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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:42 PM EDT

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Showing 289–312 of 1,450 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Primary Parkinsonism Clear all
Completed No phase listed Observational

PET Scanning in Parkinson s Disease

NCT00024622
View directory record Official record
Conditions
Schizophrenia, Parkinson's Disease
Interventions
O-15 Water, 18F-Fluoro-L-dopa
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 90 Years
Enrollment
502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Not applicable Interventional Results available

Deep Brain Stimulation (DBS) for the Treatment of Parkinson's Disease

NCT01839396
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years to 75 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
22
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Phase 1Phase 2 Interventional

Study of NP002 in Subjects With Idiopathic Parkinson's Disease to Treat Dyskinesias Due to Levodopa Therapy

NCT00957918
View directory record Official record
Conditions
Parkinson's Disease
Interventions
nicotine, placebo comparator
Drug · Other
Lead sponsor
Neuraltus Pharmaceuticals, Inc.
Industry
Eligibility
30 Years to 83 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
12
States / cities
Phoenix, Arizona • Los Angelis, California • Oxnard, California + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2011 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Expiratory Muscle Training for Persons With Neurodegenerative Disease

NCT00856518
View directory record Official record
Conditions
Parkinson's Disease, Multiple Sclerosis
Interventions
EMST, Sham
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
35 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Phase 2 Interventional

Methylphenidate and Parkinson's Disease

NCT00359723
View directory record Official record
Conditions
Parkinson's Disease
Interventions
methylphenidate
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 23, 2026, 1:42 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Diagnostic and Prognostic Biomarkers in Parkinson Disease

NCT00653783
View directory record Official record
Conditions
Parkinson Disease, Multiple System Atrophy, Progressive Supranuclear Palsy
Interventions
Not listed
Lead sponsor
The Parkinson Study Group
Network
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 31, 2008 · Synced Oct 23, 2026, 1:42 PM EDT
Completed No phase listed Observational

Parkinson's Research: The Organized Genetics Initiative

NCT00086073
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
1,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2011
U.S. locations
52
States / cities
Phoenix, Arizona • Fountain Valley, California • Irvine, California + 43 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2011 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Not applicable Interventional

Rehabilitation of Everyday Memory Impairment in Parkinson Disease: A Pilot Study

NCT01469741
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Prospective Memory Strategy
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

NCT00004451
View directory record Official record
Conditions
Parkinson Disease
Interventions
Glucose
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1998
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 1, 2005 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Not applicable Interventional

Stochastic Resonance Stimulation Effect on Gait Stability in Parkinson Disease

NCT06829342
View directory record Official record
Conditions
Parkinson Disease
Interventions
Stochastic Resonance (SR)
Device
Lead sponsor
University of Delaware
Other
Eligibility
40 Years to 85 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Phase 2 Interventional

Investigating the Cholinergic Contribution to Gait Dysfunction in Parkinson's Disease

NCT06903910
View directory record Official record
Conditions
Parkinson Disease
Interventions
Donepezil (Aricept)
Drug
Lead sponsor
University of Virginia
Other
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 23, 2026, 1:42 PM EDT
Terminated No phase listed Observational

Imaging a Cholinergic Biomarker of Cognition in Parkinson's Disease

NCT05034263
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Stony Brook University
Other
Eligibility
50 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 23, 2026, 1:42 PM EDT
Recruiting Not applicable Interventional

Evaluation of Neurocognitive Changes in Parkinson's Disease After Low Frequency Burst Stimulation

NCT05307055
View directory record Official record
Conditions
Parkinson Disease
Interventions
STN DBS - Theta Burst, STN DBS - Gamma
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 23, 2026, 1:42 PM EDT
Terminated Not applicable Interventional

Efficacy of a Recreation Therapy Wellness Recovery Program for Individuals With Parkinson's Disease

NCT04164043
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Wellness Recovery Program
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
45 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Not applicable Interventional

Treatment Protocol for PD Fatigue Management With CBT

NCT03747848
View directory record Official record
Conditions
Parkinson Disease
Interventions
CBT group
Behavioral
Lead sponsor
New York Institute of Technology
Other
Eligibility
21 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Oct 23, 2026, 1:42 PM EDT
Not yet recruiting Not applicable Interventional

Validation of cueStim for Reduction of Freezing of Gait in Parkinson's Disease

NCT07675408
View directory record Official record
Conditions
Parkinson's Disease With Freezing of Gait
Interventions
CueStim
Device
Lead sponsor
Fortis Medical Devices Limited
Industry
Eligibility
60 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
6
States / cities
Boca Raton, Florida • Daytona Beach, Florida • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Not applicable Interventional Results available

Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease

NCT00492115
View directory record Official record
Conditions
Parkinson's Disease, Sleep Disordered Breathing
Interventions
Continuous positive airway pressure (CPAP), Placebo CPAP
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Not applicable Interventional

Effects of Yoga on Parkinson's Disease

NCT02509611
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Hatha yoga
Other
Lead sponsor
University of Minnesota
Other
Eligibility
45 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Oct 23, 2026, 1:42 PM EDT
Not listed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Constipation in Parkinson's Disease

NCT02344485
View directory record Official record
Conditions
Parkinson's Disease, Constipation
Interventions
OMM treatment
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
40 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 23, 2026, 1:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fox BioNet Project: LRRK2-002

NCT03545425
View directory record Official record
Conditions
Parkinson Disease
Interventions
Biofluid samplings
Procedure
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
30 Years and older
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
5
States / cities
Boca Raton, Florida • Chicago, Illinois • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Oct 23, 2026, 1:42 PM EDT
Recruiting Not applicable Interventional

Sleep-specific DBS Therapy in Parkinson's Disease

NCT05962489
View directory record Official record
Conditions
Deep Brain Stimulation, Parkinson's Disease and Parkinsonism, Dystonia
Interventions
Clinically optimized deep brain stimulation
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 23, 2026, 1:42 PM EDT
Completed Phase 2 Interventional Results available

A Study to Explore the Safety And Tolerability of Doses of E2007 Up to a Maximum of 8 mg In Patients With Parkinson's Disease Who Experience End-of-Dose Wearing Off Motor Fluctuations

NCT00165789
View directory record Official record
Conditions
Parkinson's Disease
Interventions
E2007
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
10
States / cities
Little Rock, Arkansas • Oxnard, California • New Haven, Connecticut + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 23, 2026, 1:42 PM EDT
Active, not recruiting Not applicable Interventional

Partnered Dance Aerobic Exercise as a Neuroprotective, Motor and Cognitive Intervention in Parkinson's Disease

NCT04122690
View directory record Official record
Conditions
Parkinson's Disease, Exercise Therapy, Cognition
Interventions
PDAE, WAE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 23, 2026, 1:42 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research

NCT02402426
View directory record Official record
Conditions
Healthy, Neurodegenerative Disease
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
200,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 23, 2026, 1:42 PM EDT