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ClinicalTrials.gov public records Last synced Sep 17, 2026, 2:08 PM EDT

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Showing 1–24 of 235 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Pelvic Organ Prolapse
Interventions
Mechanical Bowel Prep, No Mechanical Bowel Prep
Other
Lead sponsor
Boston Urogynecology Associates
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative, Colostomy, Ileostomy - Stoma, Rectal Prolapse, Intestinal Polyposis, Lymphoma, Endometriosis, Intestinal Volvulus
Interventions
Not listed
Lead sponsor
novoGI
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
3
States / cities
Atlamonte Springs, Florida • Port Charlotte, Florida • Springfield, Missouri
Active, not recruiting Not applicable Interventional

Perineal Massage for Pessary Examinations

NCT06416982
Conditions
Prolapse, Vaginal, Stress Urinary Incontinence, Pessaries, Pain
Interventions
Perineal massage
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Raleigh, North Carolina
Conditions
Same Day Discharge, Pelvic Organ Prolapse, Total Vaginal Hysterectomy
Interventions
Pelvic Reconstructive Surgery
Procedure
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Pelvic Organ Prolapse
Interventions
Platelet rich plasma (PRP) Injection, Placebo
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Vaginal Creams to Reduce Vaginal Erosion in Pessary Users

NCT02316249
Conditions
Atrophy of Vagina, Vaginal Ulceration, Vaginitis
Interventions
Estradiol, placebo
Drug · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Great Neck, New York
Completed Not applicable Interventional Results available

Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies

NCT01124916
Conditions
Pelvic Organ Prolapse
Interventions
Robotic assisted laparoscopic abdominal sacrocolpopexy, Standard laparoscopic abdominal sacrocolpopexy
Procedure
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Los Angeles, California • Maywood, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Voiding Trials After Midurethral Sling for Stress Incontinence

NCT02400034
Conditions
Stress Urinary Incontinence, Urethral Hypermobility, Cystocele
Interventions
Voiding trial
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Great Neck, New York
Conditions
Pelvic Organ Prolapse, Perioperative/Postoperative Complications
Interventions
Gabapentin, Gabapentin Placebo
Drug
Lead sponsor
Joseph Kowalski
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery

NCT03052816
Conditions
Pain, Postoperative, Pelvic Organ Prolapse
Interventions
Ice T, Motrin/Percocet/Dilaudid for breakthrough
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Completed No phase listed Observational Accepts healthy volunteers

A Novel Assay for Predicting Surgical Outcomes in Pelvic Organ Prolapse

NCT03534830
Conditions
Prolapse Genital
Interventions
MRI
Diagnostic Test
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Pelvic Organ Prolapse, Patient Preparedness
Interventions
Preoperative counseling office visit, Preoperative counseling phone call
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 99 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Phase 2 Interventional

Materna Prep Study Phase II

NCT06126328
Conditions
Vaginal Delivery, Pelvic Organ Prolapse
Interventions
Materna Prep Device
Device
Lead sponsor
Materna Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Mountain View, California + 11 more
Conditions
Pelvic Organ Prolapse, Patient Satisfaction
Interventions
new preoperative handout, old preoperative handout
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Stress Incontinence Female, Pelvic Organ Prolapse
Interventions
Midurethral sling placed before robotic sacrocolpopexy, Midurethral sling placed after robotic sacrocolpopexy
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Albany, New York
Conditions
Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Standardized visual presentation
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Pelvic Organ Prolapse
Interventions
Performing robotic supracervical hysterectomy
Procedure
Lead sponsor
Atlantic Health System
Other
Eligibility
Not listed
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Morristown, New Jersey
Conditions
Pelvic Organ Prolapse
Interventions
Device- Robotic sacral colpopexy
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Conditions
Vaginal Prolapse
Interventions
AMS Prolapse Product
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
1,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Whitinsville, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Development Study Using Vaginal Tactile Imager

NCT01111916
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years to 65 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
2
States / cities
Princeton, New Jersey • Allentown, Pennsylvania
Conditions
Postoperative Pain, Pelvic Organ Prolapse, Trigger Point Injection, Sacrospinous Ligament Fixation
Interventions
marcaine and kenalog
Drug
Lead sponsor
Kettering Health Network
Other
Eligibility
21 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Dayton, Ohio
Conditions
Pelvic Organ Prolapse
Interventions
liberal postoperative activity, Restricted postoperative activity
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
3
States / cities
Chicago, Illinois • Roanoke, Virginia
Conditions
Pelvic Floor Disorders
Interventions
Postmenopausal, topical vaginal estrogen cream, Placebo Comparator: Postmenopausal, topical placebo cream
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
21 Years to 70 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Uterine Prolapse
Interventions
Restorelle Smartmesh
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Dearborn, Michigan