- Conditions
- Primary Open Angle Glaucoma
- Interventions
- GlaucoCetin, Placebo
- Dietary Supplement · Other
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
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Showing 1–24
of 99
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Primary Open-angle Glaucoma and Ocular Hypertension
- Interventions
- DE-117 Ophthalmic Solution
- Drug
- Lead sponsor
- Santen Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 107 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 32
- States / cities
- Chandler, Arizona • Glendale, California • Mission Hills, California + 28 more
- Conditions
- Glaucoma, Ocular Hypertension
- Interventions
- Latanoprost-PPDS
- Drug
- Lead sponsor
- Mati Therapeutics Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 8
- States / cities
- Artesia, California • Sacramento, California • Bel Air, Maryland + 5 more
- Conditions
- Primary Open Angle Glaucoma
- Interventions
- Not listed
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 0 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Primary Open Angle Glaucoma
- Interventions
- Glaucoma Surgery, InnFocus MicroShunt
- Procedure · Device
- Lead sponsor
- InnFocus Inc.
- Industry
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 732 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 24
- States / cities
- Glendale, Arizona • Tucson, Arizona • Fayetteville, Arkansas + 21 more
- Conditions
- Primary Open-Angle Glaucoma, Unspecified Eye, Ocular Hypertension
- Interventions
- Selective Laser Trabeculoplasty
- Device
- Lead sponsor
- Northeastern State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Tahlequah, Oklahoma
- Conditions
- Open-angle Glaucoma or Ocular Hypertension
- Interventions
- DE-117 ophthalmic solution, latanoprost ophthalmic solution, Placebo
- Drug · Other
- Lead sponsor
- Santen Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 91 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 7
- States / cities
- Newport Beach, California • Morrow, Georgia • Kansas City, Missouri + 4 more
- Conditions
- Glaucoma and Ocular Hypertension
- Interventions
- DE-117, 0.0015% tafluprost, DE-117 and 0.0015% tafluprost, Placebo
- Drug
- Lead sponsor
- Santen Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 10
- States / cities
- Newport Beach, California • Deerfield Beach, Florida • Largo, Florida + 7 more
- Conditions
- Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma, Traumatic Glaucoma, Uveitic Glaucoma, Neovascular Glaucoma
- Interventions
- Molteno 3 glaucoma drainage shunt
- Procedure
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Primary Open-angle Glaucoma, Ocular Hypertension
- Interventions
- LX7101 (0.125%), LX7101 (0.25%), LX7101 Vehicle
- Drug
- Lead sponsor
- Lexicon Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 5
- States / cities
- Morrow, Georgia • Memphis, Tennessee • Austin, Texas + 2 more
- Conditions
- Glaucoma, Open-Angle
- Interventions
- H-1337 Placebo, H-1337 [1], H-1337 [2], H-1337 [3]
- Drug
- Lead sponsor
- Allysta Pharmaceutical
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Goose Creek, South Carolina
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension
- Interventions
- Stage 1 - ATS907 - Dose 1, Stage 1 - ATS907 - Dose 2, Stage 1 - ATS907 - Dose 3, Stage 1 - ATS907 - Dose 4, Stage 1 - Vehicle, Stage 2 - ATS907 - Dose A - to be selected based on Stage 1, Stage 2 - ATS907 - Dose B - to be selected based on Stage 1, Timoptic
- Drug
- Lead sponsor
- Altheos, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 5
- States / cities
- Artesia, California • Glendale, California • Saint Joseph, Michigan + 2 more
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension
- Interventions
- Brimonidine purite 0.15%, Dorzolamide 2%, Brinzolamide 1%
- Drug
- Lead sponsor
- Northwestern Ophthalmic Institute S.C.
- Other
- Eligibility
- 41 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Glenview, Illinois
- Conditions
- Glaucoma
- Interventions
- Silicone plate Ahmed Glaucoma Valve (Model FP7), Porous Plate Ahmed Glaucoma Valve (Model M4)
- Device
- Lead sponsor
- Peter Netland, MD
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Glaucoma Open-Angle Primary, Ocular Hypertension
- Interventions
- H-1337 0.6%, H-1337 1.0%, H-1337 Placebo, Timolol 0.5%
- Drug
- Lead sponsor
- D. Western Therapeutics Institute, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 201 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 9
- States / cities
- Glendale, California • Colorado Springs, Colorado • Lakeland, Florida + 6 more
- Conditions
- Primary Open Angle Glaucoma
- Interventions
- Life Space Questionnaire, Low Luminance Questionnaire, Contrast sensitivity under dim illumination, Visual field under dim illumination (MAIA), Macular Pigment Optical Density (MPOD), Dark Adaptation
- Diagnostic Test
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Primary Open Angle Glaucoma (POAG), Ocular Hypertension (OHT)
- Interventions
- Latanoprost, Arm 2, Latanoprost SR insert
- Drug
- Lead sponsor
- Daniel Moore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Open Angle Glaucoma
- Interventions
- 2.5mg ANX007, 5.0mg ANX007, Sham Procedure
- Biological · Other
- Lead sponsor
- Annexon, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 2
- States / cities
- Newport Beach, California • Stanford, California
- Conditions
- Glaucoma, Glaucoma, Open Angle
- Interventions
- AqueSys XEN 45 Glaucoma Implant
- Device
- Lead sponsor
- AqueSys, Inc.
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 12
- States / cities
- Glendale, Arizona • Fayetteville, Arkansas • Montebello, California + 9 more
- Conditions
- Glaucoma, Primary Open Angle Glaucoma, Glaucoma, Suspect
- Interventions
- Collection of genetic material
- Diagnostic Test
- Lead sponsor
- Duke University
- Other
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 1,152 participants
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Glaucoma, Ocular Hypertension, Eye Disease
- Interventions
- AMA0076, Placebo
- Drug
- Lead sponsor
- Amakem, NV
- Industry
- Eligibility
- 30 Years to 85 Years
- Enrollment
- 82 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 6
- States / cities
- Artesia, California • Inglewood, California • Petaluma, California + 3 more
- Conditions
- Glaucoma, Open-Angle
- Interventions
- OMNI® Surgical System
- Device
- Lead sponsor
- Sight Sciences, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 10
- States / cities
- Atlanta, Georgia • Wichita, Kansas • Bloomington, Minnesota + 7 more
- Conditions
- Open-angle Glaucoma
- Interventions
- ANX007
- Biological
- Lead sponsor
- Annexon, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Newport Beach, California
- Conditions
- Primary Open Angle Glaucoma
- Interventions
- OMNI Surgical System, Latanoprost plus adjunctive glaucoma medication
- Device · Drug
- Lead sponsor
- Sight Sciences, Inc.
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 2
- States / cities
- Petaluma, California • Maryville, Tennessee