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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:34 PM EDT

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Showing 553–576 of 1,450 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Primary Parkinsonism Clear all
Completed Phase 3 Interventional Results available

A Phase 3 Study With P2B001 in Subjects With Early Parkinson's

NCT03329508
View directory record Official record
Conditions
Parkinson Disease, Early Parkinson's Disease
Interventions
P2B001 0.6/0.75 mg, Rasagiline 0.75 mg, Pramipexole 0.6 mg, Marketed Pramipexole ER
Drug
Lead sponsor
Pharma Two B Ltd.
Industry
Eligibility
35 Years to 80 Years
Enrollment
544 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
45
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Los Angeles, California + 39 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Oct 27, 2026, 1:34 PM EDT
Recruiting Not applicable Interventional

Step Up to PD: A Community-based Walking Program for People With Parkinson's Disease

NCT06859528
View directory record Official record
Conditions
Parkinson Disease, Parkinson Disease, Idiopathic
Interventions
Community Walking Program
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
30 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 27, 2026, 1:34 PM EDT
Recruiting Phase 1 Interventional

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

NCT06683365
View directory record Official record
Conditions
Multiple System Atrophy, Parkinsons Disease
Interventions
Sural Nerve Graft to the Substantia Nigra, Sham surgery
Procedure
Lead sponsor
Craig van Horne, MD, PhD
Other
Eligibility
40 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 27, 2026, 1:34 PM EDT
Completed No phase listed Observational

Parkinson's Genes and Environment Study

NCT00367900
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
50 Years and older
Enrollment
3,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2021 · Synced Oct 27, 2026, 1:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Haptoglobin and Iron in Parkinson's Disease

NCT02422992
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Bastyr University
Other
Eligibility
35 Years to 92 Years
Enrollment
342 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
3
States / cities
San Diego, California • Kenmore, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 29, 2016 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Not applicable Interventional

Yoga for Anxiety in Adults

NCT04240899
View directory record Official record
Conditions
Parkinson Disease, Anxiety
Interventions
Tele-yoga
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Oct 27, 2026, 1:34 PM EDT
Recruiting Phase 3 Interventional

A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's

NCT04664634
View directory record Official record
Conditions
Dysphagia, Parkinson Disease
Interventions
Aria Sensor
Device
Lead sponsor
Northwestern University
Other
Eligibility
22 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Phase 2 Interventional Results available

Clinical Trial for Parkinson's Disease Using Allogeneic HB-adMSCs (Early and Moderate PD)

NCT04995081
View directory record Official record
Conditions
Parkinson Disease
Interventions
Biological/Vaccine: Allogeneic HB-adMSCs, Placebo
Biological · Other
Lead sponsor
Hope Biosciences Research Foundation
Industry
Eligibility
45 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 27, 2026, 1:34 PM EDT
Not listed No phase listed Observational

Subthalamic Nucleus Deep Brain Stimulation in Speech Study

NCT05493670
View directory record Official record
Conditions
Parkinson Disease, Dysarthria
Interventions
Not listed
Lead sponsor
Jeremy Greenlee
Other
Eligibility
21 Years to 84 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Phase 3 Interventional Results available

Atomoxetine for Freezing of Gait in Parkinson's Disease

NCT03651856
View directory record Official record
Conditions
Parkinson's Disease, Freezing of Gait
Interventions
ATM FOG in PD
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 27, 2026, 1:34 PM EDT
Completed No phase listed Observational

Diagnosis of PD and PD Progression Using DWI

NCT02837172
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Diffusion Weighted Imaging (DWI)
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Phase 1 Interventional

AAV2-GDNF for Advanced Parkinson s Disease

NCT01621581
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Convection enhanced delivery/AAV2-GDNF
Genetic
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 27, 2026, 1:34 PM EDT
Completed No phase listed Observational

High Order Spectral Analysis of Local Field Potential Data on a Subgroup of Parkinson's Disease Patients Who Are Carriers of Mutations in the Glucocerebrosidase (GBA) Gene Undergoing DBS Electrode Placement

NCT04268030
View directory record Official record
Conditions
Parkinson Disease
Interventions
collection of LFPs
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
30 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 9, 2021 · Synced Oct 27, 2026, 1:34 PM EDT
Completed No phase listed Observational

Capturing Parkinson's Disease Medication Side Effects During Daily Activities

NCT01429207
View directory record Official record
Conditions
Parkinson's Disease, Dyskinesia
Interventions
Not listed
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2012 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Not applicable Interventional

Self-Managed Intervention for Anxiety in Parkinson's Disease

NCT03859180
View directory record Official record
Conditions
Parkinson Disease, Anxiety
Interventions
Focused breathing
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 27, 2026, 1:34 PM EDT
Enrolling by invitation No phase listed Observational

AB-1005 Long-Term Follow-up Study

NCT07081841
View directory record Official record
Conditions
Parkinson's Disease, Multiple System Atrophy, Parkinson Variant
Interventions
Observation
Other
Lead sponsor
AskBio Inc
Industry
Eligibility
Not listed
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2038
U.S. locations
2
States / cities
San Francisco, California • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Not applicable Interventional Results available

Aerobic Exercise in Parkinson's Disease

NCT03808675
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Aerobic walking, Usual care with PD specific health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Phase 4 Interventional Results available

Trial to Evaluate The Efficacy Of Rotigotine on Parkinson's Disease-Associated Motor Symptoms And Apathy

NCT01782222
View directory record Official record
Conditions
Idiopathic Parkinson's Disease
Interventions
Rotigotine, Placebo
Drug · Other
Lead sponsor
UCB BIOSCIENCES GmbH
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
25
States / cities
Birmingham, Alabama • Oxnard, California • Ormond Beach, Florida + 21 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Not applicable Interventional

The Impact of Standard Medical Care (Dopamine) and Practice on Postural Motor Learning in Parkinson's Disease

NCT02593812
View directory record Official record
Conditions
Parkinson Disease
Interventions
Stepping training
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
50 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Phase 3 Interventional

Study of KW-6002 (Istradefylline) in Parkinson's Disease in Patients With Motor Response Complications on Levodopa

NCT00203957
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Istradefylline
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 11, 2013 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Phase 2 Interventional

JP-1730 to Treat Parkinson's Disease

NCT00040209
View directory record Official record
Conditions
Parkinson Disease
Interventions
JP 1730, IV Levodopa, IV Apomorphine
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 27, 2026, 1:34 PM EDT
Completed No phase listed Observational

Diagnosis and Natural History Study of Patients With Neurological Conditions

NCT00001549
View directory record Official record
Conditions
Alzheimer's Disease, Dementia, Movement Disorder, Multiple System Atrophy, Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Not applicable Interventional Results available

Light Therapy for PD - Dose Selection

NCT04291014
View directory record Official record
Conditions
Parkinson Disease, Sleep Disorder, Fatigue
Interventions
SunRay Light Boxes
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Phoenix, Arizona • Irvine, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 27, 2026, 1:34 PM EDT
Completed Not applicable Interventional Results available

Cortical Stimulation to Treat Mood and Behavioral Symptoms in Parkinson's Disease Patients

NCT03131817
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Medtronic Activa PC+S System with Chronic Neural Recording, Effort-Reward Decision-Making Task, Prefrontal Cortex Stimulation, Tablet-Based Mood Tracking (Immediate Mood Scaler)
Device · Behavioral · Other
Lead sponsor
Simon J. Little, MBBS, PhD
Other
Eligibility
30 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 27, 2026, 1:34 PM EDT