cancer, Pancreatic Cancer, Bile Duct Cancer, Gastric Cancer, Gall Bladder Cancer, Small Bowel Adenocarcinoma
Interventions
Bevacizumab, Dasatinib, Fluorouracil, Leucovorin, Leucovorin Calcium, Oxaliplatin, Quality-of-Life Assessment
Biological · Drug · Other
Lead sponsor
Anne Noonan
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study

NCT01310699
View directory record Official record
Conditions
Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
Interventions
Olympus Colonoscope CFHQ190AL
Device
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
281 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
3
States / cities
Palo Alto, California • San Francisco, California • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Electronic Health Record-Based Interventions for Improving Follow-Up in Primary Care

NCT01346839
View directory record Official record
Conditions
Colon Cancer, Lung Cancer, Prostate Cancer
Interventions
Contact Intervention
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
1,256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Houston, Texas • Temple, Texas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Precision-Based Magnesium Trial

NCT01105169
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Magnesium glycinate, Placebo
Dietary Supplement
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 21, 2026, 6:03 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Phase I Biomarker Study of Dietary Grape-derived Low Dose Resveratrol for Colon Cancer Prevention

NCT00578396
View directory record Official record
Conditions
Colon Cancer
Interventions
grapes
Dietary Supplement
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 21, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening

NCT00810771
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Standard Information, Preference-tailored Information
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 78 Years
Enrollment
466 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Sep 21, 2026, 6:03 AM EDT
Not yet recruiting Phase 2 Interventional

SAMe in Prevention of Oxaliplatin-associated Liver Injury

NCT06258525
View directory record Official record
Conditions
Colorectal Cancer, Liver Metastases, Liver Metastasis Colon Cancer, Liver Injury, Sinusoidal Obstruction Syndrome, 5-Fluorouracil Toxicity, Liver Toxicity, Chemically-Induced
Interventions
Standard of care oxaliplatin-based chemotherapy, S-adenosylmethionine (SAMe) supplement, Surgery
Radiation · Dietary Supplement · Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 21, 2026, 6:03 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Colon Cancer Prevention Using Selenium

NCT01211561
View directory record Official record
Conditions
Prevention of Colorectal Cancer
Interventions
Selenium, selenomethionine, placebo
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2010 · Synced Sep 21, 2026, 6:03 AM EDT
Active, not recruiting Phase 3 Interventional

S0820, Adenoma and Second Primary Prevention Trial

NCT01349881
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Eflornithine placebo & sulindac placebo, eflornithine & sulindac placebo, Eflornithine placebo & sulindac, Eflornithine plus sulindac
Drug
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2032
U.S. locations
990
States / cities
Birmingham, Alabama • Anchorage, Alaska • Fairbanks, Alaska + 617 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 21, 2026, 6:03 AM EDT