- Conditions
- Joint Contractures, Total Knee Anthroplasty, Knee Arthrofibrosis
- Interventions
- Hydraulic high Intensity Stretch Device, Standard Physical Therapy
- Device · Other
- Lead sponsor
- Ermi LLC
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Houston, Texas
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Showing 1–24
of 104
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2025
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Acute Pain, Regional Anesthesia Morbidity
- Interventions
- ropivacaine, bupivacaine, Sham Adductor Canal Catheter, Adductor Canal Catheter
- Drug · Device
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 40 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Sleep Quality Post-TKA, Postoperative Knee Function, Quality of Life After Primary TKA
- Interventions
- Doxepin 6 mg, Ramelteon 8 mg, Placebo Tablets
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 129 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Infection of Total Hip Joint Prosthesis
- Interventions
- Prevena Incision Management System
- Device
- Lead sponsor
- ProMedica Health System
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Toledo, Ohio
- Conditions
- Total Knee Replacement, Post-operative Nausea and Vomiting, Opioid Use, Anxiety, Depression, Post Operative Pain
- Interventions
- Elequil Lavender-peppermint Aromatabs, Elequil Almond-Oil Aromatabs
- Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Knee
- Interventions
- any knee joint arthroplasty device
- Device
- Lead sponsor
- Heekin Orthopedic Research Institute
- Other
- Eligibility
- 21 Years to 93 Years
- Enrollment
- 7,793 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2018
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Total Knee Replacement, Genicular Nerve Block, Opioid Use
- Interventions
- Bupivacaine Injection, Dexamethasone injection, Fentanyl, Mepivacaine
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 244 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Primary Total Hip Arthroplasty, Primary Total Knee Arthroplasty
- Interventions
- Diphenhydramine (Benadryl), Melatonin, Sleep Hygiene Education
- Drug · Dietary Supplement · Behavioral
- Lead sponsor
- James A. Keeney
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Osteo Arthritis Knee
- Interventions
- Isotonic saline, Ketamine Injectable Solution
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- Not listed
- Enrollment
- 75 participants
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Arthropathy of Knee
- Interventions
- OCSI Rehabilitator brace
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Blood Loss
- Interventions
- Tranexamic Acid, Aquamantys System, Control
- Drug · Device · Other
- Lead sponsor
- Eastern Maine Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 127 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Bangor, Maine
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Other Inflammatory Arthritis, Post-Traumatic Arthritis, Juvenile Rheumatoid Arthritis, Avascular Necrosis
- Interventions
- Total Knee Arthroplasty, Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 149 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2007
- U.S. locations
- 3
- States / cities
- Greensboro, North Carolina • Austin, Texas • Lakewood, Washington
- Conditions
- Osteo Arthritis Knee
- Interventions
- Melatonin 5 mg, Placebo
- Drug · Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 294 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Primary Total Knee Arthroplasty
- Interventions
- Pregabalin 50mg, Pregabalin 100mg, Pregabalin 150mg, Placebo
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty
- Interventions
- IO Administration of Cefazolin, IO Administration of Vancomycin, IV Administration of Cefazolin, IV Administration of Vancomycin
- Drug
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2035
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Arthroplasty, Replacement, Knee, Thromboembolism
- Interventions
- Dabigatran Dose 1 - day 2 to completion, Dabigatran Dose 1 - day 1, Dabigatran Dose 2 - day 2 to completion, Dabigatran Dose 2 - day 1, Enoxaparin
- Drug
- Lead sponsor
- Boehringer Ingelheim
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2,615 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2004
- U.S. locations
- 59
- States / cities
- Birmingham, Alabama • Northport, Alabama • Tucson, Arizona + 48 more
- Conditions
- Knee Osteoarthritis, Pain Management
- Interventions
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 167 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 6
- States / cities
- Little Rock, Arkansas • Pasadena, California • Dayton, Ohio + 3 more
- Conditions
- Osteo Arthritis Knee, Knee Arthritis, Monitoring Orthopedic Devices, Total Knee Arthroplasty, Total Knee Replacement
- Interventions
- Persona IQ
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 4
- States / cities
- Granger, Indiana • St Louis, Missouri • Charlotte, North Carolina + 1 more
- Conditions
- Knee Osteoarthritis, Blood Loss, Pain, Postoperative
- Interventions
- Tranexamic Acid Pill, Placebo
- Drug
- Lead sponsor
- Campbell Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Germantown, Tennessee
- Conditions
- Pain, Postoperative, Osteo Arthritis Knee
- Interventions
- Exparel
- Drug
- Lead sponsor
- Campbell Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Germantown, Tennessee
- Conditions
- Knee Disease, Arthritis Knee, Pain, Acute
- Interventions
- Morphine
- Drug
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain, Knee Extension
- Interventions
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Drug · Procedure
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Osteoarthritis, Post-traumatic Arthritis
- Interventions
- ATTUNE TKA with ATTUNE RUI, ATTUNE TKA with ATTUNE SUI
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 2
- States / cities
- La Jolla, California • Wilkes-Barre, Pennsylvania