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ClinicalTrials.gov public records Last synced May 22, 2026, 4:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Problem Solving Therapy Clear all
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder Not Otherwise Specified (NOS)
Interventions
Aripiprazole, Bupropion, Problem Solving Therapy
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Stroke, Quality of Life, Depression
Interventions
Problem-Solving Therapy, Stroke-Related Health Education
Behavioral · Other
Lead sponsor
Allina Health System
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced May 22, 2026, 4:09 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Behavior, Stress, Anxiety
Interventions
MindBoba, Mindshift CBT
Behavioral
Lead sponsor
IRIS Media Inc
Other
Eligibility
18 Years and older
Enrollment
268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced May 22, 2026, 4:09 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Depression, Epilepsy
Interventions
Program to Encourage Active, Rewarding Lives (PEARL)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 3, 2008 · Synced May 22, 2026, 4:09 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Traumatic Brain Injury, Executive Dysfunction, Emotional Dysregulation
Interventions
Online Emotional Regulation Treatment
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2015 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Smoking
Interventions
Telephone Counseling, Telephone Assessments
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Depression
Interventions
Problem Solving Therapy as Usual, Assisted Problem Solving Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Prostate Cancer
Interventions
Problem-Solving Therapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2005
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Diabetes Type 2
Interventions
Lifestyle and Activities Education Program (LEAP-AHEAD), Computer Automated Self-Management (CASM), Computer Automated Self-Management and Problem Solving Therapy (CAPS)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 75 Years
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2012 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Depression
Interventions
Tele-Problem-Solving Therapy, In-Person PST, Attention control
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
50 Years and older
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2015 · Synced May 22, 2026, 4:09 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Problem Solving Therapy plus Moving Forward, Problem Solving Therapy
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 64 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
No. Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 27, 2016 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Adherence
Interventions
Positive STEPS
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
16 Years to 29 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Depression
Interventions
Problem-solving therapy (PST), Case management (CM)
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years to 95 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
2
States / cities
San Francisco, California • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
PST-APPLE Watch group, Education-only control group
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 25 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
problem solving therapy, Sertraline
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced May 22, 2026, 4:09 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Problem Solving Therapy (PST) plus EUC
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced May 22, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), PTSD
Interventions
CBT + expressive writing, Wait-List Control
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Health Behavior
Interventions
Problem-solving intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2012 · Synced May 22, 2026, 4:09 AM EDT
Completed Phase 4 Interventional
View directory record Official record
Conditions
Depression
Interventions
Problem-Solving Treatment for Primary Care
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 9, 2013 · Synced May 22, 2026, 4:09 AM EDT
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
HIV/AIDS, Nicotine Dependence
Interventions
Varenicline, Nicotine patch, Standard treatment, Standard treatment + Managed Problem Solving (MAPS) adherence intervention
Drug · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced May 22, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Autism
Interventions
Pathways and Resources for Engagement and Participation (PREP)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
13 Years to 21 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced May 22, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Depression
Interventions
Problem Solving Treatment as usual (PST as usual), Problem Solving Treatment Aid (PST-Aid)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Cancer
Interventions
PS-OT, Usual care
Behavioral · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced May 22, 2026, 4:09 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
HIV Infections
Interventions
Focus Group, First Intervention Trial, Intervention Trial 2
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 24 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Los Angeles, California • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced May 22, 2026, 4:09 AM EDT