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ClinicalTrials.gov public records Last synced Oct 30, 2026, 2:53 AM EDT

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Showing 697–720 of 1,450 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Primary Parkinsonism Clear all
Active, not recruiting Phase 1 Interventional

Cont. of a Study to Evaluate Implanting Peripheral Nerve Grafts Into Subjects With Parkinson's Disease (PD) During DBS

NCT02369003
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Autologous Peripheral Nerve Graft
Procedure
Lead sponsor
Craig van Horne, MD, PhD
Other
Eligibility
40 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Whole Body Periodic Acceleration on Activity and Sleep In Parkinson's Disease

NCT02874261
View directory record Official record
Conditions
Sleep Disorders, Physical Activity
Interventions
Whole Body Periodic Acceleration
Device
Lead sponsor
New York Institute of Technology
Other
Eligibility
50 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Oct 30, 2026, 2:53 AM EDT
Recruiting Phase 2 Interventional

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

NCT07610369
View directory record Official record
Conditions
Depression, Parkinson's Disease (PD)
Interventions
Psilocybin (drug)
Drug
Lead sponsor
Yale University
Other
Eligibility
40 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 30, 2026, 2:53 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Galantamine Executive Function in Parkinson's Disease

NCT00211588
View directory record Official record
Conditions
Parkinson's Disease
Interventions
galantamine
Drug
Lead sponsor
Memorial Hospital of Rhode Island
Other
Eligibility
60 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 7, 2007 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Not applicable Interventional

Deep Brain Stimulation in Patients With Parkinson's Disease

NCT00586079
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep brain stimulation surgery.
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 82 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 18, 2016 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Not applicable Interventional

A Responsive Closed-Loop Approach to Treat Freezing of Gait in Parkinson's Disease

NCT02318927
View directory record Official record
Conditions
Parkinsons Disease
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 30, 2026, 2:53 AM EDT
Recruiting No phase listed Observational

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease

NCT07227896
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
AbbVie
Industry
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Georgetown, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 30, 2026, 2:53 AM EDT
Terminated Not applicable Interventional Results available

SHARPEN - Parkinson's Disease Dementia

NCT05987540
View directory record Official record
Conditions
Parkinson Disease Dementia
Interventions
Non-invasive brainstem stimulation
Device
Lead sponsor
Scion NeuroStim
Industry
Eligibility
50 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Boca Raton, Florida • Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 9, 2025 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Not applicable Interventional

Combining Aerobic Exercise and Virtual Reality for Cognitive-motor Rehabilitation in PD

NCT05385497
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Aerobic Exercise, Virtual Reality
Other · Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 30, 2026, 2:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

7T MRS in Parkinson's Disease

NCT01237210
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
45 Years to 75 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 30, 2026, 2:53 AM EDT
Completed No phase listed Observational

Observational Study Evaluating Long-Term Effectiveness of Duodopa/Duopa in Patients With Advanced Parkinson's Disease

NCT02611713
View directory record Official record
Conditions
Advanced Parkinson's Disease
Interventions
Not listed
Lead sponsor
AbbVie
Industry
Eligibility
18 Years to 99 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
19
States / cities
Birmingham, Alabama • Boca Raton, Florida • Gainesville, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 30, 2026, 2:53 AM EDT
Enrolling by invitation Not applicable Interventional

Movement State-dependent Adaptive DBS for PD

NCT07424508
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
Summit RC+S
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
21 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 30, 2026, 2:53 AM EDT
Enrolling by invitation Phase 4 Interventional

Quality Improvement and Practice Based Research in Neurology Using the EMR

NCT02670161
View directory record Official record
Conditions
Brain Tumors, Epilepsy, Migraine, Mild Cognitive Impairment, Concussion, Multiple Sclerosis, Neuropathy, Parkinson's, Restless Legs Syndrome, Stroke
Interventions
Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description)
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 100 Years
Enrollment
3,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 30, 2026, 2:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Postural Instability in Progressive Supranuclear Palsy

