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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:58 AM EDT

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Showing 145–168 of 291 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Problem Drinking Clear all
Completed Not applicable Interventional

Motivational Incentives for Alcohol Abstinence in American Indian and Native Alaskan Adults

NCT02174315
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Contingency Management
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Pullman, Washington
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Community-Based Strategy for Preventing Underage Drinking

NCT02448134
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Youth Access
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 19 Years
Enrollment
7,379 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional

An Internet-based Intervention for Problem Drinking

NCT00367575
View directory record Official record
Conditions
Alcoholism
Interventions
Internet personalized alcohol feedback (PAF)
Procedure
Lead sponsor
Centre for Addiction and Mental Health
Other
Eligibility
18 Years and older
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2010 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional

Alcohol, Suicide and HIV Prevention for Teens in Mental Health Treatment

NCT02228044
View directory record Official record
Conditions
Suicide, Alcohol Abuse, Drug Abuse, HIV
Interventions
Prevention program
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
13 Years to 18 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional

A Medical Assistant-Based Program to Promote Healthy Behaviors in Primary Care

NCT00273806
View directory record Official record
Conditions
Smoking, Problem Drinking, Sedentary Lifestyle, Unhealthy Diet
Interventions
Intervention for 4 behavioral risks by medical assistants.
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
6
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2008 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)

NCT02966873
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD), Addiction, Alcohol Abuse
Interventions
N-Acetylcysteine (NAC) Treatment, Cognitive Behavioral Therapy (CBT), Inactive Placebo Oral Capsule, Functional magnetic resonance imaging (fMRI), Proton magnetic resonance spectroscopy (MRS) Imaging
Drug · Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Phase 4 Interventional Results available

Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism

NCT00246441
View directory record Official record
Conditions
Social Anxiety Disorder, Social Phobia, Alcohol Use Disorder, Alcohol Abuse, Alcohol Dependence
Interventions
Paroxetine, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 21, 2026, 2:58 AM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)

NCT07216872
View directory record Official record
Conditions
Alcohol Use Disorder, Alcoholism, Alcohol Abuse, Alcohol Dependence, Alcohol Abuse/Dependence, Alcohol Addiction
Interventions
Deep TMS (DTMS), Sham (No Treatment)
Device
Lead sponsor
Brainsway
Industry
Eligibility
18 Years to 86 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
8
States / cities
Tuscaloosa, Alabama • La Jolla, California • West Palm Beach, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional

PFI for Pain-Related Anxiety Among Hazardous Drinkers With Chronic Pain

NCT05036499
View directory record Official record
Conditions
Alcohol Problem, Chronic Pain, Alcohol Abuse
Interventions
Personalized Feedback Intervention
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
21 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Oct 21, 2026, 2:58 AM EDT
Withdrawn Not applicable Interventional

The Therapeutic Workplace Intervention in Community Settings

NCT01841892
View directory record Official record
Conditions
Drug Abuse, Alcohol Abuse
Interventions
Community Therapeutic Workplace
Behavioral
Lead sponsor
University of Maryland, Baltimore County
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 5, 2017 · Synced Oct 21, 2026, 2:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Isolated During COVID-19: Effects of COVID-19's Social Restrictions on Loneliness and Psychosocial Symptomatology

NCT04440098
View directory record Official record
Conditions
Loneliness, Depression, Anxiety, Alcohol Abuse, Drug Abuse
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 35 Years
Enrollment
1,008 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 19, 2020 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional

Development and Testing of Adolescent Twelve-Step Facilitation

NCT01449981
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Drug Abuse, Drug Dependence
Interventions
Integrated Twelve-Step Facilitation, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 21 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 13, 2016 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Phase 2 Interventional Results available

Duloxetine Versus Pregabalin for Alcohol Dependence

NCT00929344
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Pregabalin, Duloxetine, Standardized behavioral therapy, Placebo
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 21, 2026, 2:58 AM EDT
Not listed Phase 1 Interventional

CHERL, Connecting Primary Care Patients With Community Resources to Facilitate Behavior Change

NCT00269009
View directory record Official record
Conditions
Tobacco Use Disorder, Alcohol Abuse, Lack of Physical Activity, Poor Diet
Interventions
CHERL
Behavioral
Lead sponsor
Great Lakes Research Into Practice Network
Network
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
3
States / cities
Flint, Michigan • Grand Rapids, Michigan • Marquette, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 11, 2007 · Synced Oct 21, 2026, 2:58 AM EDT
Recruiting Phase 2 Interventional

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

NCT06405607
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
Interventions
Psilocybin, Ketamine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional

Multimedia Toolkits to Implement 12-Step Recovery Concepts in Group Counseling

NCT02333357
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Multimedia 12-Step Toolkit, Treatment as Usual
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
18 Years and older
Enrollment
3,483 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
11
States / cities
Camden, New Jersey • Brooklyn, New York • Eagleville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 21, 2026, 2:58 AM EDT
Recruiting Phase 2 Interventional

The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking

NCT04084860
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
CI-581a, CI-581b, MBRP, MET
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personalized Drinking Feedback Interventions

NCT01211353
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Personalized Drinking Feedback, Education-Only
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 80 Years
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Oct 21, 2026, 2:58 AM EDT
Not listed Not applicable Interventional

Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking

NCT01881841
View directory record Official record
Conditions
Alcohol Abuse, Tobacco Use Disorder, Substance Use
Interventions
cMET
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 20 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Substance Use Risk Education (SURE) Project

NCT00289965
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Drinking
Interventions
Counselor-administered Brief Motivational Intervention (BMI), Alcohol 101 Plus (interactive CD-ROM), AlcoholEdu (Internet-based tutorial)
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years to 25 Years
Enrollment
703 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jul 26, 2011 · Synced Oct 21, 2026, 2:58 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Weaving Healthy Families Program

NCT03924167
View directory record Official record
Conditions
Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse, Diet Modification, Health Behavior, Health Knowledge, Attitudes, Practice, Relationship, Family, Relation, Parent-Child, Emotional Stress
Interventions
Weaving Healthy Families Program
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
5 Years to 120 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional

Mentored Clinical Career Award in Adolescent Substance Abuse

NCT00622219
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Randomized Drug Testing Trial
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Phase 3 Interventional

Medication and Counseling for Controlled Drinking (Project SMART)

NCT00444418
View directory record Official record
Conditions
Alcohol-related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy
Drug · Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 65 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2013 · Synced Oct 21, 2026, 2:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Screening and Management of Unhealthy Alcohol Use in Primary Care

NCT04248023
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
Interventions
Practice Facilitation
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
13,680 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 21, 2026, 2:58 AM EDT