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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 74 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Primary Medical Care Clear all

Conditions: Patient-centered Medical Home Implementation
Interventions: Multilevel stakeholder engagement, Quality improvement (QI) education/training, Technical support, Formative feedback, External practice facilitation, National policy guidance; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 3,900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 13
States / cities: Sepulveda, California • West Haven, Connecticut • Chicago, Illinois + 10 more

Conditions: HIV Infection
Interventions: Pre-Exposure Prophylaxis (PrEP); Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Alcohol-Related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse, Alcohol Use Disorders
Interventions: Motivation Enhancement Therapy, Modified Behavioral Self-Control Therapy, Naltrexone, Brief Advice, Referral to specialty substance use disorder treatment; Behavioral · Drug · Other
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 75 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Great Neck, New York

Conditions: Opioid-Related Disorders
Interventions: G-BMT, Treatment as usual, Buprenorphine; Behavioral · Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Advance Care Planning, Primary Health Care
Interventions: ENACT group visit, Mailed Resources; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 516 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Aurora, Colorado • Boulder, Colorado • Denver, Colorado + 3 more

Conditions: Diabetes
Interventions: Weight management, Shared medical appointments (SMA); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 263 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Primary Health Care, Quality of Health Care, Comorbidity, Communication, Medical Informatics Applications
Interventions: Visit Planner, Attention Control Pamphlet, iPad; Behavioral · Other · Device
Lead sponsor: Kaiser Permanente; Other
Eligibility: 30 Years and older
Enrollment: 750 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Oakland, California

Conditions: Type II Diabetes, Primary Health Care, Behavioral Health
Interventions: INTEGRATE-D; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 294 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Osteo Arthritis Knee, Knee Arthritis, Monitoring Orthopedic Devices, Total Knee Arthroplasty, Total Knee Replacement
Interventions: Persona IQ; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 4
States / cities: Granger, Indiana • St Louis, Missouri • Charlotte, North Carolina + 1 more

Conditions: Health Knowledge, Attitudes, Practice, Health Care Utilization
Interventions: Patient education materials, Physician peer-comparison email, Physician education materials, General visit preparation materials; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 329 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Opioid Dependence, Substance Abuse Disorders, Complex Medical Patients, Primary Care Patients With Chronic Conditions
Interventions: MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing); Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Prediabetes
Interventions: ADAPT tool; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Medical Education
Interventions: Online education; Behavioral
Lead sponsor: Medical Directions, Inc; Industry
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Breast Cancer, Colorectal Cancer, Cervical Cancer
Interventions: TopCare: Use of provider knowledge vs. automated system; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 21 Years to 75 Years
Enrollment: 103,870 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Opiate Overdose, Opioid-Related Disorders, Narcotic-Related Disorders, Substance-related Disorders, Chemically-Induced Disorders, Mental Disorders
Interventions: Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 674 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Chronic Pain
Interventions: Group Acupuncture, Integrative Group Medical Visits; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver, Cancer of Stomach, Cancer Liver, Cancer of Rectum, Cancer of Kidney, Cancer of Esophagus, Cancer of Cervix, Cancer of Colon, Cancer of Larynx, Cancer, Lung, Cancer, Breast, Cancer, Advanced, Cancer Prostate, Cancer of Neck, Cancer of Skin, Neuroendocrine Tumors, Carcinoma, Mismatch Repair Deficiency, BRCA Gene Rearrangement, Non Hodgkin Lymphoma, Leukemia, Non Small Cell Lung Cancer, Cholangiocarcinoma, Glioblastoma, Central Nervous System Tumor, Melanoma, Urothelial Carcinoma, Bladder Cancer, Ovarian Cancer, Endometrial Cancer, Testicular Cancer, Breast Cancer, COVID, Myelofibrosis, Myeloproliferative Neoplasm, Myeloproliferative Disorders, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Myelodysplastic Syndromes
Interventions: Clinical Trial Matching; Other
Lead sponsor: Massive Bio, Inc.; Industry
Eligibility: Not listed
Enrollment: 50,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2040
U.S. locations: 67
States / cities: Birmingham, Alabama • Mobile, Alabama • Scottsdale, Arizona + 64 more

Conditions: Chronic Illness
Interventions: videoconferencing; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Chronic Pain
Interventions: group acupuncture, Integrative Group Medical Visits; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Interventions: Home-based palliative care, Enhanced usual care; Other
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alcohol Dependence
Interventions: XR-NTX (Extended-Release Naltrexone), Oral Naltrexone (O-NTX); Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 237 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Use Disorder, Unspecified Adult Solid Tumor, Protocol Specific
Interventions: smoking cessation intervention, counseling intervention; Behavioral · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 5
States / cities: Aurora, Colorado • Honolulu, Hawaii • Boston, Massachusetts + 1 more

Conditions: Alcohol Abuse
Interventions: Brief Advice, NIAAA Clinician's Guide, Motivational Interviewing (MI); Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Decision Support Systems, Clinical, Referral and Consultation
Interventions: SAGE (AI clinical decision support), Standard eConsult; Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Stanford, California

Search by objective public record fields.

Implementation of Women's Health Patient Aligned Care Teams

MAPS PrEP Van Study

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

Buprenorphine Group Medical Visits in Primary Care

Effectiveness of Engaging in Advance Care Planning Talks (ENACT) Group Visits in Primary Care for Older Adults With and Without Alzheimer's Disease

Jump Start Shared Medical Appointments for Diabetes With Weight Management

Aligning Patients and Their Primary Care Providers

INTEGRATE-D: A Pilot Test to Support Integration of Medical and Psychosocial Care for People With Type II Diabetes

Persona IQ Cohort Study

Shared Decision-making on Medical Tests and Care Cascades

The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care

The Avoiding Diabetes Thru Action Plan Targeting Pilot Randomized Control Trial

Online Primary Care Physician (PCP) Training in Screening, Brief Intervention, Referral, and Treatment

Population-Based Patient-Centric Care: Comprehensive Preventive Cancer Screening Using Health IT

Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care

Group-based Integrative Pain Management in Primary Care Safety Net Clinics

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Virtually-integrated Co-management Between Complex Care and Community-based Primary Care Providers

Group-based Integrative Pain Management (IPMP+ Pilot)

Expanding Access to Home-Based Palliative Care

Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care

Primary Care Physicians' Use of Stop-Smoking Plans to Help Patients Who Are Smokers

Mentored Research on Improving Alcohol Brief Interventions in Medical Settings

Testing an AI Tool to Help Primary Care Clinicians With Specialty Consultation Questions