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ClinicalTrials.gov public records Last synced Oct 17, 2026, 1:01 AM EDT

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Showing 217–240 of 799 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Product Use Clear all
Completed Not applicable Interventional Results available

An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care

NCT04907045
View directory record Official record
Conditions
Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
Interventions
Health Coaching, Practice Facilitation, Standard Implementation
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,552 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 17, 2026, 1:01 AM EDT
Recruiting Not applicable Interventional

PASCAL Feasibility Study

NCT07301151
View directory record Official record
Conditions
Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
chatbot, no chatbot
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 17, 2026, 1:01 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Trial of Connecting to Promote Foster Teen Well-Being

NCT03157895
View directory record Official record
Conditions
Relationship, Family (Foster), Substance Use Prevention
Interventions
Connecting
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
11 Years to 15 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Cannabis Species Labeling and Marketing on Perceptual, Subjective and Objective Use Outcomes (Aim 2 Study)

NCT07513337
View directory record Official record
Conditions
Cannabis Use
Interventions
Strain label, Claim
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
21 Years and older
Enrollment
3,035 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Contingency Management for Drug Use: Does Age Matter?

NCT05521854
View directory record Official record
Conditions
Opioid Use Disorder, Methamphetamine Abuse, Cocaine Use Disorder
Interventions
DynamiCare app (app-based contingency management), Sham control
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Drug User Internet and Mobile Tech Use

NCT01871298
View directory record Official record
Conditions
Drug Abuse Illicit
Interventions
Pilot Website Evaluation Component
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2015 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Reward and Drug Effects on Mood and Brain Response

NCT04512365
View directory record Official record
Conditions
Cannabis Use, Healthy
Interventions
Placebo oral capsule, THC
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 25 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 17, 2026, 1:01 AM EDT
Not listed Phase 3 Interventional

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

NCT05000281
View directory record Official record
Conditions
Tibia Fracture
Interventions
Ibuprofen
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Oct 17, 2026, 1:01 AM EDT
Completed No phase listed Observational

Kentucky Access to Recovery Evaluation

NCT05889702
View directory record Official record
Conditions
Substance Use Disorders, Treatment Adherence and Compliance
Interventions
KATR Linkage Strategy
Behavioral
Lead sponsor
Terry Bunn
Other
Eligibility
18 Years and older
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Berea, Kentucky • Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 4 Interventional Results available

Increasing Naloxone Access for Persons Who Use Opioids

NCT04303000
View directory record Official record
Conditions
Naloxone
Interventions
Opioid Overdose Education with Naloxone Distribution, Opioid Overdose Education
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Anniston, Alabama • Gadsden, Alabama • Mobile, Alabama + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 3 Interventional

Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users

NCT00228007
View directory record Official record
Conditions
Depression, Substance-Related Disorders, HIV Infections
Interventions
Antidepressant Medication
Drug
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
265 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 22, 2013 · Synced Oct 17, 2026, 1:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI

NCT01036711
View directory record Official record
Conditions
Nicotine Dependence, Drug Abuse
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
249 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Interactions Between Intravenous Cocaine and Acetazolamide or Quinine

NCT01851473
View directory record Official record
Conditions
Cocaine Use, Pharmacokinetics
Interventions
cocaine, quinine, acetazolamide
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional Results available

Study to Assess the Potential for Adrenal Suppression Following Treatment With DSXS in Patients With Plaque Psoriasis

NCT02601469
View directory record Official record
Conditions
Plaque Psoriasis
Interventions
DSXS
Drug
Lead sponsor
Sun Pharmaceutical Industries, Inc.
Industry
Eligibility
2 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Hawthorne, New York
Source: ClinicalTrials.gov public record
Updated Dec 7, 2018 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 3 Interventional

A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)

NCT00000751
View directory record Official record
Conditions
HIV Infections, Pregnancy
Interventions
Anti-HIV Immune Serum Globulin (Human), Globulin, Immune, Zidovudine
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
13 Years to 60 Years · Female only
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
48
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2008 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Study of the Effects of Motivational Enhancement Therapy on Alcohol Use in Chronic Hepatitis C Patients

NCT00596960
View directory record Official record
Conditions
Alcohol Dependence, Chronic Hepatitis C
Interventions
Motivational Enhancement Therapy (MET), Health education
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Minneapolis, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 28, 2014 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Couples Health Project: Couples-based Intervention to Reduce Drug Use and HIV Transmission Risk

NCT03386110
View directory record Official record
Conditions
Risk Behavior, Drug Use, Sex, Anal
Interventions
Couples Health Project (CHP), Education
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional

The Peer-Based Retention of People Who Use Drugs in Rural Research

NCT03885024
View directory record Official record
Conditions
Drug Use, Peer Influence
Interventions
Retention Video
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Atlanta, Georgia • Lexington, Kentucky • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 3 Interventional

A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients

NCT00002382
View directory record Official record
Conditions
HIV Infections
Interventions
Saquinavir
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
13 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Nutley, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional Results available

Study of the Medication Prazosin for Alcohol Dependence

NCT00762710
View directory record Official record
Conditions
Alcoholism
Interventions
Prazosin medication, Placebo medication
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 4 Interventional

The Kentucky Viral Hepatitis Treatment Study

NCT03949764
View directory record Official record
Conditions
Hepatitis C, Opioid-Related Disorders, Injection Drug Use
Interventions
Sofosbuvir/velpatasvir (Epclusa®)
Drug
Lead sponsor
Jennifer Havens
Other
Eligibility
18 Years and older
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Hazard, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 17, 2026, 1:01 AM EDT
Active, not recruiting Not applicable Interventional

Leveraging Parents and Peers to Increase Recovery Capital in Emerging Adults

NCT06414993
View directory record Official record
Conditions
Polysubstance Drug Use (Indiscriminate Drug Use)
Interventions
Contingency Management for Emerging Adults (CM-EA), Standard Peer Recovery Support Services (PRSS) +Vocational/Educational (V/E) Skill Building services
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
8
States / cities
Hiram, Georgia • Bloomington, Illinois • Granite City, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Frontoparietal Synchronization to Modulate Drug Craving in Opioid Use Disorder

NCT03907644
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Transcranial Alternating Current Stimulation (tACS)
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 61 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional

TDCS to Reduce Craving in Cocaine Addiction- Phase 2 Study

NCT04994821
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
transcranial direct current stimulator (tDCS), Cognitive Reappraisal
Device · Behavioral
Lead sponsor
Soterix Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 17, 2026, 1:01 AM EDT