- Conditions
- Glaucoma, Open-Angle
- Interventions
- VVN539 Ophthalmic Solution 0.02%, VVN539 Ophthalmic Solution 0.04%, VVN539 Ophthalmic Solution Vehicle
- Drug
- Lead sponsor
- VivaVision Biotech, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
Search Results
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Showing 1–24
of 157
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension
- Interventions
- Stage 1 - ATS907 - Dose 1, Stage 1 - ATS907 - Dose 2, Stage 1 - ATS907 - Dose 3, Stage 1 - ATS907 - Dose 4, Stage 1 - Vehicle, Stage 2 - ATS907 - Dose A - to be selected based on Stage 1, Stage 2 - ATS907 - Dose B - to be selected based on Stage 1, Timoptic
- Drug
- Lead sponsor
- Altheos, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 5
- States / cities
- Artesia, California • Glendale, California • Saint Joseph, Michigan + 2 more
- Conditions
- Primary Open Angle Glaucoma, Cataract
- Interventions
- CyPass Micro-Stent, Cataract Surgery
- Device · Procedure
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 12
- States / cities
- Glendale, Arizona • Orange, California • Fort Collins, Colorado + 9 more
- Conditions
- Ocular Hypertension, Glaucoma
- Interventions
- AGN-210669 ophthalmic solution, 0.075%, AGN-210669 ophthalmic solution, 0.05%, AGN-210669 ophthalmic solution, 0.025%, bimatoprost ophthalmic solution 0.03%, AGN-210669 vehicle ophthalmic solution
- Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 172 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Artesia, California
- Conditions
- Glaucoma, Ocular Hypertension
- Interventions
- RKI983A, Latanoprost
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 276 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 29
- States / cities
- Artesia, California • Inglewood, California • La Jolla, California + 25 more
- Conditions
- Primary Open-angle Glaucoma (POAG), Ocular Hypertension
- Interventions
- SHP639 (n=60), Placebo Comparator (n=24)
- Drug
- Lead sponsor
- Shire
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Lexington, Massachusetts
- Conditions
- Glaucoma
- Interventions
- Phacoemulsification with implantation of intraocular lens (CE-IOL) SENSIMED Triggerfish
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Glaucoma
- Interventions
- Travoprost 0.004%/timolol maleate 0.5% fixed combination
- Drug
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Glaucoma
- Interventions
- Observation only
- Other
- Lead sponsor
- Peregrine Ophthalmic
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Goose Creek, South Carolina
- Conditions
- Primary Open Angle Glaucoma, Healthy Subjects
- Interventions
- SENSIMED Triggerfish
- Device
- Lead sponsor
- Sensimed AG
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension
- Interventions
- Voyager DSLT
- Device
- Lead sponsor
- The Eye Institute of West Florida
- Other
- Eligibility
- Not listed
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Largo, Florida
- Conditions
- Glaucoma, Ocular Hypertension, Eye Disease
- Interventions
- AMA0076, Placebo
- Drug
- Lead sponsor
- Amakem, NV
- Industry
- Eligibility
- 30 Years to 85 Years
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 9
- States / cities
- Artesia, California • Inglewood, California • Petaluma, California + 6 more
- Conditions
- Glaucoma, Ocular Hypertension
- Interventions
- RKI983
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Timeline
- Started 2007
- U.S. locations
- 5
- States / cities
- Artesia, California • Rochester, New York • Charlotte, North Carolina + 2 more
- Conditions
- Primary Open Angle Glaucoma
- Interventions
- Not listed
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,540 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2022
- U.S. locations
- 3
- States / cities
- Birmingham, Alabama • La Jolla, California • New York, New York
- Conditions
- Glaucoma; Drugs, Normal Tension Glaucoma, Primary Open-angle Glaucoma
- Interventions
- Timolol Maleate, Brimonidine Tartrate
- Drug
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Glaucoma, Open-Angle
- Interventions
- Methazolamide 25 MG, Methazolamide 50 MG
- Drug
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma; Drugs, Droopy Eyelid, Ptosis, Glaucoma, Primary Open Angle
- Interventions
- brimonidine tartrate ophthalmic solution 0.025%, sterile balanced saline solution
- Drug · Other
- Lead sponsor
- Tulane University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2036
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Primary Open Angle Glaucoma
- Interventions
- Glaucoma Surgery, InnFocus MicroShunt
- Procedure · Device
- Lead sponsor
- InnFocus Inc.
- Industry
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 732 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 24
- States / cities
- Glendale, Arizona • Tucson, Arizona • Fayetteville, Arkansas + 21 more
- Conditions
- Glaucoma, Primary Open Angle
- Interventions
- ELIOS Procedure
- Device
- Lead sponsor
- Elios Vision, Inc.
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 318 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 20
- States / cities
- Glendale, Arizona • Petaluma, California • Fort Collins, Colorado + 16 more
- Conditions
- Primary Open-Angle Glaucoma
- Interventions
- Stents, Laser, Laser Trabeculoplasty
- Device · Procedure
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 35 Years and older
- Enrollment
- 91 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 9
- States / cities
- Glendale, Arizona • Fayetteville, Arkansas • Hemet, California + 6 more
- Conditions
- Primary Open-angle Glaucoma
- Interventions
- Questionnaires
- Other
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Primary Open Angle Glaucoma or Ocular Hypertension
- Interventions
- Netarsudil ophthalmic solution 0.02%, Artificial tears
- Drug
- Lead sponsor
- East Coast Institute for Research
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Glaucoma, Open-Angle, Ocular Hypertension
- Interventions
- AGN-207281 ophthalmic solutions (0.1% and 0.3%); AGN-207281 vehicle ophthalmic solution (placebo), timolol ophthalmic solution 0.5%, AGN-207281 vehicle ophthalmic solution (Placebo)
- Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Newport Beach, California
- Conditions
- Primary Open Angle Glaucoma
- Interventions
- dietary supplement with antioxidants, Placebo
- Dietary Supplement
- Lead sponsor
- ScienceBased Health
- Industry
- Eligibility
- 30 Years to 70 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana