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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Primary Total Hip Arthroplasty Clear all
Terminated Phase 3 Interventional Results available

Trial of Prophylactic Tamsulosin for Postoperative Urinary Retention in Primary Total Hip and Knee Arthroplasty Patients

NCT02518971
View directory record Official record
Conditions
Postoperative Urinary Retention
Interventions
Tamsulosin, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
35 Years and older · Male only
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Jul 23, 2026, 2:19 PM EDT
Terminated No phase listed Observational

A Multi-centre, Prospective Surveillance to Assess Mid-term Performance of the Mpact Cup

NCT02196818
View directory record Official record
Conditions
Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head, Congenital Hip Dysplasia
Interventions
Mpact Acetabular Shell
Device
Lead sponsor
Medacta International SA
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
4
States / cities
Denver, Colorado • Boise, Idaho • Libertyville, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Phase 4 Interventional Results available

Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol

NCT04042233
View directory record Official record
Conditions
Prosthetic Joint Infection, Vancomycin, Joint Diseases
Interventions
Experimental Intraosseous vancomycin 500mg in 250 mL NS, Standard IV administration of vancomycin
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
19 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Phase 4 Interventional Results available

Intravenous Versus Oral Acetaminophen in Primary Total Hip Arthroplasty

NCT02839876
View directory record Official record
Conditions
Osteoarthritis, Acetaminophen, Arthroplasty, Hip Replacement
Interventions
Intravenous acetaminophen, Oral acetaminophen
Drug
Lead sponsor
Duke University
Other
Eligibility
56 Years to 85 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty

NCT03016078
View directory record Official record
Conditions
Arthroplasties, Hip Replacement, Arthroplasties, Knee Replacement
Interventions
Mepilex Border Post-Op Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Gilbert, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Phase 3 Interventional

Effect of Aprotinin on Transfusion Requirements and Blood Loss in Patients Undergoing Elective Primary Total Hip Replacement

NCT00668031
View directory record Official record
Conditions
Blood Loss, Surgical
Interventions
Trasylol (Aprotinin, BAYA0128), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
27
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 24 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2014 · Synced Jul 23, 2026, 2:19 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assess the Mid-term Performance of the Mpact Cup in Subjects Requiring Total Hip Arthroplasty

NCT03897595
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
MPact Cup
Device
Lead sponsor
Medacta USA
Industry
Eligibility
Not listed
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
5
States / cities
Parker, Colorado • Boise, Idaho • Libertyville, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

A Prospective Study to Evaluate the Effectiveness of a Haemostatic Agent in Primary Unilateral Total Hip Arthroplasty

NCT01285024
View directory record Official record
Conditions
Arthritis
Interventions
Vitagel
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional

HIP: Hip Imaging Protocol

NCT04126161
View directory record Official record
Conditions
Metabolic Profiling Muscle
Interventions
CT, Ultrasound
Procedure · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 23, 2026, 2:19 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparison of Anesthetic Techniques on Total Hip Arthroplasty

NCT01359865
View directory record Official record
Conditions
Osteoarthritis
Interventions
Lumbar Plexus Block
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2015 · Synced Jul 23, 2026, 2:19 PM EDT
Not listed No phase listed Observational

Survivorship and Patient Outcomes of Primary Total Hip Arthroplasty With the Ovation Hip System

NCT03986918
View directory record Official record
Conditions
Joint Diseases, Osteoarthritis, Hip, Rheumatoid Arthritis, Psoriatic Arthritis, Avascular Necrosis of Hip
Interventions
Routine Total Hip Arthroplasty
Device
Lead sponsor
Ortho Development Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Jul 23, 2026, 2:19 PM EDT
Active, not recruiting Phase 4 Interventional

A Prospective Randomized Controlled Trial of Dual-Mobility Components in Primary THA

NCT03371212
View directory record Official record
Conditions
Serum Metal Levels, Specifically Cobalt, Chromium, and Titanium
Interventions
Dual mobility cohort, Conventional cohort
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Phase 4 Interventional Results available

3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty

NCT03948386
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
isobaric bupivacaine, hyperbaric bupivacaine, isobaric mepivacaine
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 84 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Bensalem, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Prolonged Multimodal Analgesia for Post-Discharge Pain Control After Primary Total Hip Arthroplasty

NCT03358888
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
Multi-modal with as needed opioids, Multi-modal with one week of opioids offered, Standard of Care
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2019 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Physical Therapy Following Total Hip Arthroplasty

NCT04199390
View directory record Official record
Conditions
Hip Osteoarthritis, Surgery
Interventions
total hip arthroplasty
Procedure
Lead sponsor
Orthopedic One
Other
Eligibility
18 Years to 75 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional

RCT Determining Best Treatment for Geriatric Acetabular Fractures

NCT03419182
View directory record Official record
Conditions
Acetabular Fracture
Interventions
Open Reduction internal Fixation, Open Reduction Internal Fixation with Total Hip Arthroscopy
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 100 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Phase 3 Interventional Results available

Dabigatran Etexilate Compared With Enoxaparin in Prevention of Venous Thromboembolism (VTE) Following Total Hip Arthroplasty

NCT00657150
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
Enoxaparin, Dabigatran etexilate
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
2,055 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
10
States / cities
La Jolla, California • Aurora, Colorado • Englewood, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Jul 23, 2026, 2:19 PM EDT
Completed No phase listed Observational Results available

R3 Delta Ceramic Acetabular System PAS U.S.

NCT03056534
View directory record Official record
Conditions
Degenerative Joint Disease
Interventions
R3 Biolox Delta Ceramic Acetabular System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
189 participants
Timeline
2018 – 2023
U.S. locations
8
States / cities
Tampa, Florida • Tucker, Georgia • Annapolis, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2025 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty

NCT03409900
View directory record Official record
Conditions
Osteoarthritis, Total Hip Arthroplasty
Interventions
LPB, QLB
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 95 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Phase 1 Interventional

Tissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee Arthroplasty

NCT04294862
View directory record Official record
Conditions
Prosthetic Joint Infection
Interventions
TNP-2092
Drug
Lead sponsor
TenNor Therapeutics Limited
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Jul 23, 2026, 2:19 PM EDT
Terminated Not applicable Interventional Results available

An Open Label Trial to Decrease Signs and Symptoms of Orthostatic Hypotension Using Midodrine or Intravenous Fluid Bolus in Patients Following Total Hip Arthroplasty

NCT02154243
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
Midodrine, Intravenous fluid bolus
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 90 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Capsulectomy vs Capsulotomy With Repair in Direct Anterior Total Hip Arthroplasty

NCT02121964
View directory record Official record
Conditions
Hip Arthrosis, Osteoarthritis, Arthritis
Interventions
Capsulectomy in Direct Anterior Total Hip Arthroplasty, Capsulotomy in Direct Anterior Total Hip Arthroplasty
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 30, 2020 · Synced Jul 23, 2026, 2:19 PM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Effect of GRF6021 on Postoperative Recovery Following Primary Hip or Knee Arthroplasty

NCT03981419
View directory record Official record
Conditions
Postoperative Recovery
Interventions
GRF6021, Placebo
Biological · Other
Lead sponsor
Alkahest, Inc.
Industry
Eligibility
50 Years to 85 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Jul 23, 2026, 2:19 PM EDT
Enrolling by invitation Phase 4 Interventional

Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty

NCT07153003
View directory record Official record
Conditions
Post Operative Pain
Interventions
Oxycodone, Tramadol and Oxycodone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 23, 2026, 2:19 PM EDT