NCT01563276
View directory record Official record
Conditions
Progressive Supranuclear Palsy, Parkinson's Disease
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 30, 2026, 2:53 AM EDT
Suspended No phase listed Observational Accepts healthy volunteers

Perspectives on Healthcare Access and Equity of People With Parkinson's Disease Identifying as LGBTQ+

NCT05502055
View directory record Official record
Conditions
Parkinson Disease, Sexual Orientation
Interventions
Individual interviews, Focus Groups, National Survey
Other
Lead sponsor
Creighton University
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 6, 2024 · Synced Oct 30, 2026, 2:53 AM EDT
Not yet recruiting Not applicable Interventional

A System to Help With Freezing of Gait in Parkinson's Patients

NCT07542743
View directory record Official record
Conditions
Freezing of Gait Symptoms in Parkinson Disease
Interventions
ParkinSense System
Device
Lead sponsor
Barron Associates, Inc.
Industry
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 30, 2026, 2:53 AM EDT
Withdrawn Not applicable Interventional

Concurrent DBS Local Field Potential Analysis and Stimulation in a Closed-Loop Neuromodulation Device

NCT02731365
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Activa PC+S
Device
Lead sponsor
Vibhor Krishna
Other
Eligibility
22 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Oct 30, 2026, 2:53 AM EDT
Completed No phase listed Observational

Capturing Parkinson's Disease Medication Side Effects During Daily Activities

NCT01429207
View directory record Official record
Conditions
Parkinson's Disease, Dyskinesia
Interventions
Not listed
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2012 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Phase 3 Interventional

Study Evaluating Sumanirole for the Treatment of the Signs and Symptoms of Early Parkinson's Disease

NCT00058838
View directory record Official record
Conditions
Parkinson Disease
Interventions
sumanirole
Drug
Lead sponsor
Pfizer
Industry
Eligibility
30 Years and older
Enrollment
854 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
69
States / cities
Birmingham, Alabama • Huntsville, Alabama • Little Rock, Arkansas + 60 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2006 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Phase 3 Interventional Results available

Phase II Subthalamic Nucleus (STN) vs. Globus Pallidus (GPi) Trial

NCT01076452
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Bilateral Deep Brain Stimulation
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
22 Years and older
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
14
States / cities
Los Angeles, California • San Francisco, California • West Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2014 · Synced Oct 30, 2026, 2:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease

NCT06506058
View directory record Official record
Conditions
Parkinson Disease
Interventions
EVS and EEG
Device
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 30, 2026, 2:53 AM EDT
Terminated Not applicable Interventional Results available

Parkinson's Disease Inpatient Clinical Knowledge and Management

NCT03888287
View directory record Official record
Conditions
Parkinson Disease
Interventions
Watch Rx system, Parkinson's Disease Inpatient Clinical Knowledge and Management Program
Device · Other
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
22 Years and older
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Phase 2 Interventional Results available

Study of Magnetic Fields for Treatment of Parkinson's Disease

NCT00779155
View directory record Official record
Conditions
Parkinson's Disease
Interventions
The Resonator, The Resonator control
Device
Lead sponsor
pico-tesla Magnetic Therapies, LLC
Industry
Eligibility
30 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Littleton, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2011 · Synced Oct 30, 2026, 2:53 AM EDT
Completed Phase 1Phase 2 Interventional

A Study to Investigate a New Treatment in Patients With Parkinson's Disease

NCT03407378
View directory record Official record
Conditions
Parkinson Disease
Interventions
IPT803, Optional pharmacogenetic assessment, Questionnaires, Optional Blood-Oxygen-level Dependent functionalMRI, Motor Assessments before taking regular PD treatment, Motor Assessments on regular PD treatment
Drug · Genetic · Other
Lead sponsor
Tools4Patient
Other
Eligibility
35 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
5
States / cities
Aurora, Colorado • Gainesville, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Oct 30, 2026, 2:53 AM EDT